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In this episode, Dr. Craig Koniver, M.D., a board-certified physician trained at Brown University and Thomas Jefferson University, discusses the therapeutic application of peptides and hormones for enhancing physical and mental health and performance. We explore GLP-1 analogs for weight loss, BPC-157 for wound healing and reducing inflammation, as well as peptides that increase growth hormone, improve REM sleep, and enhance cognitive function. We also cover testosterone therapy, NAD, NMN, and NR supplementation, methylene blue for mitochondrial health, stem cell therapies, and supplements such as CoEnzyme Q10 and methylated B vitamins. Additionally, we discuss effective dosages, sourcing, safety considerations, and the importance of working with knowledgeable physicians. Whether you're currently using peptides or exogenous hormones, or simply curious about their potential benefits and risks, this episode provides the scientific rationale behind how peptides function, their potential to enhance mental and physical health, and how they can optimize performance. Access the full show notes for this episode: https://go.hubermanlab.com/Nya6k2f Pre-order Andrew's book, Protocols: https://go.hubermanlab.com/protocols Use Ask Huberman Lab, our chat-based tool, for summaries, clips, and insights from this episode: https://go.hubermanlab.com/tqqZoQT *Thank you to our sponsors* AG1: https://drinkag1.com/huberman Joovv: https://joovv.com/huberman BetterHelp: https://betterhelp.com/huberman Function: https://functionhealth.com/huberman Eight Sleep: https://eightsleep.com/huberman *Huberman Lab Social & Website* Instagram: https://www.instagram.com/hubermanlab Threads: https://www.threads.net/@hubermanlab Twitter: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://www.hubermanlab.com Newsletter: https://www.hubermanlab.com/newsletter *Dr. Craig Koniver* Koniver Wellness: https://koniverwellness.com Koniver Aesthetics: https://koniveraesthetics.com Instagram: https://www.instagram.com/koniverwellness LinkedIn: https://www.linkedin.com/in/craig-koniver-md-4bb100126 *Timestamps* 00:00:00 Dr. Craig Koniver 00:04:52 Sponsors: Joovv & BetterHelp 00:07:40 What is a Peptide? 00:09:37 GLP-1 Agonists, Semaglutide Weight Loss, Brain Health 00:15:49 GLP-1 Microdoses, Muscle Loss; Inflammation 00:18:43 BPC-157, Inflammation 00:23:27 BPC-157, Injection & Oral Forms; Injury Repair 00:28:43 Sourcing, Anabolic Steroids, Testosterone 00:34:48 Black & Gray Market, Compounding Pharmacies, Purity 00:38:20 Sponsor: AG1 00:39:51 Partnering with a Physician, LPS 00:43:00 BPC-157, Pentadeca Arginate (PDA); Side Effects & Doses 00:46:35 Ipamorelin, GHRP-6, Sleep, Appetite; Tool: Sleep & Growth Hormone 00:54:17 Tesamorelin, Sermorelin, CJC-1295; Stacking Peptides 00:58:45 Sponsor: Function & Eight Sleep 01:01:54 Coenzyme Q10 (CoQ10), Mitochondrial Health 01:05:16 Prescriptions, Physicians & Trust 01:14:09 Agency in Your Health 01:17:13 MK-677, Appetite 01:19:32 Hexarelin; Growth Hormone Secretagogues Dosing 01:21:10 Methylated B Vitamins, Homocysteine 01:24:47 Peptides for Sleep, Pinealon, Epitalon 01:31:03 Glycine, Liver Detoxification; Dosage 01:37:19 GLP-1, Compounding Pharmacies 01:39:03 Stem Cell Therapy, PRP 01:41:18 Thymosin Alpha-1, Cerebrolysin & Brain Health 01:44:17 Peptides for Cognitive Function, Methylene Blue, Doses 01:50:20 Covid, NAD Infusion, NMN & NR Supplements 01:57:13 Nutritional Deficiencies; NAD Dose & Regimen, NMN & NR 02:07:53 PT-141, Vyleesi, Libido; Nausea 02:10:57 FDA Approval & Removal, Pharmaceutical Companies 02:20:17 Positivity, Mindset & Health 02:26:23 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter #HubermanLab #Health #Peptides Disclaimer & Disclosures: https://www.hubermanlab.com/disclaimer

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Are you on Ozempic®, Wegovy®, or another GLP-1 med? These drugs are changing lives—but many users aren’t told about the gut side effects. 👉 14% report diarrhea. 7% end up constipated. But it’s not just about symptoms—it’s about why it happens. In this episode, colorectal surgeon Dr. Carmen Fong breaks down what GLP-1s do to your gut: ✔️ Slowed motility ✔️ Increased water absorption ✔️ Decreased appetite ✔️ Reduced nutrient intake This trifecta can mean rock-hard stools, explosive diarrhea, or both—especially when paired with low-fiber meals. 💩 If you’re struggling with bowel habits while on GLP-1s, it’s not just you—and there are ways to support your gut. 🎧 Visit IBSdietitian.com/podcast to listen to the full episode.

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These are some of the best exercises you can do to burn more calories, overall body fat, and reduce your belly fat/love handles faster. Remember that the number one way to lose belly fat is not with a workout, but instead with your diet. However, these fat loss exercises can assist with weight loss and many of these exercises can be done at home. 🔥 FREE 6 Week Shred: https://GravityTransformation.com 📲 FREE Diet/Workout Planner Tool: http://bit.ly/2N41lTX ➡️ Sandbag: https://amzn.to/3vfnfZH ➡️ Beginner At-Home Fat Loss Exercises: https://youtu.be/aENfevT4wco Belly fat and the fat around your midsection, in general, is really easy to gain, but really hard to get rid of, and carrying around excess pounds of body fat is unhealthy and unattractive. So many people take it upon themselves to fix their belly fat problem, and most of them will try to do crunches and situps until the fat disappears. But crunches and situps are some of the worst exercises you can do because they don't burn a lot of calories at all, and unfortunately, you can't target the fat on your midsection by doing ab exercises. So truly the best exercise that you can do to reduce your belly fat is the exercise of self-control when it comes to your diet and what you eat on a daily basis. However, even though your diet will always be the main determining factor for how many calories you take in, there are certain exercises that burn far more calories than others, and these exercises can be used to boost the number of calories you burn on a weekly basis, which will help you burn more fat from your whole body including the fat on your midsection. And the first exercise that I want to start with is a simple medicine ball slam. The easiest way to do this is by using either a slam ball, which looks just like a medicine ball or a sandbag. Since slam balls are becoming more and more common in gyms, I'll be demonstrating with a slam ball. So you're going to start with your feet shoulder-width apart and the ball in between your feet. Squat down, grab the ball, stand up, and curl and press it over your head. Then slam the ball down into the ground as hard as you can, in between your feet. So you don't want to just throw the ball to the ground using only your arms. Instead, when the ball is over your head you want to pull your hips back out from under you and put your whole body into the slam by bending at the waist and using the full power of your core to drive the ball into the ground. then repeat for reps. This same exercise can be done with a sandbag in the same exact way, and if you don't have access to either one, then you can make your own sandbag with the bag that I have linked up in the description, just add sand and you're good to go.  Another great exercise that'll get you really winded is the cable woodchopper. To set this one up you're going to bring the pulley to the bottom of the cable cross and attach a d handle. Then while standing with the D handle at your side, bend down, and grab it with both hands. You can either interlace your fingers or simply put one hand over the other. So this is your starting position, standing straight up with the d -handle in both hands at your side. From there you're going to squat straight down, stand up and with your elbows almost fully locked out, you're going to rotate the cable from your hips at an upward angle over your opposite shoulder. Then, bring the cable back to the starting position, while still keeping your elbows almost fully locked out and repeat for reps on one side before switching to the other. Don't make the mistake of bending and extending your arms on each repetition, this should be a rotational movement. AND keep in mind that most people don't perform exercises that develop rotational strength and this is a big problem because almost all injuries occur when a rotational force is involved. So strengthening with exercises like the woodchop can really help prevent potential injuries.  Next, we have one of the best calorie-burning exercises period, the weighted burpee. To begin you're going to grab two moderately heavy dumbbells that you can curl and press over your head. Then stand straight up with both dumbbells hanging at your sides. Squat down as you bend your back and plant both dumbbells around the outside of your feet. Then jump your feet back, out into a pushup position and perform a pushup onto the dumbbells. After that hop your feet back in between your hands, and stand straight up with the dumbbells. When lifting the dumbbells off the ground you want to do it with good form, as if you're performing a suitcase deadlift. So make sure you maintain the natural curve of your lower back as you stand up. And then curl and press those dumbbells over your head. Finally, lower the dumbbells back to your shoulders, then bring them back to your sides, and repeat for reps. Now if you're a beginner you can do these with just your body weight and instead of jumping your feet out, step ...

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