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Delta 8 THC Compared to Delta 9 THC Professor DeBacco Delta-9 THC Explained As an activator of the CB1 receptor, delta-9-tetrahydrocannabinol — commonly known as THC is the main intoxicating component of cannabis. THC intoxication has been shown to increase blood flow to the prefrontal cortex, the region of the brain responsible for decision-making, attention, motor skills, and other executive functions. When THC binds to CB1 receptors in the brain's reward system, it can trigger feelings of euphoria. Much of THC's ability to relieve pain is due to its interaction with CB1 receptors in the midbrain. Delta-8 THC Explained Delta-8-THC is an isomer of Delta-9 THC It only differs from delta-9-THC by the placement of one atomic double bond. Generally, this chemical is produced in a lab, not extracted directly from the plant. It is actually synthesized from CBD Isolate. This creates a legal loophole, because the product is being sold as “hemp derived” even though it is actually a chemically produced THC isomer. Extraction Difference Delta 9 THC is a major cannabinoid that can be found in abundance and is easily extracted from in cannabis. Extracting Delta 8 THC is more challenging because it is a minor cannabinoid Synthesizing Delta 8 from CBD Delta 8 can be synthesized entirely from CBD with the use of solvents. Deriving Delta 8 from hemp ensures the final product is under the 0.3% THC level to be federally legal. Steps to Synthesize D8 THC from CBD isolate Dissolve into non-polar solvent of choice. Common solvents include heptane. Add a Lewis acid, like alumina, p-toluenesulfonic, or hydrochloric. Maintain the mixture at a temperature of 100 degrees C while continually stirring for upwards of 18 hours. Once the chemical reaction is complete, and the upper phase is separated, wash and neutralize the solution with 5% NaHCO3 Test for purity and contaminants using HPLC, separate the converted mixture into its “many cannabinoid parts”. Conversion is never 100% Different Effects Delta 9 is considerably more potent effects than Delta 8. Ex. paranoid delusions, mental fog, impaired motor skills, and increased feelings of anxiety. Delta 8 is reported to provide a more muted experience with most users feel a great sense of calm and clarity. However, many have reported a definite “high” to the experience, but not enough to impair the ability to form coherent thoughts or focus on activities. Onset Time Difference Delta 9 has an onset that is more rapid and instantaneous Delta 8 works slowly and gradually as it eases users into a more mellow state Similar End Products Both can be smoked as a flower, inhaled through vaping, consumed in edible form also with a wide variety of topicals, capsules, tinctures, edibles and other products. Legality Delta 9 THC in any amount over 0.3% is not legal at a federal level. State level depends entirely on their local laws. Delta 8 is still technically legal on a federal level. That's because of the ambiguities of the 2018 Farm Bill, which legalized hemp production. There is nothing within the bill that prohibits deriving Delta 8 from hemp and creating products with the compound. Hazy Area The psychoactive nature of Delta 8 has prompted a fair number of bans at the state level, though. Currently there are 15 states that restrict the sale and use of Delta 8 products, with another 6 states where legal action is pending. So while Delta 8 is more widespread at the moment than Delta 9, how long that will last has yet to be determined. Availability Delta 8 since it is federally legal can be shipped across state lines, unlike Delta 9. There are a lot more online retailers for Delta 8 products as a result. Remember: Delta 8 products are not regulated by the FDA, so it is up to you to seek out lab results tested from a third party lab. Delta 9 vs Delta 8 Delta 9 might be considered the “classic” choice by some within the cannabis community, Delta 8 has been quickly gaining in popularity due to its milder effects and legal availability. Since this is an isomer of Delta 9 it is also likely to come under some form of regulation in the future even though that may not currently be the case. Link to Lecture Slides: https://drive.google.com/file/d/1bTA2zy0R_dAN7zVTCzp0_XImiOmyHGlx/view?usp=sharing *Due to the description character limit the full work cited for "Delta 8 THC Compared to Delta 9 THC" can be viewed at... https://drive.google.com/file/d/1ET_IIIsXWyUZ_FuID5oXLumMOchlYSzr/view?usp=sharing
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Cannabidiol, more commonly known as CBD, has gained popularity in recent years for its potential health benefits. Many people use CBD products for various purposes, such as pain relief, anxiety management, and improved sleep. While CBD is generally considered safe, it is essential to be aware of potential toxicity symptoms that may occur with excessive use. In this article, we will discuss how to identify Cannabidiol toxicity symptoms and what you need to know to stay safe.
Understanding Cannabidiol Toxicity
Cannabidiol is a chemical compound found in cannabis plants, such as hemp and marijuana. Unlike its counterpart THC, CBD is not psychoactive, meaning it does not produce a “high” feeling. CBD interacts with the endocannabinoid system in the body, which plays a role in regulating various functions, such as mood, pain perception, and immune response.
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While CBD is generally well-tolerated by most people, consuming high doses can lead to adverse effects. Cannabidiol toxicity can manifest in various ways, such as nausea, fatigue, dry mouth, and changes in appetite. In severe cases, CBD overdose can cause liver toxicity and drug interactions with other medications.
To avoid experiencing Cannabidiol toxicity symptoms, it is crucial to follow recommended dosages and consult with a healthcare professional before using CBD products, especially if you are taking other medications or have underlying health conditions. By being informed and cautious, you can safely incorporate CBD into your wellness routine without risking adverse effects.
Common Symptoms of Cannabidiol Toxicity
Identifying Cannabidiol toxicity symptoms can help you take appropriate action if you experience any adverse effects from CBD use. Some common signs of Cannabidiol toxicity include digestive issues, such as diarrhea, vomiting, and stomach cramps. These symptoms may indicate that you have consumed too much CBD or that your body is sensitive to the compound.
In addition to digestive problems, Cannabidiol toxicity can also manifest as fatigue and drowsiness, which may affect your daily activities and productivity. If you find yourself feeling unusually tired or sluggish after taking CBD, it may be a sign that you need to adjust your dosage or frequency of use. It is essential to listen to your body’s signals and prioritize your well-being when using CBD products.
Another common symptom of Cannabidiol toxicity is dry mouth, also known as cottonmouth. This sensation occurs when CBD interferes with saliva production in the mouth, leading to a dry and sticky feeling. While dry mouth is generally mild and temporary, it can be bothersome for some individuals. To alleviate this symptom, staying hydrated and chewing sugar-free gum or candies can help stimulate saliva production and relieve dry mouth discomfort.
What to Do If You Experience Cannabidiol Toxicity
If you suspect that you are experiencing Cannabidiol toxicity symptoms, it is essential to stop using CBD products immediately and seek medical attention if necessary. While most cases of CBD overdose are mild and resolve on their own, severe symptoms such as difficulty breathing, rapid heart rate, or confusion require prompt medical intervention.
To manage Cannabidiol toxicity symptoms at home, you can try drinking plenty of water to stay hydrated, resting to allow your body to recover, and avoiding consuming any more CBD products until your symptoms subside. It is crucial to listen to your body and prioritize your health and safety when using CBD to prevent adverse effects and ensure a positive experience with cannabidiol.
Overall, being aware of Cannabidiol toxicity symptoms and knowing how to identify them can help you use CBD products safely and effectively. By understanding the potential risks associated with CBD use and taking necessary precautions, you can enjoy the benefits of Cannabidiol without experiencing harmful side effects. Remember to start with low doses, gradually increase as needed, and consult with a healthcare provider if you have any concerns or questions about using CBD products.
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