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Over a quarter of the Indian adult population is either obese, at risk of diabetes or are diabetic. This has become a marketing & business opportunity for a lot of fitness & healthtech companies with plain vanilla no science interventions focussed on either high protein, calorie counting, CGM driven or at worst GLP-1 drugs. But these companies fail to understand how human biochemistry works. These interventions, if they help in weight loss, is a stop gap arrangement. Weight gain is not the cause but the effect & symptom. Obesity is triggered by low grade chronic inflammation & our body tries its best to maintain a metabolic homeostasis. However, regular insults we do to our body by consuming toxins or ingesting those foods that are transformed by your microbiome into toxins or pro-inflammatory metabolites makes it hard for us to lose weight. Some of these metabolites include LPS, TMAO, P-cresol & more. While microbes living in our mouth & gut also produce certain beneficial metabolites & incretin hormones ( providing we are feeding them with the right food substrates) that maintain our metabolic health & make it hard for us to gain weight. One of the most important metabolites ( incretin hormone) is GLP-1. Yes, our body automatically produces GLP-1 by synthesising fibre & polyphenols in the food we eat. GLP-1 has multiple benefits via regulating various metabolic pathways-regulates blood sugar response, communicates with brain via gut-brain axis , telling that you are full & even tells stomach & intestine to slow the movement of digestive tract. However, these GLP-1 drugs which lot of companies claim mimics natural GLP-1 brings multiple side effects & just ingesting these drugs does not mean it will help you lose weight. -Effectiveness of GLP-1 drugs depends upon the functions of your microbiome. Certain microbes can synthesise these drugs into beneficial stuff that have positive correlation with glycemic reduction while some others if active & expressing virulence genes can interfere with synthesis of GLP-1 drugs . -Certain microbes if active & expressing virulence genes can degrade GLP-1, making you gain weight or develop type 2 diabetes. In such scenario, these drugs cannot help. -It has been found that obese have underexpressed NOS attributed to overexpression of tumour necrosis factor-α caused by microbial derived endotoxin LPS. Besides, there are multiple other factors that can suppress NOS/cause endothelial cell dysfunction such as overexpression of ADMA, oxidative stress( caused by P-cresol &/or Indoxyl Sulphate Production), TMAO & more. In order to understand the root cause of obesity, there is a need to understand multiple molecular pathways that trigger its onset/progression. We at Genefitletics measures these pathways to construct nutritional therapeutics interventions aligned with your biochemistry that reinstates yout metabolic homeostasis Citations https://pmc.ncbi.nlm.nih.gov/articles/PMC4112002/ https://pmc.ncbi.nlm.nih.gov/articles/PMC7021470/ https://dom-pubs.pericles-prod.literatumonline.com/doi/10.1111/dom.14725 https://pmc.ncbi.nlm.nih.gov/articles/PMC10391832/ https://diabetesjournals.org/care/article/33/2/453/27096/GLP-1-Based-Therapy-for-Diabetes-What-You-Do-Not https://pmc.ncbi.nlm.nih.gov/articles/PMC5082693/ #obesity #obesityfreeindia #obesityfreenation #obesityawareness #viralvideo #virlshort #viralreels #viral_video #viralshorts #viralnews #healthnews #healthtips #health #healthylifestyle #supplements #obesitymedicine #obesityprevention #obesityawareness #type2diabetes #diabetesawareness #diabetesmanagement #diabetescare #diabetescure

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The ketogenic diet has been gaining popularity in recent years for its numerous health benefits, including weight loss, improved mental clarity, and increased energy levels. This high-fat, low-carbohydrate diet has been endorsed by celebrities and fitness enthusiasts alike, leading to a surge in interest from the general public.

The Ketogenic Diet and Shark Tank

One of the major factors that contributed to the widespread adoption of the ketogenic diet is its feature on the hit TV show Shark Tank. The ketogenic diet was pitched to the investors on the show as a revolutionary way to lose weight and improve overall health. The Sharks were impressed by the science behind the diet and its potential to change lives, leading to a surge in popularity for the ketogenic diet.

Through its exposure on Shark Tank, the ketogenic diet gained mainstream attention and sparked a wave of interest from people looking to improve their health and lose weight. The endorsement from the Sharks lent credibility to the diet and helped dispel misconceptions about the safety and effectiveness of a high-fat diet.

Many viewers of Shark Tank were inspired by the success stories of entrepreneurs who had used the ketogenic diet to transform their health and bodies. This led to a surge in interest in the diet, with many people eager to reap the same benefits that had been showcased on the show.

The Science Behind the Ketogenic Diet

The ketogenic diet is based on the principle of ketosis, a metabolic state in which the body burns fat for fuel instead of carbohydrates. By drastically reducing carbohydrate intake and increasing fat consumption, the body shifts into ketosis and begins to burn stored fat for energy. This leads to rapid weight loss and improved body composition.

Research has shown that the ketogenic diet can be effective for weight loss, as well as improving markers of health such as blood sugar levels, cholesterol, and blood pressure. The diet has also been used to treat neurological disorders such as epilepsy, Alzheimer’s disease, and Parkinson’s disease, with promising results.

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One of the key benefits of the ketogenic diet is its ability to control hunger and cravings, making it easier for people to stick to their diet and achieve their weight loss goals. By stabilizing blood sugar levels and reducing insulin resistance, the ketogenic diet helps to regulate appetite and prevent overeating.

Tips for Success on the Ketogenic Diet

When starting the ketogenic diet, it’s important to focus on whole, nutrient-dense foods such as meat, fish, eggs, nuts, seeds, vegetables, and healthy fats like avocado and olive oil. Avoid processed foods, grains, sugars, and artificial sweeteners, as these can hinder your progress on the diet.

It’s also important to stay properly hydrated and electrolyte-balanced while on the ketogenic diet, as the body excretes more water and sodium when in ketosis. Drink plenty of water and consider supplementing with electrolytes to prevent dehydration and maintain optimal performance.

Tracking your food intake and monitoring your ketone levels can help you stay on track and ensure you’re in ketosis. There are many apps and devices available that can help you track your progress and make adjustments to your diet as needed. Consistency and patience are key to success on the ketogenic diet, so stick with it and trust the process.

Conclusion

The ketogenic diet’s popularity has soared in recent years, due in part to its feature on Shark Tank and the endorsement of the show’s investors. The diet’s numerous health benefits and potential for weight loss have made it a favorite among celebrities, athletes, and everyday individuals looking to improve their health. By following the principles of the ketogenic diet and staying disciplined in your approach, you can achieve your health and weight loss goals and experience the transformative power of this revolutionary way of eating.