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Discussing common hacks you can do on a daily basis to prime your metabolic rate to burn fat.
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Dr. Palaniappan Manickam MD, MPH
Internal Medicine | Gastroenterology | Epidemiologist
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Metformin is an oral medication commonly used to manage type 2 diabetes mellitus. It is often the first-line treatment due to its effectiveness, safety profile, and additional benefits beyond blood sugar control.
Mechanism of Action
Metformin primarily works by:
Reducing Hepatic Glucose Production**: It decreases the amount of glucose produced by the liver, particularly by inhibiting gluconeogenesis (the process of generating glucose from non-carbohydrate sources).
Increasing Insulin Sensitivity**: Metformin enhances the sensitivity of peripheral tissues (like muscle and fat) to insulin, facilitating better uptake of glucose from the bloodstream.
Decreasing Intestinal Absorption of Glucose**: It may also reduce the absorption of glucose from the gastrointestinal tract.
Indications
Metformin is indicated for:
Type 2 Diabetes Mellitus**: It is used to improve glycemic control in adults and children (larger than & equal to 10 years), typically in conjunction with diet and exercise.
Polycystic Ovary Syndrome (PCOS)**: Off-label, it is sometimes used to manage symptoms related to insulin resistance in women with PCOS.
Dosage and Administration
Formulations**: Metformin is available in immediate-release and extended-release formulations.
Dosing**: The initial dose is usually low, gradually increased based on tolerance and glycemic control. The maximum dose typically does not exceed 2,000-2,500 mg per day, depending on the formulation.
Side Effects
Common side effects include:
Gastrointestinal issues: Nausea, vomiting, diarrhea, abdominal discomfort, and flatulence (often transient).
Lactic acidosis: A rare but serious side effect, particularly in individuals with renal impairment or contraindicating conditions.
Contraindications
Metformin is contraindicated in:
Severe renal impairment (eGFR less than 30 mL/min)
Acute or chronic metabolic acidosis, including diabetic ketoacidosis
Hypersensitivity to metformin
Cautions
Renal Function Monitoring**: Kidney function should be assessed before starting therapy and regularly monitored during treatment.
Use in Specific Populations**: Caution is advised in patients with liver disease, heart failure, or those undergoing procedures involving contrast media, as these can increase the risk of lactic acidosis.
Benefits Beyond Glycemic Control
Metformin has additional benefits, including:
Weight Management** It is generally weight-neutral or may even promote modest weight loss, making it suitable for overweight individuals with type 2 diabetes.
Cardiovascular Benefits**: Some studies suggest that metformin may have cardiovascular protective effects.
Conclusion
Metformin is a cornerstone in the management of type 2 diabetes, known for its efficacy in lowering blood sugar levels, safety profile, and additional health benefits. As with any medication, it should be prescribed and monitored by a healthcare professional, ensuring that patients receive the most appropriate and effective treatment for their condition. Regular follow-up and lifestyle modifications (diet and exercise) are essential components of diabetes management alongside metformin therapy.
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✅Key Ingredients in Mitolyn for Weight Support While the specific formula may vary, Mitolyn typically includes: Coenzyme Q10 (CoQ10): Enhances mitochondrial energy production and supports metabolic processes. PQQ (Pyrroloquinoline Quinone): Promotes mitochondrial biogenesis, creating new mitochondria to boost energy production. L-Carnitine: Helps transport fatty acids into mitochondria for energy production, directly aiding fat metabolism. Alpha-Lipoic Acid (ALA): A powerful antioxidant that also supports glucose metabolism.
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The popularity of the ketogenic diet has been on the rise in recent years, as it has proven to be an effective way to lose weight and improve overall health. In addition to following a low-carb, high-fat diet, many people have also been incorporating apple cider vinegar (ACV) into their daily routines for its numerous health benefits. Now, a new product has emerged that combines the power of both keto and ACV into one convenient and delicious form – Keto ACV Pro Max Gummies.
Benefits of Apple Cider Vinegar
Apple cider vinegar has been used for centuries for its various health benefits. It is packed with antioxidants and has been shown to help regulate blood sugar levels, improve digestion, and even aid in weight loss. ACV also has antimicrobial properties and can help lower cholesterol levels. By incorporating ACV into your daily routine, you can support your overall health and well-being.
One of the most notable benefits of ACV is its ability to help with weight loss. The acetic acid in ACV has been shown to increase metabolism, reduce fat storage, and suppress appetite. This can help you reach your weight loss goals faster and more effectively. Additionally, ACV can help balance blood sugar levels, which is essential for maintaining a healthy weight.
ACV is also beneficial for digestion. It can help improve gut health by promoting the growth of good bacteria and aiding in digestion. This can help reduce bloating, gas, and other digestive issues. By incorporating ACV into your daily routine, you can support a healthy digestive system and overall gut health.
Benefits of Keto
The ketogenic diet is a low-carb, high-fat diet that has been shown to be effective for weight loss, managing blood sugar levels, and improving overall health. By reducing carbohydrate intake and increasing fat consumption, the body enters a state of ketosis, where it burns fat for fuel instead of carbohydrates. This can lead to rapid weight loss and increased energy levels.
In addition to weight loss, the ketogenic diet has been shown to have numerous other health benefits. It can help lower inflammation, improve cognitive function, and even reduce the risk of certain chronic diseases. By following a keto diet, you can support your overall health and well-being in a number of ways.
One of the key benefits of the ketogenic diet is its ability to regulate blood sugar levels. By reducing carbohydrate intake and increasing fat consumption, the body is able to maintain stable blood sugar levels throughout the day. This can help prevent energy crashes, reduce cravings, and improve overall energy levels. By following a keto diet, you can support healthy blood sugar levels and reduce the risk of developing insulin resistance and type 2 diabetes.
Keto ACV Pro Max Gummies: The Ultimate Combination
With Keto ACV Pro Max Gummies, you can now enjoy the benefits of both apple cider vinegar and the ketogenic diet in one convenient and delicious form. These gummies are made with high-quality ingredients, including organic apple cider vinegar, MCT oil, and collagen, to provide maximum health benefits. By incorporating these gummies into your daily routine, you can support weight loss, improve digestion, and boost overall health.
These gummies are easy to incorporate into your daily routine. Simply take the recommended dosage each day to enjoy the benefits of apple cider vinegar and the ketogenic diet. Whether you’re looking to lose weight, improve digestion, or support overall health, Keto ACV Pro Max Gummies are a convenient and tasty way to achieve your health goals.
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In conclusion, Keto ACV Pro Max Gummies are a powerful combination of apple cider vinegar and the ketogenic diet that can help you achieve your health goals. By incorporating these gummies into your daily routine, you can enjoy the benefits of both ACV and keto in one convenient and delicious form. Whether you’re looking to lose weight, improve digestion, or boost overall health, these gummies are a convenient and effective way to support your health and well-being.
Overall, Keto ACV Pro Max Gummies combine the power of apple cider vinegar and the ketogenic diet to provide maximum health benefits. By incorporating these gummies into your daily routine, you can support weight loss, improve digestion, and boost overall health. If you’re looking for a convenient and delicious way to achieve your health goals, Keto ACV Pro Max Gummies are the perfect solution.
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Chapters
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00:00 What is heart rate variation?
00:46 : Zone 1 Cardio
1:43 Zone 2 cardio
3.09 Zone 3 cardio
07:11 Final thoughts
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Heart rate zone training is essential for effective fat loss. If you're not achieving the results you desire, understanding and utilizing different heart rate zones can make a significant difference. In this discussion, we will explore three key zones: the resting heart rate zone, the fat loss zone, and the fitness heart rate zone.
The resting heart rate zone is crucial for recovery and overall cardiovascular health. By knowing your resting heart rate, you can better gauge your fitness level and recovery progress.
Next, we will delve into the fat loss zone, which is typically between 60-70% of your maximum heart rate. Training in this zone is particularly effective for burning fat, as your body utilizes fat as the primary source of energy during moderate-intensity workouts.
Finally, we will examine the fitness heart rate zone, usually ranging from 70-85% of your maximum heart rate. This zone helps improve cardiovascular endurance and overall fitness, making it vital for those looking to enhance their athletic performance alongside fat loss.
After watching this episode, you will be equipped with the knowledge to train at the optimal heart rate zones, allowing you to maximize your fat loss efforts and achieve your fitness goals more effectively..
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