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O equipamento de defesa mais barato do Brasil! Que loucura! INSCREVA-SE -- Instagram do canal: https://www.instagram.com/cout.samuel/?hl=pt-br -- SEJA MEMBRO - Sua ajuda é essencial para manter a criação de conteúdo https://www.youtube.com/channel/UCmvhlpPYY8qIyzNkS8fC0EQ/join
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In this conversation, Dr. Riley Kirk and Dr. Josh Kaplan delve into the complexities of cannabis research, particularly focusing on CBD and its therapeutic potential for conditions like epilepsy. Dr. Kaplan shares his journey into cannabis research, highlighting the significance of understanding CBD's mechanisms, the role of GPR55 in seizure management, and the challenges of dosing CBD effectively. They also discuss the entourage effect, the importance of personalized medicine, and the ongoing research into terpenes and their interactions with cannabinoids. The conversation emphasizes the need for further exploration in cannabis research to develop safe and effective therapies, especially for vulnerable populations like children. In this conversation, Josh Kaplan discusses the therapeutic potential of CBD, particularly in relation to traumatic brain injuries and neurodegenerative diseases. He emphasizes the safety of CBD compared to THC and explores its role in preventative treatments. The conversation also delves into ongoing clinical trials, particularly within the NFL, and the challenges faced in cannabis research, including dosing and the variability of individual responses to cannabinoids. Kaplan highlights the importance of understanding the entourage effect and the need for more personalized approaches in cannabis treatment. More about Dr. Kaplan: Dr. Kaplan is an Associate Professor in the Behavioral Neuroscience Program. His expertise is in neurophysiology, neuropharmacology, and animal behavior techniques, which his lab uses to study the therapeutic benefits and developmental consequences of cannabis in pre-clinical rodent models. His research seeks to optimize cannabinoid and terpene compositions to maximize benefit and minimize adverse consequences. Dr. Kaplan has a strong passion for teaching and communicating science. His scientific writing specializes in the science of cannabis and its medicinal utility. He was included in High Times' 100 Most Influential People in Cannabis (2018) and Cannabis Newsletter's Top 100 (2021). Follow Dr.Kaplan’s research: https://wp.wwu.edu/kaplanlab/ Preorder my book Reefer Wellness! https://www.amazon.com/Reefer-Wellness-Understanding-Cannabis-Medicine/dp/0593847156 Seed Giveaway Thank you to Royal Queen Seeds and Last Green Valley Seeds for donating to this week's giveaway! To enter, fill out the form below, winners will be selected at random. https://forms.gle/1vWtsBMGaux9x5Mf6 ✨ Want Exclusive Content? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. www.Patreon.com/Cannabichem 🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Timestamps: 00:00 Introduction to Cannabis Research and Its Importance 03:04 The Journey into CBD and Epilepsy 06:00 Understanding CBD's Mechanism of Action 08:54 The Role of GPR55 in Seizure Management 12:00 Exploring the Entourage Effect 14:53 Challenges in Dosing CBD for Multiple Conditions 18:02 Personalized Medicine and Endocannabinoid System 21:01 Researching Terpenes and Their Effects 24:01 Future Directions in Cannabis Research 34:12 The Therapeutic Potential of CBD 36:34 Traumatic Brain Injury and CBD Research 39:34 Clinical Trials and NFL Studies 48:01 Challenges in Cannabis Research 54:27 Dosing and Efficacy of CBD 01:00:24 The Entourage Effect and Individual Variability
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Hey guys, I'm back with another video! This time, we will cover the basics of cannabinoids. We'll discuss the history, biochemistry, pharmacology and total synthesis of these highly useful natural products. Recent research is used as an example of the importance and potential of cannabinoids in medicine. https://www.instagram.com/totalsynthesis_official/ https://www.patreon.com/totalsynthesis https://www.total-synthesis.com This video does not endorse the preparation of illegal substances. No detailed steps or procedures for syntheses of illegal drugs are discussed. I hope it's clear that here we focus on fascinating aspects of science and on the potential that compounds have in improving the lives of patients. 00:00 Introduction of medical cannabinoids; Applications of cannabidiol (CBD) and tetrahydrocannabinol (THC) for treatment of epilepsy and other conditions; Introduction of legal high of liverwort 04:35 History and Isolation of THC; Discovery of the endocannabinoid system, endocannabinoid receptors (CB1 and CB2) and endocannabinoids anandamide and arachidonylglyceride; CB1 antagonists as anti-obesity drugs; Total synthesis of THC and CBD by Raphael Mechoulam at the Weizmann Institute 15:18 Can you get legally high from moss or liverwort? Summary of pharmacological results from the key paper, based on work of Professor Gertsch and co-workers at the University of Bern; Tetrad test, Prostaglandins; Implications for medicinal applications 21:32 Organic synthesis and two total syntheses of cis-perrottetine by Professor Carreira at ETH Zürich (2018) and Professor Kim at Seoul University (2008); Discussion of key steps and synthetic strategies and reaction mechanisms 28:17 Closing remarks Mechoulam interview/documentary: - The Scientist (2015): https://www.youtube.com/watch?v=fu6FhJIyTEc Liverwort paper: - Uncovering the psychoactivity of a cannabinoid from liverworts associated with a legal high (Science Advances 2018, 4, 2166): http://advances.sciencemag.org/content/4/10/eaat2166 Some recommended books on organic synthesis: - Clayden, Greeves, Warren; Organic Chemistry (basic organic chemistry knowledge) - Wyatt, Warren; Organic Synthesis: The Disconnection Approach (excellent introduction to retrosynthesis) - Kurti, Czako; Strategic Applications of Named Reactions in Organic Synthesis (extensive toolkit of reactions and applications thereof with common conditions) - Nicolaou et al; Classics in Total Synthesis 1-3 (the ultimate total synthesis trilogy) - Nicolaou; Molecules That Changed the World (the world's most important molecules and their impact on everyday life) - Carreira, Kvaerno; Classics in Stereoselective Synthesis (compilation of the groundbreaking methods of stereoselective synthesis and application to synthesis of stereochemically complex structures)
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Have you been considering taking a tolerance break from smoking weed? Have you been thinking about quitting smoking weed or taking a T BREAK? Are you struggling with weed withdrawal or marijuana withdrawal symptoms during your tolerance break? Are you wondering how to take a tolerance break? If you said yes to any of these questions about cannabis this AddictionMindset recovery coaching video is for you! In this brief video Dr. Frank the founder of Addiction Mindset recovery coaching breaks down the basics of how to take a tolerance break once and for all! If you struggle with weed addiction or cannabis substance use disorder or cannabinoid hyperemesis syndrome this video is for you! Before you pick up the delta 8 or THC O or delta 10 get your free copy of the tolerance break survival guide with the links below: Free Tolerance Break Checklist/ Survival Guide (T BREAK TIME) https://stan.store/AddictionMindset Book a 1:1 Addiction Recovery Call with Dr. Frank: https://stan.store/AddictionMindset Join our AddictionMindset mental health community: https://stan.store/AddictionMindset High performance planner link: https://amzn.to/41wS1NC Best book on weed addiction: https://amzn.to/41sf6RG Best book on quitting smoking: How to quit smoking https://amzn.to/42I8IXw #tolerancebreak #addictionmindset #weedwithdrawal #quitsmoking
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Thanks for watching edtalks420plus,
here are some legal cannanbis clinics in the uk.
https://medbud.wiki/
Mine - https://cannabisaccessclinics.co.uk/pharmacy/cedarwood-pharmacy/
alternative - https://curaleafclinic.com/
Eds channel -
Watch my other video of how to get a legal uk cannabis prescription here if you need one !
Did you know your employer is unable to sack you for taking legal medicine? Under the equalities act !
Please do me a favour and click the like and subscribe button, I REALLY DO appreciate it. And share with anyone that will need and also on social media too.
Thanks a lot
Ed
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Taken from Jazz, 1978 and 'Greatest Video Hits 1' compilation of 2002. This is a different version to that which first appeared on 'Greatest Flix' in 1981. Click here to buy the DVD with this video at the Official Queen Store: http://www.queenonlinestore.com Subscribe to the official Queen channel Here https://Queen.lnk.to/Subscribe Watch more: https://Queen.lnk.to/OfficialMusicVideos About Queen: Welcome to the official Queen channel. Subscribe today for exclusive Queen videos, including live shows, interviews, music videos & much more. Connect with Queen Online: Visit the official Queen Website: https://Queen.lnk.to/Official Follow Queen on Instagram: https://Queen.lnk.to/Instagram Follow Queen on TikTok: https://Queen.lnk.to/TikTokOfficial Follow Queen on Twitter: https://Queen.lnk.to/Twitter #QueenTheGreatest #Queen #BicycleRace #Jazz #GreatestHits Queen - Bicycle Race (Official Video) https://www.youtube.com/user/queenofficial
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I bought some flavored seltzer containing full spectrum CBD extract at a local store to see how they compare to my preferred full spectrum cbd. Watch to see what I think!