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🔥GLP-1 Meds Linked to Stomach Paralysis?🔥 Doctors claim they’re safe, but thousands report gastroparesis, a life-threatening condition 😨 In this video: ✔️What it is & why it’s dangerous 🚨 ✔️1,400+ lawsuits filed ⚖️ ✔️Natural weight loss that protects your gut 🌱 Before you risk your health, watch this first! 🎥👇 📺 Click here to watch: https://youtu.be/Ln3wZSzk63o?si=u5-NEscYDvEdw8u4 #MounjaroSideEffects #ZepboundSideEffects #GLP1Dangers #WeightLossDrugs
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💉 Ozempic Nation – The Drug That’s Taking Over Hollywood In this shocking episode of Celebrity Down-Sizing, we explore the rise of Ozempic and Wegovy — the weight loss injections reshaping not only bodies but also the rules of beauty in Hollywood. ⚠️ What's inside: – Why stars are secretly using diabetes medication to slim down – How Hollywood glam hides a dangerous shortcut – The real cost of rapid weight loss – What Ozempic says about our obsession with thinness and perfection – Shocking before-and-after celeb transformations 🌟 It's not just about health — it's about status, speed, and control. 💊 Is Ozempic the miracle Hollywood wanted... or the monster it created? 👇 Let us know: Would you ever take Ozempic just to lose weight? Where do we draw the line between wellness and image? 🔔 Subscribe for more pop culture psychology, celebrity breakdowns & shocking truths. #Ozempic #CelebrityDownsizing #HollywoodWeightLoss #Wegovy #PopCulture #CelebrityGlowUp #Shorts #Viral
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GLP1 drugs are highly effective at weight loss, but it comes at a cost. The approach requires expertise and oversight from an expert. There are several strategies that can help prevent or manage muscle mass loss associated with GLP-1 agonist treatment: ## Resistance Training Incorporating resistance or strength training exercises is one of the most effective ways to preserve and build muscle mass during weight loss[1][2]. This counteracts the catabolic effects of caloric deficit by stimulating muscle protein synthesis. ## Adequate Protein Intake Ensuring sufficient dietary protein intake, ideally 1.6-2.2 g/kg of ideal body weight per day, can help minimize muscle loss[2]. Protein provides amino acids needed for muscle maintenance and repair. ## Combining with Myostatin Inhibitors Myostatin is a key negative regulator of muscle growth. Blocking myostatin with investigational drugs like apitegromab (SRK-439) from Scholar Rock may enhance muscle growth and prevent muscle loss when combined with GLP-1 agonists[1]. Early clinical trials are underway to test this approach. ## Using Activin Receptor Inhibitors Activin receptor inhibitors like those being developed by companies like Regeneron can block activin signaling and potentially increase muscle mass when used alongside GLP-1 medications[3]. ## mTOR Activators The mTOR pathway regulates muscle protein synthesis. Drugs that activate mTOR, such as the PPAR agonist enobosarm being tested by Veru, may preserve muscle when combined with GLP-1 treatment[5]. ## Adequate Vitamin D and Calcium Ensuring sufficient vitamin D and calcium intake is important for preserving bone mineral density, which can be impacted by the weight loss and muscle loss induced by GLP-1 agonists[2]. The key is utilizing a multi-modal approach combining GLP-1 agonists with resistance exercise, optimal nutrition, and emerging muscle-preserving medications to maximize fat loss while minimizing the loss of metabolically active lean muscle mass[1][2][3]. Citations: [1] https://pharmanewsintel.com/features/addressing-muscle-loss-associated-with-glp-1-medication-use [2] https://www.medscape.com/viewarticle/994030 [3] https://www.tctmd.com/news/dont-worry-about-muscle-loss-glp-1-inhibitors-viewpoint-asserts [4] https://www.uclahealth.org/news/article/rapid-weight-loss-can-lead-loss-muscle-mass [5] https://www.drugdiscoverytrends.com/glp-1-impact-lean-mass/
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Are GLP-1 weight loss drugs the solution we've been waiting for—or just another manifestation of diet culture in disguise? In this episode 42, "GLP-1 Medications Explained: What You Need to Know in 2025," of the How to Fitness Podcast, we dive into the hype, hope, and hard truths surrounding medications like Ozempic and Wegovy. Join us as we break down the science behind GLP-1 drugs, discuss their benefits for obesity and metabolic health, and explore the potential risks and ethical dilemmas tied to their use. From celebrity endorsements to compounding pharmacies and societal pressures, this episode uncovers the complexities of these groundbreaking yet polarizing treatments. Tune in to get the facts, hear real-world insights, and learn how to navigate this evolving topic with clarity. TIMESTAMPS: 00:00 Introduction and Personal Opinions on Weight Loss Medications 00:23 Welcome to the How to Fitness Podcast 01:07 Revisiting the Ozempic Revolution 03:04 Understanding GLP-1 Medications 04:19 Mechanisms and Effects of Semaglutide 07:00 Personal Experiences and Observations 10:22 The Broader Impact and Misconceptions 20:34 Celebrity Influence and Public Perception 23:16 Exploring Telehealth and Accessibility 23:57 Exploring Telehealth Weight Loss Options 28:15 Compounding Pharmacies: Pros and Cons 29:58 The Risks of Compounded Medications 34:22 The Social Implications of Weight Loss Drugs 39:33 Long-Term Use and Ethical Considerations RESOURCES MENTIONED: 🟡 The Ozempic Revolution: Exploring the Soaring Popularity of GLP-1 Drugs https://www.buzzsprout.com/2171581/episodes/12924933 🟡 What are "GLP1 Agonists"? https://glp1.guide/content/what-are-glp1-agonists/ 🟡 GLP‐1 signaling in the brain https://pmc.ncbi.nlm.nih.gov/articles/PMC8820188/?ref=glp1.guide 🟡 FDA’s ongoing evaluation of reports https://www.fda.gov/drugs/drug-safety-and-availability/update-fdas-ongoing-evaluation-reports-suicidal-thoughts-or-actions-patients-taking-certain-type?ref=glp1.guide 🟡 Drug ad spending https://www.cnbc.com/2024/04/03/weight-loss-diabetes-drug-ad-spending-tops-1-billion.html 🟡 GLP-1 Adverse Events https://www.mdpi.com/1424-8247/17/2/199?ref=glp1.guide 🟡 FDA’s Concerns with Unapproved GLP-1 Drugs Used for Weight Loss https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/fdas-concerns-unapproved-glp-1-drugs-used-weight-loss 🟡 Once-Weekly Semaglutide in Adults with Overweight or Obesity https://www.nejm.org/doi/full/10.1056/NEJMoa2032183 🟡 The New Yorker https://www.newyorker.com/magazine/2023/03/27/will-the-ozempic-era-change-how-we-think-about-being-fat-and-being-thin Listen to our How to Fitness podcast on your favorite platform! https://howtofitness.buzzsprout.com/2171581/episodes We’d love to hear your thoughts! Share your feedback or questions in the comments below! And while you’re here, don’t forget to subscribe to our podcast and hit that notification bell so you never miss an episode. STAY CONNECTED 🟡 Michael Ulloa: https://www.michaelulloa.com/ Instagram: https://www.instagram.com/michaelulloapt 🟡 Kate Lyman: https://www.katelymannutrition.com/ Instagram: https://www.instagram.com/klnutrition/ Thank You for Listening to How to Fitness Podcast with Michael Ulloa and Kate Lyman! #howtofitness #howtofitnesspodcast #healthandfitnesspodcast #bustingnutritionmyth
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