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INCRETIN HORMONES, DPP4 INHIBITORS, GLP-1AGONIST. Incretins are released by intestinal endocrine cells. They are GLP-1,GIP. they increase insulin secretion. They are released in response to oral or intravenous glucose, more to oral glucose.DPP4 INHIBITORS inhibit the degradation of incretins thus increase insulin secretion. GLP -1 agonists activates GLP-1 receptors in pancreatic beta cells thus increase insulin secretion thus lower blood glucose.

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Welcome to Episode 1 of The Take It Back Method — where we finally tell the truth about weight loss. In this episode, Joseph Debban FNP, certified by the Obesity Medicine Association and a national committee member, breaks down why most people fail to lose weight — and how to fix it for good. We’ll expose the two most common (and broken) approaches in medicine today: the “just use willpower” crowd and the “just take a shot and go home” crowd. Then, we’ll walk you through the real solution — the Take It Back approach to metabolic reset. In this episode, you’ll learn: Why insulin resistance, thyroid issues, PCOS, and hormone imbalances often go undiagnosed The simple structure behind the Debban Diet (and why it works when others don’t) How medications like Contrave, Qsymia, and GLP-1s fit into a real long-term plan Why muscle is medicine (and what’s coming in the next episode) The truth about set point theory — and why weight regain is not your fault This isn’t just another weight loss podcast. This is a revolution in how we reclaim health, energy, and vitality — one pillar at a time. Subscribe, share, and follow — and let’s Take It Back together. #weightloss #takeitbackmethod #obesitymedicine #metabolichealth #GLP1 #debbandiet #hormonetherapy #wellness #fatloss #healthspan

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