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Semaglutide is a novel weight loss medication that has been garnering attention in recent years for its effectiveness in helping individuals shed excess pounds. This drug, originally approved for the treatment of type 2 diabetes, has shown promising results in clinical trials for promoting weight loss in overweight and obese individuals. But how exactly does semaglutide work to facilitate weight loss?
1. Appetite Suppression
One of the key mechanisms through which semaglutide aids in weight loss is by suppressing appetite. This medication works by mimicking the effects of a hormone called glucagon-like peptide-1 (GLP-1), which is naturally produced in the body. GLP-1 helps regulate appetite and food intake by signaling to the brain that the stomach is full. By increasing the levels of GLP-1 in the body, semaglutide can help individuals feel more satisfied with smaller meals, leading to reduced calorie intake and eventual weight loss.
Furthermore, semaglutide also slows down the rate at which the stomach empties, which can help individuals feel full for longer periods after eating. This can prevent overeating and snacking between meals, further aiding in weight loss efforts.
In clinical trials, individuals taking semaglutide reported feeling less hungry and experiencing fewer cravings for high-calorie foods. This decreased appetite and increased satiety can make it easier for individuals to adhere to a calorie-restricted diet and make healthier food choices, ultimately leading to successful weight loss.
2. Improved Insulin Sensitivity
In addition to its appetite-suppressing effects, semaglutide also helps improve insulin sensitivity in individuals with type 2 diabetes. Insulin resistance is a common characteristic of obesity and can make it challenging for individuals to lose weight. By enhancing insulin sensitivity, semaglutide can help the body more effectively use glucose for energy, which can aid in weight loss.
Improved insulin sensitivity can also help regulate blood sugar levels and reduce the risk of developing type 2 diabetes or other obesity-related health conditions. By addressing underlying metabolic issues, semaglutide can support long-term weight management and overall health.
Studies have shown that individuals taking semaglutide experience significant improvements in their insulin sensitivity, even in the absence of weight loss. This suggests that the medication can help address metabolic dysfunction and promote overall health and well-being in addition to aiding in weight loss efforts.
3. Increased Energy Expenditure
Another way that semaglutide helps with weight loss is by increasing energy expenditure in the body. This medication has been shown to boost metabolism, allowing individuals to burn more calories at rest and during physical activity. By enhancing energy expenditure, semaglutide can help individuals create a calorie deficit, which is essential for weight loss.
Studies have demonstrated that individuals taking semaglutide experience a greater increase in resting metabolic rate compared to those taking a placebo. This means that individuals on semaglutide burn more calories while at rest, making it easier for them to lose weight and maintain their results over time.
By combining appetite suppression with improved energy expenditure, semaglutide offers a comprehensive approach to weight loss that addresses both sides of the energy balance equation. This dual-action mechanism can make it easier for individuals to achieve their weight loss goals and sustain their results in the long term.
4. Maintenance of Weight Loss
One of the challenges of weight loss is maintaining the results over time. Many individuals struggle to keep the weight off once they reach their goal, often experiencing weight regain within a few months. Semaglutide has shown promise in helping individuals maintain weight loss and prevent regain through its unique mechanisms of action.
By regulating appetite, improving insulin sensitivity, and increasing energy expenditure, semaglutide can help individuals develop healthier eating habits, stabilize blood sugar levels, and continue burning calories efficiently even after weight loss is achieved. This can make it easier for individuals to maintain their weight loss and prevent the yo-yo dieting cycle that is common with other weight loss methods.
Clinical trials have demonstrated that individuals taking semaglutide not only lose weight more effectively than those on a placebo but also have a lower risk of regaining the weight in the months following treatment discontinuation. This suggests that semaglutide may offer a sustainable solution for long-term weight management and overall health improvement.
5. Potential Side Effects
While semaglutide has shown significant benefits for weight loss, it is essential to consider the potential side effects associated with this medication. Common side effects may include nausea, vomiting, diarrhea, and constipation, particularly when starting treatment. These gastrointestinal symptoms typically subside over time as the body adjusts to the medication.
Less common but more serious side effects of semaglutide may include pancreatitis, gallbladder problems, and kidney damage. It is important for individuals considering semaglutide for weight loss to discuss the potential risks and benefits with their healthcare provider and closely monitor any changes in their health while taking the medication.
Additionally, semaglutide is not suitable for everyone, and individuals with a history of pancreatitis, thyroid cancer, or certain gastrointestinal conditions may be advised against using this medication. It is crucial to undergo a thorough medical evaluation and discuss all treatment options with a healthcare provider before starting semaglutide or any other weight loss medication.
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Head to Sugarmds.com to join our newsletter! Discover exclusive secrets on reversing diabetes and unique care methods you won't find anywhere else. Want to know about metformin dosage and learn about metformin side effects for diabetes or PCOS? Metformin has multiple dosages and how to take metformin makes a big difference in how many side effects you get from metformin? Dr. Ergin(SUGARMD) talks about everything you need to know about metformin in this video. In addition to the above Dr. Ergin discusses why metformin was recalled, is metformin good or bad for your heart, and whether it is associated with cancer or not.
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Who is Dr. Ergin? Dr. Ahmet Ergin is an endocrinologist with a particular interest and passion for diabetes care. Dr. Ergin earned his medical degree with honors at Marmara University School of Medicine in Istanbul, Turkey. Then, he completed his internal medicine residency and endocrinology fellowship at Cleveland Clinic in Cleveland, Ohio. He is a board-certified physician in Internal Medicine and Endocrinology, diabetes, and metabolism. He is also a certified diabetes education specialist.
Disclaimer: Any information on diseases and treatments available at this channel is intended for general guidance only and must never be considered a substitute for the advice provided by your doctor or other qualified healthcare professionals. Always seek the advice of your physician or other qualified healthcare professionals with questions you may have regarding your medical condition.
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Ahmet Ergin, MD (doctor en Medicina), FACE, educador certificado en diabetes (CDCES), Endocrinรณlogo ECNU, Educador de Diabetes www.SugarMDs.com Ahmet Ergin, MD (doctor en Medicina), es un mรฉdico especialista en endocrinologรญa, diabetes y metabolismo.
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Semaglutide is a medication that has gained popularity in recent years for its potential to aid in weight loss. Originally approved to treat type 2 diabetes, semaglutide has shown promise in helping individuals lose weight as well. However, many people are unsure of how long they can safely be on semaglutide for weight loss before potential side effects or diminishing returns occur. In this article, we will explore the safety and effectiveness of semaglutide for weight loss and discuss the duration for which it can be used.
Understanding Semaglutide for Weight Loss
Semaglutide is a medication that belongs to a class of drugs known as GLP-1 receptor agonists. These drugs work by mimicking the effects of glucagon-like peptide-1 (GLP-1), a hormone that helps regulate blood sugar levels and appetite. By activating GLP-1 receptors in the brain, semaglutide can help reduce hunger and increase feelings of fullness, leading to decreased calorie intake and, ultimately, weight loss.
Studies have shown that semaglutide can be effective in helping individuals lose weight. In fact, in clinical trials, participants who took semaglutide for weight loss experienced significant reductions in body weight compared to those who took a placebo. Some individuals even lost more than 15% of their initial body weight while taking semaglutide.
One of the key benefits of semaglutide for weight loss is that it is generally well-tolerated by most people. Common side effects may include nausea, vomiting, diarrhea, and constipation, but these are usually mild and tend to improve over time. However, as with any medication, there may be risks associated with long-term use, so it is important to discuss the duration of treatment with your healthcare provider.
Duration of Semaglutide Treatment
The duration for which semaglutide can be safely used for weight loss will vary depending on the individual. In general, most healthcare providers recommend using semaglutide for weight loss for a minimum of 12-14 weeks to see significant results. After this initial period, your healthcare provider may recommend continuing treatment if you are still benefiting from semaglutide and experiencing weight loss.
Some individuals may be able to safely use semaglutide for weight loss for longer periods of time, up to a year or more. However, it is essential to regularly monitor your progress and discuss any concerns or side effects with your healthcare provider. They can help determine the appropriate duration of treatment based on your individual needs and health status.
It is important to note that semaglutide is not a quick fix for weight loss and should be used in conjunction with a healthy diet and regular exercise. While semaglutide can help support weight loss efforts, it is not a replacement for lifestyle changes and should be part of a comprehensive weight management plan.
Final Thoughts on Semaglutide for Weight Loss
In conclusion, semaglutide can be a valuable tool for individuals looking to lose weight and improve their overall health. While the duration for which semaglutide can be used for weight loss may vary, it is important to work closely with your healthcare provider to determine the best course of treatment for you. By incorporating semaglutide into a comprehensive weight management plan that includes healthy eating and regular exercise, you can maximize the benefits of this medication and achieve long-term weight loss success.
If you are considering using semaglutide for weight loss, be sure to consult with your healthcare provider to discuss the potential risks and benefits of treatment. They can help determine if semaglutide is the right option for you and provide guidance on how long you can safely use it for weight loss.
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A plant-based diet may not only be the safest treatment for multiple sclerosis, it may also be the most effective.
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I touched on this in my live 2013 year-in-review lecture More Than an Apple a Day (http://nutritionfacts.org/video/more-than-an-apple-a-day-preventing-our-most-common-diseases), but I'm excited to be able to take a deeper dive into this extraordinary story.
Those interested in supporting Dr. McDougall's landmark study (headed by Dr. Dennis Bourdette, M.D. and under the supervision of Dr. Vijayshree Yadav) can donate to his nonprofit McDougall Research & Education Foundation (http://www.drmcdougall.com/about/foundation/) (you can also donate to NutritionFacts.org to help keep us bringing you similarly underreported yet life-saving science by clicking on the Donate, https://nutritionfacts.org/donate/, button above).
Another reason Dr. Swank's work hasn't been embraced may be The Tomato Effect (http://nutritionfacts.org/video/the-tomato-effect/).
Other videos on the role diet may play in neurological disorders include:
โข Preventing Parkinson's Disease With Diet (http://nutritionfacts.org/video/preventing-parkinsons-disease-with-diet/)
โข Treating Parkinson's Disease With Diet (http://nutritionfacts.org/video/treating-parkinsons-disease-with-diet/)
โข Pork Tapeworms on the Brain (http://nutritionfacts.org/video/pork-tapeworms-on-the-brain/)
โข Nerves of Mercury (http://nutritionfacts.org/video/nerves-of-mercury/)
What's in sausage and eggs that may cause so much inflammation? See my video series on endotoxins described in my blog How Does Meat Cause Inflammation? (http://nutritionfacts.org/2012/09/20/why-meat-causes-inflammation/.)
Where is saturated fat found? See Trans Fat, Saturated Fat, and Cholesterol: Tolerable Upper Intake of Zero (http://nutritionfacts.org/video/trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero/).
Those unfamiliar with Pritikin can watch a short introduction in Engineering a Cure (http://nutritionfacts.org/video/engineering-a-cure/), and Ornish and Esselstyn's great work is profiled in videos like Our Number One Killer Can Be Stopped (http://nutritionfacts.org/video/our-number-one-killer-can-be-stopped/) and China Study on Sudden Cardiac Death (http://nutritionfacts.org/video/china-study-on-sudden-cardiac-death/).
Have a question for Dr. Greger about this video? Leave it in the comment section at http://nutritionfacts.org/video/treating-multiple-sclerosis-with-the-swank-ms-diet/ and he'll try to answer it!
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Dr. Casey Means is a leading metabolic health expert and doctor from Stanford Medical School, NIH researcher, co-founder of health tech company Levels, and author of New York Times best-selling book Good Energy.
She provides a science-based, nuanced perspective on the hot topics of Ozempic, weight loss, and the underlying metabolic crisis in America. Casey and Liz discuss the distinction between obesity and metabolic health, the influence of modern lifestyles on metabolic dysfunction, and the holistic approaches needed to improve metabolic health without relying solely on medications like Ozempic or Wegovy. The conversation also explores practical strategies to enhance mitochondrial function, such as dietary adjustments, movement vs. exercise, and reducing exposure to toxins. If you're looking to understand the science behind metabolic health and gain actionable insights to improve your well-being, this episode is a must-listen.
LISTEN / SUBSCRIBE TO THE PODCAST
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00:00 Intro
02:24 The Obesity and Metabolic Health Debate
04:57 Understanding Different Types of Fat: Subcutaneous, Visceral, and Intracellular
06:36 Ozempic's Impact on Metabolic Health
07:56 Mitochondria and Metabolic Health
08:32 The Eight Pillars Affecting Mitochondria
12:00 Ozempic: Mechanisms and Physical Effects
26:24 Natural Ways to Boost GLP-1 and Inhibit DPP-4
30:22 The Food Industry and Cravings
37:42 The Consequences of Obesity and the Healthcare System
38:50 Personal Responsibility vs. Systemic Forces
39:43 The Impact of Policy on Health
40:53 Understanding Metabolic Health
45:09 Tracking Biomarkers for Better Health
47:34 Addressing Hidden Health Issues
58:11 The Importance of Movement vs Exercise
59:57 The Dangers of Ultra-Processed Foods
64:21 The Root Cause of Health Issues
If youโre new here, Iโm Liz Moody! Iโm a longtime journalist, thought leader, and best-selling author. I host The Liz Moody Podcast where every week, weโre sharing real science, real stories, and realistic tools that ACTUALLY level up every part of your life. If you want to know more, visit my website or check me out on The TODAY Show with Hoda Kotb and Jenna Bush Hager:
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The Liz Moody Podcast Episode 250.
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