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### **What Is a GLP-1 Medication?**
GLP-1 medications are drugs that mimic **glucagon-like peptide-1 (GLP-1)**, a hormone that helps regulate blood sugar levels and appetite. These medications are classified as **GLP-1 receptor agonists (GLP-1 RAs)** and are used primarily for **type 2 diabetes and weight management**.
### **What Are GLP-1 Medications Intended to Treat?**
GLP-1 medications are FDA-approved for:
1. **Type 2 Diabetes Mellitus (T2DM)** – They improve blood sugar control by enhancing insulin secretion and slowing digestion.
2. **Obesity & Weight Management** – Some GLP-1 drugs are approved for chronic weight management, as they reduce hunger and increase feelings of fullness.
🔹 **Examples of GLP-1 Medications:**
- **Semaglutide (Ozempic, Wegovy)** – Used for diabetes (Ozempic) and weight loss (Wegovy).
- **Liraglutide (Victoza, Saxenda)** – Victoza for diabetes, Saxenda for weight loss.
- **Dulaglutide (Trulicity)** – Primarily for diabetes.
- **Tirzepatide (Mounjaro, Zepbound)** – A dual GLP-1/GIP agonist, used for diabetes and weight loss.
### **Adverse Effects of GLP-1 Medications**
While these drugs are effective, they can cause several side effects:
✅ **Common Side Effects:**
- **Nausea**
- **Vomiting**
- **Diarrhea or constipation**
- **Reduced appetite**
⚠️ **Serious Adverse Effects:**
- **Gastroparesis (Delayed Stomach Emptying)** – Can cause severe nausea and bloating.
- **Pancreatitis** – Inflammation of the pancreas, which can be life-threatening.
- **Gallbladder Disease** – Increased risk of gallstones.
- **Thyroid Cancer Risk** – Some studies suggest a potential risk, especially in patients with a family history of **medullary thyroid cancer**.
- **Kidney Issues** – Can lead to dehydration and worsen kidney function in some patients.
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