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Learn more about becoming an Insider: https://www.benbikman.com
Dr. Bikman’s Metabolic Classroom lecture this week explores the physiological role and implications of GLP-1 (glucagon-like peptide-1) and the GLP-1 receptor agonist drugs used for type 2 diabetes management and weight loss.
Ben begins by explaining GLP-1 as a hormone produced in the intestines in response to food. It plays a vital role in slowing gastric emptying, suppressing glucagon, and regulating appetite by signaling fullness to the brain. These mechanisms contribute to its effects on stabilizing blood sugar and enhancing insulin sensitivity.
He then delves into GLP-1 receptor agonists, drugs that mimic GLP-1’s actions, including semaglutide, liraglutide, and others marketed under brand names like Ozempic and Wegovy. These medications have gained fame for their weight loss efficacy, often leading to reductions in body weight by 15% or more.
However, Ben emphasizes that weight loss involves not only fat but also lean mass, raising concerns about muscle loss and metabolic health. Additionally, he discusses the medications’ side effects, including depression, anhedonia, and potential long-term complications like fat cell development and gallstones.
The lecture also addresses the diminishing returns of these drugs over time, noting that their efficacy in reducing cravings and improving eating control tends to wane after prolonged use. Dr. Bikman highlights that education on healthy eating and resistance training is crucial for maintaining health outcomes, as reliance solely on medication can lead to unintended consequences, such as increased fat regain after discontinuation.
Ben concludes by stressing the importance of combining these drugs with a low-carb diet and resistance training to minimize muscle loss and optimize long-term outcomes. He encourages using the lowest effective dose and underscores the need for lifestyle changes to complement pharmacological interventions.
Show Notes/References:
For complete show notes and references referred to in this episode, we invite you to become a Ben Bikman Insider subscriber. As a subscriber, you’ll enjoy real-time, livestream Metabolic Classroom access which includes live Q&A with Ben, ad-free Metabolic Classroom Podcast episodes, show notes and references, Ben’s Research Reviews Podcast, and a searchable archive that includes all Metabolic Classroom episodes and Research Reviews. Learn more about becoming an Insider on our website: https://www.benbikman.com
(Auto-Translate Note: You can click the gear icon at the bottom of this video to auto-translate captions. For example, to translate into Polish, select Subtitles, choose Auto-Translate, then first choose English, then choose Auto-Translate again, then choose Polish.)
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Timestamps:
00:01 - Introduction and Overview
02:16 - What is GLP-1?
03:15 - GLP-1's Role in Metabolism
05:08 - Appetite Regulation and Insulin Effects
07:05 - GLP-1 and Blood Sugar Management
08:10 - Introduction to GLP-1 Receptor Agonists
09:05 - Key GLP-1 Drugs and Brand Names
12:04 - Weight Loss Mechanisms of GLP-1 Drugs
14:06 - Mental Health Risks of GLP-1 Drugs
16:15 - Muscle Loss Concerns
18:24 - Fat Cell Differentiation and Regain Risk
20:07 - Long-Term Diminishing Effects
25:30 - Pancreatitis and Gallstones
29:11 - Closing Thoughts and Recommendations
Ben’s favorite yerba maté and fiber supplement: https://ufeelgreat.com/usa/en/c/1BA884
Ben’s favorite meal-replacement shake: https://gethlth.com (discount: BEN10)
Ben’s favorite electrolytes (and more): https://redmond.life (discount: BEN15)
Ben’s favorite allulose source: https://rxsugar.com (discount: BEN20)
Ben’s favorite health check-up for women: https://choosejoi.co/drben15 (discount: DRBEN15)
Ben’s favorite health check-up for men: https://blokes.co/drben15 (discount: DRBEN15)
Ben’s favorite exogenous ketone: https://www.americanketone.com (discount: Ben10)
Other products Ben likes: https://www.amazon.com/shop/benbikmanphd
Learn more about becoming an Insider on our website: https://www.benbikman.com
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Hello Everyone,
Ballerina, Food, and the Power of Words 🩰🥣
In this episode, we’re unpacking a topic that so many dancers silently struggle with: food, body image, and the influence of language in ballet.
Even though I adored my teachers with my whole heart, some of them came from an older generation, where the belief was that every ballerina should be one weight, and no higher. One comment, one look, one word can shift how you view yourself and your relationship with food for years to come.
We’ll talk about how those comments affected us, how we coped as young dancers, and what the food culture was actually like at the Vaganova Academy. Was it strict? Was it unhealthy? Or was it surprisingly different to what you might imagine?
This episode is for every dancer who’s ever questioned their worth because of a number, and for anyone who’s ready to create a healthier, more compassionate mindset around food and ballet.
🎧 Tune in to feel supported, seen, and reminded that you are so much more than your weight.
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✨ Welcome to Ballet With Isabella! ✨
https://balletwithisabella.com
Ballet With Isabella (BWI) is your go-to online training platform for dancers of all levels! Whether you’re a beginner, pre-professional, or pro, we help you refine your technique, build strength, and boost confidence all with structured training that delivers real results. We are a community of go getters!
💖 What You’ll Find Here:
✅ Expert-led ballet classes & courses
✅ On-demand classes and courses to watch wherever you are.
✅ Structured Plans
✅ Flexibility & strength workouts for dancers
✅ Mindset coaching
✅ Live Zoom classes for Members ( recorded to watch later)
✅ Private coaching & personalized plans to smash your goals
✅ Intensives worldwide to work with isabella face to face.
💡 Join Our Membership!
🔹 Corps – Recorded classes + Live Members Classes
🔹 Soloist – Live Classes + all on-demand classes & courses & plans
🔹 Principal – Everything + a custom plan every 8 weeks
🎙️ Listen to Our Podcast! A Dancer’s Mindset (Co-hosted by Suvi Honkanen) – interviews, training tips, and mental strategies to help you succeed in ballet.
👩🏫 About Isabella
Isabella is a graduate of vaganova, pro ballet dancer and professional ballet coach. Founder of BWI, she beleives everyone should have the best. Helping dancers worldwide reach their full potential through expert training & mindset coaching.
🔗 Start Training Today! → https://balletwithisabella.com/select-a-plan/
✨ Subscribe & turn on notifications for new ballet content every week! 💃🩰
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