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Semaglutide is a type of medication that has garnered attention for its potential to aid in weight loss. Originally developed to treat type 2 diabetes, this drug has now been approved for use in helping individuals lose weight by decreasing appetite and calorie intake. Semaglutide pills work by mimicking the effects of a hormone called GLP-1, which helps regulate blood sugar levels and reduces food cravings. This article will provide a detailed review of how semaglutide pills aid in weight loss, exploring its mechanism of action, effectiveness, potential side effects, and more.
Mechanism of Action
Semaglutide works by binding to GLP-1 receptors in the brain, which helps regulate appetite and food intake. This hormone is normally released by the gut after eating, signaling to the brain that the body is full. By mimicking the effects of GLP-1, semaglutide can help reduce hunger and cravings, leading to decreased calorie intake and weight loss. In addition to its effects on appetite, semaglutide also slows down gastric emptying, which can further contribute to feelings of fullness and satiety.
The effectiveness of semaglutide in aiding weight loss has been demonstrated in several clinical trials. In one study, participants who took semaglutide lost significantly more weight compared to those who took a placebo. On average, individuals who took semaglutide lost around 15% of their body weight, which is considered to be a significant amount. These results have led to the approval of semaglutide for weight loss by regulatory authorities in several countries, providing a new option for individuals struggling to lose weight through diet and exercise alone.
Potential Side Effects
As with any medication, semaglutide may cause side effects in some individuals. Common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation. These side effects are typically mild and temporary, but they can be bothersome for some people. In some cases, semaglutide may also cause more serious side effects, such as pancreatitis or allergic reactions. It is important to talk to your healthcare provider before starting semaglutide to discuss the potential risks and benefits.
In addition to its potential side effects, it is also important to note that semaglutide is not suitable for everyone. This medication is not recommended for individuals with a history of pancreatitis, thyroid cancer, or certain other medical conditions. It is also not recommended for use in pregnant or breastfeeding women. Before starting semaglutide, it is important to undergo a thorough evaluation by a healthcare provider to determine if this medication is appropriate for you.
Conclusion
In conclusion, semaglutide pills have shown promise in aiding weight loss by reducing appetite and calorie intake. By mimicking the effects of a hormone called GLP-1, semaglutide can help individuals feel fuller and more satisfied after meals, leading to decreased food cravings and weight loss. While semaglutide is not without potential side effects and contraindications, it can be a valuable tool for individuals looking to achieve and maintain a healthy weight. If you are interested in trying semaglutide for weight loss, be sure to consult with your healthcare provider to determine if this medication is right for you.
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French Pharma Firm Convicted Of Manslaughter Over Weight Loss Pill Deaths
In this episode, Thu and Saley dive deep into the drama surrounding GLP-1 receptor agonist medications like Ozempic and Mounjaro. They explore the meteoric rise of these drugs, fueled by celebrity use for weight loss, and the resulting shortages that have led to a clash between pharmaceutical companies, compounding pharmacies, and the FDA.
The hosts examine the complex issues at play, including the high costs of these medications, the dangers of improper use and dosing, and the challenges patients face in accessing these potentially life-changing treatments. They also shine a light on the concerning trend of med spas prescribing these drugs for cosmetic purposes, putting patients at risk. With their signature blend of expertise, humor, and passion for healthcare, Thu and Saley navigate the nuances of this evolving situation, offering insights and advice for both patients and providers. This episode is a must-listen for anyone interested in the intersection of pharmacy, public health, and the ever-changing landscape of modern medicine.
Here are 5 key takeaways from the episode:
1. GLP-1 receptor agonists have become a social phenomenon, with celebrities fueling a surge in demand for these medications for weight loss, leading to drug shortages.
2. Compounding pharmacies have stepped in to fill the supply gap, but this has raised safety concerns from pharmaceutical companies about the quality and dosing of compounded versions.
3. The FDA has issued warnings about dosing errors and adverse events associated with compounded GLP-1 medications, highlighting the need for proper medical oversight and patient education.
4. The high cost of these drugs, coupled with limited insurance coverage for weight loss indications, has created an experimental situation, with patients seeking alternatives like sublingual formulations without sufficient evidence.
5. The fragility of the drug supply chain and the competing interests of pharmaceutical companies, compounding pharmacies, and regulatory bodies have created a complex situation that requires transparency, collaboration, and a focus on patient safety.
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Chapters
00:00 Intro
3:33 GLP1 background
16:29 Drama begins
22:24 Compounding pharmacy claps back
29:52 FDA enters the chat
41:43 Should you trust compounded GLP1?
56:32 Med spas and GLP1...
1:02:40 Drug shortage and its consequences
•••••••••••••••••••••••••••••••••••••••••••••••••••
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Weight Loss By The Numbers
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Tirzepatide Vs Semaglutide For Weight Loss A Comparison