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Semaglutide has been making waves in the weight loss world as a promising treatment option for individuals struggling to lose excess weight. This groundbreaking drug, originally developed to treat type 2 diabetes, has been found to have significant effects on weight reduction when used in higher doses. In this article, we will explore how semaglutide works to aid in weight loss and why it is garnering attention as a potential game-changer in the fight against obesity.

Mechanism of Action

Semaglutide belongs to a class of medications known as GLP-1 receptor agonists. GLP-1 is a hormone produced in the gut that plays a crucial role in regulating blood sugar levels and appetite. By mimicking the effects of GLP-1, semaglutide helps to control blood sugar levels, decrease appetite, and promote feelings of fullness, leading to reduced calorie intake and ultimately, weight loss.





Additionally, semaglutide has been shown to slow down the rate at which food empties from the stomach, further contributing to a sense of fullness and satiety. This delayed gastric emptying can help individuals feel satisfied with smaller portions, making it easier to adhere to a reduced-calorie diet and achieve sustainable weight loss over time.

Furthermore, semaglutide may also have indirect effects on weight loss by improving insulin sensitivity and reducing inflammation in the body. These metabolic benefits not only support weight reduction but also have potential implications for the management of obesity-related health conditions such as insulin resistance, fatty liver disease, and cardiovascular risk factors.

Clinical Efficacy

Several clinical trials have demonstrated the efficacy of semaglutide for weight loss in individuals with obesity or overweight who have struggled to lose weight through lifestyle modifications alone. In one landmark study, participants who received the highest dose of semaglutide lost an average of 15% of their body weight over a 68-week period, significantly outperforming placebo-treated individuals.

Moreover, the weight loss achieved with semaglutide was shown to be sustained over the long term, with many participants maintaining substantial weight reduction even after discontinuing the medication. This suggests that semaglutide may not only help individuals lose weight but also assist in weight maintenance over time, making it a valuable tool in the management of obesity.

Additionally, semaglutide has been associated with improvements in various metabolic markers, such as blood pressure, cholesterol levels, and markers of inflammation, further underscoring its potential as a comprehensive treatment approach for individuals with obesity and metabolic health concerns.

Side Effects and Considerations

While semaglutide has shown remarkable promise as a weight loss medication, it is not without potential side effects and considerations. Common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation, which may occur especially during the initial phase of treatment and tend to improve over time as the body adjusts to the medication.

In rare cases, more serious side effects such as pancreatitis or thyroid tumors have been reported with the use of GLP-1 receptor agonists, although the overall risk remains low. It is important for individuals considering semaglutide for weight loss to weigh the potential benefits against the risks and to discuss any concerns with their healthcare provider before starting treatment.

Furthermore, semaglutide is currently approved for use in individuals with a body mass index (BMI) of 27 kg/m2 or higher with at least one weight-related health condition, or a BMI of 30 kg/m2 or higher. It is recommended to use semaglutide as part of a comprehensive weight loss plan that includes a reduced-calorie diet, increased physical activity, and behavior modification strategies to optimize results and support long-term success.

Conclusion

In conclusion, semaglutide offers a promising new option for individuals struggling with obesity and excess weight. By harnessing the power of GLP-1 receptor agonism, semaglutide helps to regulate appetite, promote feelings of fullness, and enhance weight loss efforts through multiple mechanisms of action. While some side effects and considerations exist, the potential benefits of semaglutide for weight management are significant and warrant further exploration in clinical practice.

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Breakfast hack: How to add protein to your breakfast scrambles and made them super fluffy at the same time. A breakfast high in protein will help you stay full for longer! Learn how to make the latest TikTok viral recipe step by step. Full recipe & macros at https://ketodietapp.com/Blog/lchf/fluffy-scrambled-eggs-with-cottage-cheese 🔹Ingredients: 3 large eggs 100 g cottage cheese (3.5 oz) 2 tbsp butter or olive oil (or 1 tbsp for lower fat) Salt & pepper to taste 1/8 to 1/4 tsp ground turmeric for an anti-inflammatory boost Fresh chives or herbs of choice 🔹Instructions are super simple. Just follow the recipe according to the video. Macros: 4.7 g net carbs (4.9 g total carbs), 30 g protein, 42 g fat, 518 kcal (calculated in our app https://ketodietapp.com/) Serving suggestions: - sliced avocado (fiber, potassium and monounsaturated fats) - salmon roe (Lyso-DHA, the best type of omega 3 fats) - smoked salmon (omega 3 fats, protein & potassium) 🔴 Our Keto Resources: Our KetoDiet App with tracking, recipes and custom diet plans (7 day free trial) ⟶ https://ketodietapp.com/start About Martina Slajerova ⟶ https://www.youtube.com/watch?v=vR2Hwz9x9ys Martina's 10 Keto Cookbooks: https://ketodietapp.com/books KetoDiet Support Group - join our community: https://www.facebook.com/groups/Ketodietplan Thousands of Low-Carb Recipes ⟶ https://ketodietapp.com/Blog/category/Recipes #shorts #keto #ketodiet #lowcarb

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Welcome to Day 11 of H40! If you've ever struggled with losing weight and keeping it off, today's lesson is for you. I'm sharing the really basic principle that makes fat loss possible - without crazy diets, hours of cardio, or feeling constantly hungry. Seriously, it’s not complicated once you understand this. Watch to see what I mean. Join our next sprint @ jointhesprint.org! #loseweight #losefat #health #healthy #fitness #fatloss #weightloss #fit #healthcommunity #fitnesscommunity #physicalfitness #burncalories #weightlossjourney #gainmuscle #burnfat #buringfat #fatburn

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What did a pilot study on How Not to Die’s Daily Dozen and How Not to Diet’s 21 Tweaks for weight loss find? I explain my traffic light system for ranking the relative healthfulness of Green Light vs. Yellow Light vs. Red Light foods in Dining by Traffic Light: Green Is for Go, Red Is for Stop (https://nutritionfacts.org/video/dining-by-traffic-light-green-is-for-go-red-is-for-stop/). The Daily Dozen was first introduced in How Not to Die (https://nutritionfacts.org/book/how-not-to-die/). Rather than being a meal plan or diet in itself, the Daily Dozen is to be used as a checklist to inspire you to eat more healthfully and design more balanced meals. Join us for 11 weeks of Daily Dozen support emails (https://nutritionfacts.org/daily-dozen/) to help you Do the Dozen with ease! Each week, we will send you an email with tips, tricks, facts, and tasty recipes to help you incorporate some of the healthiest of healthy foods into your daily routine. Check out How Not to Die (https://nutritionfacts.org/book/how-not-to-die/) and How Not to Diet (https://nutritionfacts.org/book/how-not-to-diet/) at your local library, available in print, e-book, and audio. (All proceeds I receive from the books are donated directly to charity.) New subscribers to our e-newsletter always receive a free gift. Get yours here: https://nutritionfacts.org/subscribe/. Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/video/daily-dozen-diet-put-to-the-test-for-weight-loss and someone on the NutritionFacts.org team will try to answer it. Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at https://nutritionfacts.org/video/daily-dozen-diet-put-to-the-test-for-weight-loss. You’ll also find a transcript and acknowledgements for the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 health topics. Thanks for watching. I hope you’ll join in the evidence-based nutrition revolution! -Michael Greger, MD FACLM Captions for this video are available in several languages; you can find yours in the video settings. View important information about our translated resources: https://nutritionfacts.org/translations-info/ https://NutritionFacts.org • Subscribe: https://nutritionfacts.org/subscribe • Donate: https://nutritionfacts.org/donate • Podcast : https://nutritionfacts.org/audio • Books: https://nutritionfacts.org/books • Shop: https://drgreger.org • Facebook: https://www.facebook.com/NutritionFacts.org • Twitter: https://twitter.com/nutrition_facts • Instagram: https://www.instagram.com/nutrition_facts_orgDirect Meds Glp1 Weight Loss I Ve Lost Weight But Gained Lot S Of Attention

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