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When we eat a meal containing carbohydrates a peptide called GLP-1 is released into the blood and acts in several ways to improve glucose regulation. It stimulates insulin release from the pancreas, increases insulin sensitivity, and suppresses appetite. A peptide called exenatide originally discovered in the venom of the Gila monster activates GLP-1 receptors and is now prescribed as a treatment for diabetes and obesity. Preclinical studies at the NIH showed that exenatide prevents neuronal damage and improves functional outcome in experimental models of Parkinson’s and Alzheimer’s diseases. Professor Tom Foltynie at University College London then led clinical trials of exenatide in Parkinson’s disease which demonstrated beneficial effects of exenatide. In this episode I talk with Professor Foltynie about GLP1 receptor agonists and how they protect neurons against damage and dysfunction in Parkinson’s and other neurological disorders.
LINKS
Professor Foltynie’s webpage:
https://www.ucl.ac.uk/ion/research/our-departments/clinical-and-movement-neurosciences/people/prof-t-foltynie
Lancet article: RCT of Exenatide in Parkinson’s disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831666/pdf/nihms939356.pdf
Review articles on GLP1 and its effects on diabetes and obesity
https://www.cell.com/action/showPdf?pii=S1550-4131%2818%2930179-7
Review article on energy metabolism and Parkinson’s disease:
https://content.iospress.com/download/journal-of-parkinsons-disease/jpd130335?id=journal-of-parkinsons-disease%2Fjpd130335
Preclinical studies of Exenatide for:
Parkinson’s disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633544/pdf/zpq1285.pdf
Alzheimer’s disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948479/
Huntington’s disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628604/pdf/318.pdf
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In this video, I discuss my journey with weight gain while taking antipsychotic medication. I share about a period where I gained almost 60 pounds over a very short span of time as a result of the psychiatric medications I was on. I also share how I lost the weight and how I work on maintaining good general health and wellness while on antipsychotic medications.
If you are struggling with weight gain as a side effect of your psychiatric medication, I strongly encourage you to bring it up with your doctor. They should be able to work with you to find something that works better for you in terms of reducing weight gain, or they can help you find alternative means to help maintain a healthy weight.
I also just want to reiterate that, so long as you feel well and healthy, it does not matter how much you weigh. At any weight, you are just as deserving of love and happiness as anyone else or as you at any other weight. Focus on being healthy!
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Dietician Suman Chauhan’s Certification:
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When it comes to satisfying your sweet tooth while still being mindful of your health, apple gummies from Chemist Warehouse may just be the perfect solution. These delicious treats offer the perfect combination of sweetness and tartness, all packed into a convenient and portable form. Made with real apple juice and natural flavors, these gummies provide a guilt-free indulgence that you can enjoy anytime, anywhere. Let’s explore why apple gummies at Chemist Warehouse are a healthy option for those looking to satisfy their cravings without compromising on taste.
The Benefits of Apple Gummies
1. Natural Ingredients: One of the key reasons why apple gummies at Chemist Warehouse are a healthy choice is their use of natural ingredients. Unlike traditional gummies that are loaded with artificial flavors and colors, these gummies are made with real apple juice and natural fruit extracts. This means that you can enjoy the delicious taste of apples without the guilt of consuming unnecessary additives.
2. Low in Calories: Another benefit of apple gummies is their low calorie content. Each serving typically contains fewer calories than traditional candies, making them a great option for those looking to watch their calorie intake. This makes them a great snack option for those looking to satisfy their sweet cravings without overindulging.
3. Rich in Vitamins: Apples are known for being a good source of vitamins and minerals, and apple gummies are no exception. These gummies are often fortified with additional vitamins, such as vitamin C, to provide an extra nutritional boost. This means that you can enjoy a sweet treat while still getting essential nutrients that your body needs.
How to Enjoy Apple Gummies
1. On the Go: Apple gummies are the perfect snack to take with you while on the go. Whether you’re heading to work, running errands, or hitting the gym, these gummies are a convenient and portable option to satisfy your cravings. Simply toss a pack into your bag and enjoy them whenever you need a quick pick-me-up.
2. As a Dessert: If you’re looking for a healthier alternative to traditional desserts, consider using apple gummies as a topping for yogurt, ice cream, or oatmeal. Their sweet and tangy flavor can add a burst of taste to your favorite treats without the guilt of added sugars.
3. With Your Morning Coffee: Start your day off on the right foot by pairing your morning coffee with a few apple gummies. Their sweet flavor can complement the bitterness of coffee, creating a delicious contrast that will leave you feeling satisfied and energized.
Final Thoughts
Overall, apple gummies at Chemist Warehouse offer a healthy and delicious option for those looking to indulge in a sweet treat without sacrificing their health goals. With their natural ingredients, low calorie content, and added vitamins, these gummies are a guilt-free indulgence that you can enjoy any time of day. So why not pick up a pack of apple gummies today and treat yourself to a tasty snack that’s as good for your taste buds as it is for your body?
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Whether you’re a health-conscious consumer looking for a satisfying treat or just someone who loves the taste of fresh apples, apple gummies from Chemist Warehouse are sure to please. With their natural ingredients and nutritional benefits, these gummies are a great option for anyone looking to enjoy a sweet indulgence without the guilt. So why not give them a try and experience the delicious taste of apple gummies for yourself?