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How To Lose Weight Fat Loss Factor By Dr Charles Livingston
Incidence of Obesity & Type 2 diabetes is increasing more than ever!
The current set of interventions are restricted to tracking blood sugar level using CGM, fad diets, high protein diets & pharmaceutical drugs.No wonder the therapeutic success is dismal!
Now India is experiencing another wave of synthetic compound approach- GLP-1 receptor Agonists with a hope to control glycemic control, trigger weight loss & improve cardiovascular health.
While at macro level this synthetic compound looks like a effective solution, if we dug deeper it may be starting point of metabolic disaster
What exactly is GLP-1?
GLP-1 is an incretin hormone naturally produced inside our body. Our gut microbiome could synthesise fibre, polyphenols & even N-oleoyl serinol in olive oil into GLP-1. This incretin hormone promotes satiety regulation, blood sugar control & even regulates heart health
If the body is not able to produce GLP-1, then it is a biochemistry problem & the body is not at ease. Since there has been no tech that could measure GLP-1 levels( we the only company in India that can measure & quantify this incretin hormone), it is assumed that people suffering from obesity or type 2 diabetes suffer from GLP-1 deficiency.
However no one actually measures specific inflammatory factors causing obesity. Is it really a GLP-1 deficiency? Or high P-cresol production? Low Butyrate Production? Elevated TMAO or high LPS?
Until you know the source code for obesity how can you even prescribe interventions to address the disease. GLP-1 receptor Agonists may work for some people who actually have GLP-1 deficiency. However, the effectiveness of this drug depends upon:
1.Functions of your microbiome. Certain microbes can synthesise these drugs into beneficial stuff that have positive correlation with glycemic reduction while some others if active & expressing virulence genes can interfere with synthesis of GLP-1 drugs
2.Certain microbes if active & expressing virulence genes can degrade GLP-1, making you gain weight or develop type 2 diabetes. In such scenario, these drugs cannot help
3.GLP-1 drugs also activates endothelial nitric oxide synthase which could potentiate nitric oxide signalling that could dilate blood vessels, regulate glucose uptake & have anti-obesity impact. However for this to function, this enzyme should be coupled with endothelial cells. If it is uncoupled due to systemic inflammation or oxidative stress, it cannot trigger production of nitric oxide & these GLP-1 drugs will not work
4. These drugs act as an artificial break on your satiety paddle & slow down movement along your digestive tract & would cause constipation, bloating & other digestive troubles.
5. Even for people this drug works, they need to take this continuously as withdrawal from these drugs would lead to weight gain
Citations
https://diabetesjournals.org/care/article/33/2/453/27096/GLP-1-Based-Therapy-for-Diabetes-What-You-Do-Not
https://pmc.ncbi.nlm.nih.gov/articles/PMC8793908/
https://pmc.ncbi.nlm.nih.gov/articles/PMC7021470/
https://pmc.ncbi.nlm.nih.gov/articles/PMC8833664/
https://dom-pubs.pericles-prod.literatumonline.com/doi/10.1111/dom.14725
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Discover the hottest topics in the world of GLP-1 weight loss medications! In this video, we dive deep into the latest updates on Mounjaro, Zepbound, Ozempic, and Wegovy, discussing hot topics about these groundbreaking weight loss treatments. Whether you're just starting your weight loss journey or are already using GLP-1 medications, this video is packed with valuable insights for men and women looking to achieve their health goalsI. f you’re a woman or man on a weight loss journey, especially those over 40 or 50, or using medications like Mounjaro, Zpebound, Ozempic, or Wegovy this video is for you. Learn how GLP-1 receptor agonists are transforming weight loss, controlling appetite, and improving metabolic health. #mounjaro #zepbound #glp1medication Hot Topics: -Natural Weight Loss Vs GLP1 Weight Loss -Taking a GLP1 The Easy Way Out -Big Back Behavior -Eli Lilly Weight Loss Pill Don’t forget to like, comment, and subscribe for more weight loss tips, updates, and inspiration. Join the conversation and stay informed about the latest trends in weight management! Subscribe to my channel: youtube.com/@DownsizingDiva?sub_confirmation=1 Join the Membership: https://www.youtube.com/channel/UCO6yCfVnuMPQaZXRrHKGBKw/join Email: downsizingdiva8@gmail.com @ManOnTheMounjaro Video: https://youtu.be/ZsgHHZ39Xa8?si=sdoe_FoWeHt3UXKW Amazon Affiliate Links to help you on your Weight Loss Journey: LifePro 3D Vibration Plate Exercise Machine: https://a.co/d/7HQmLH8 Niceday Steppers for Exercise: https://a.co/d/5s8SCGa nbpure MagO7 - Natural Colon Cleanse & Detox: https://a.co/d/3U3mA4L Pure Encapsulations Magnesium (Glycinate): https://a.co/d/3HJsGZR TULA Skin Care 24-7 Hydrating Day & Night Cream: https://a.co/d/5wIDtio TULA Skin Care Clarifying Tonic Alcohol-Free Daily Toner: https://a.co/d/c8LQqSd *Get a free LMNT Sample Pack using my referral link with your first purchase so you can try out more flavors. Thank you & Stay Hydrated! LMNT Electrolyte Link: https://elementallabs.refr.cc/default/u/downsizingdivaGruns Gummy Vitamins Link: https://www.gruns.co/pages/vip?snowball=downsizingdiva38294If you would like to donate to my channel: Cash App: $downsizingdiva8 Want to create live streams like this? Check out StreamYard: https://streamyard.com/pal/d/5125869032308736
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