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Dr. James Hill—a expert on obesity, metabolism, and long-term weight management—joins me this week to unpack the biggest challenges in sustainable fat loss. Dr. Hill has spent decades researching weight control and the factors that determine whether people can keep weight off long-term. We discuss the science behind energy balance, metabolic flexibility, and why long-term weight loss is about more than just diet and exercise. He shares insights from his groundbreaking work with the National Weight Control Registry, the role of GLP-1 medications, and why physical activity is the key to preventing weight regain. We cover: The critical differences between weight loss and weight maintenance Why physical activity is perhaps more important for keeping weight off than losing it The National Weight Control Registry: lessons from long-term weight loss success stories How metabolism, muscle mass, and energy expenditure affect weight regain The role of protein and resistance training in preserving lean mass The impact of GLP-1 medications on weight loss and why most people regain weight after stopping them The psychology of weight maintenance: mindset, self-monitoring, and behavior change If you’ve ever struggled to keep weight off, or you’re interested in the latest research on metabolic health and sustainable weight management, this episode is a must-listen. Who is Dr. James Hill? Dr. James Hill is an internationally recognized expert on obesity, metabolism, and weight management. He is the co-founder of the National Weight Control Registry, the largest ongoing study tracking individuals who have successfully lost weight and kept it off long-term. Dr. Hill has published over 400 scientific articles and has led pioneering research on energy balance, metabolic flexibility, and the role of physical activity in weight maintenance. He is a professor at the University of Alabama at Birmingham and has served as the President of The Obesity Society. His work has been instrumental in shaping modern obesity treatment and prevention strategies. This episode is brought to you by: Puori - Code DRLYON for 20% off sitewide!– https://Puori.com/DRLYON Cozy Earth - Code DRLYON for up to 40% off! – https://cozyearth.com/DRLYON BON CHARGE - Code DRLYON for 15% off! - https://boncharge.com/DRLYON Manukora- Get $25 off the Starter Kit at https://manukora.com/DRLYON Find Dr. James Hill at: International Weight Control Registry https://internationalweightcontrolregistry.org/ Scholars Profile - https://scholars.uab.edu/6698-james-hill Academic Website - https://www.uab.edu/norc/about-us/leadership/executive-committee/james-hill Find me at: Instagram: @drgabriellelyon TikTok: @drgabriellelyon Facebook: facebook.com/doctorgabriellelyon YouTube: youtube.com/@DrGabrielleLyon X: x.com/drgabriellelyon Apply to become a patient - https://drgabriellelyon.com/new-patient-inquiry/ Join my weekly newsletter - https://institute-for-muscle-centric-medicine.ck.page Get my book - https://drgabriellelyon.com/forever-strong/ Forever Strong Summit 2025 - Grab your ticket NOW before we sell out! https://drgabriellelyon.com/forever-strong-summit-2025/ Timestamps: 00:00 - Intro & Forever Strong Summit Announcement 02:21 - Meet Dr. James Hill 04:34 - Why obesity wasn’t always a major concern 08:12 - The truth about energy balance and weight loss 14:42 - Weight loss vs. weight maintenance: why they require different strategies 18:01 - Why food restriction works for weight loss but fails for maintenance 24:04 - The role of dietary protein and resistance training in weight loss 30:17 - How small changes in energy balance lead to big results 35:07 - Why 150 minutes of exercise per week isn’t enough to maintain weight loss 41:55 - Why most people regain weight after stopping GLP-1 medications 48:00 - How metabolic flexibility influences weight control 52:47 - The importance of tracking body composition over time 1:02:00 - Why exercising your metabolism is key to long-term success 1:09:14 - The underestimated role of mindset in weight management 1:18:27 - The future of obesity treatment: personalized approaches Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

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When it comes to weight loss, there are countless options available in the market, including diet plans, exercise routines, and weight loss pills. Among these, FDA approved weight loss pills have gained popularity as they are perceived to be safe and effective. However, it is essential to understand the safety and effectiveness of these pills before incorporating them into your weight loss journey.

Understanding the Safety of FDA Approved Weight Loss Pills

Before a weight loss pill can be approved by the Food and Drug Administration (FDA), it undergoes rigorous testing to ensure its safety. These tests evaluate the potential side effects of the pill and how it interacts with other medications. Additionally, the FDA monitors the pill’s safety after it hits the market, taking action if any concerning reports surface. This stringent process provides a level of assurance regarding the safety of FDA approved weight loss pills.

It is essential to remember that while FDA approved weight loss pills are deemed safe for consumption, they may still have side effects. Common side effects include nausea, constipation, headaches, and dizziness. It is crucial to consult with a healthcare professional before starting any weight loss pill to understand potential risks and ensure it is the right choice for you.

Furthermore, it is crucial to follow the recommended dosage and usage instructions provided with the weight loss pill. Taking more than the recommended amount can lead to adverse effects and negate any potential benefits. Additionally, combining multiple weight loss pills or using them alongside other medications without consulting a doctor can be dangerous.

Evaluating the Effectiveness of FDA Approved Weight Loss Pills

While FDA approved weight loss pills are considered safe, their effectiveness varies from person to person. It is essential to manage expectations and understand that these pills are not a magic solution for weight loss. They are designed to complement a healthy diet and regular exercise routine, enhancing your efforts rather than replacing them entirely.

When evaluating the effectiveness of a weight loss pill, look for scientific studies and clinical trials that support its claims. These studies provide insight into how the pill works, its impact on weight loss, and any potential benefits. Additionally, real-life testimonials from users can offer a perspective on the pill’s effectiveness beyond the data presented in studies.

It is important to approach FDA approved weight loss pills with a realistic mindset and be wary of products that promise drastic results with minimal effort. Sustainable weight loss requires commitment, dedication, and a holistic approach that includes not only the use of weight loss pills but also healthy lifestyle choices.

Navigating the World of FDA Approved Weight Loss Pills

With numerous FDA approved weight loss pills available in the market, it can be overwhelming to choose the right one for your needs. To make an informed decision, research different pills, their ingredients, and potential side effects. Consult with a healthcare professional to discuss your weight loss goals and determine the most suitable option for you.

When selecting a weight loss pill, consider factors such as your current health status, medical history, and any existing conditions. Certain weight loss pills may be contraindicated for individuals with specific health issues or medications. It is crucial to disclose all relevant information to your healthcare provider to ensure a safe and effective weight loss journey.

Remember that FDA approved weight loss pills are just one tool in your weight loss arsenal. Alongside the use of these pills, focus on maintaining a balanced diet, staying active, and practicing healthy habits that support your overall well-being. By combining these efforts, you can increase the likelihood of achieving sustainable weight loss results. Chia Seeds Are Good For Your Gut Health Chiaseeds Weightloss Food Health

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WHO backs weight-loss drugs — but pharma pricing sparks concern. 💰 Can low-income nations afford this breakthrough treatment? Want the full update? Watch the complete video on our channel. This is part of our PulseNow updates. 🌟 Stay tuned. One scroll, one heartbeat at a time. Watch. Learn. Share. Subscribe now — and start feeling what’s now. @PulseNowChannel #PulseNow #PharmaWatch #ObesityTreatment #GlobalInequality #HealthAccess #GLP1Drugs #WHO

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