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Semaglutide is a medication that has recently gained popularity for its potential to aid in weight loss. This drug is a glucagon-like peptide-1 (GLP-1) receptor agonist, which means it works by increasing feelings of fullness, slowing gastric emptying, and reducing appetite. Semaglutide was initially approved for the treatment of type 2 diabetes, but studies have shown that it can also be effective in promoting weight loss in individuals who are overweight or obese. The weight loss results with semaglutide have been impressive, with some clinical trials showing that patients can lose up to 15% of their body weight.

Semaglutide Mechanism of Action

Semaglutide works by mimicking the effects of the natural hormone GLP-1, which is produced in the intestines in response to food intake. GLP-1 helps to regulate blood sugar levels and promotes weight loss by signaling to the brain that you are full and reducing hunger. By activating the GLP-1 receptor, semaglutide can help to control appetite and food intake, leading to weight loss.

Semaglutide also slows down the emptying of the stomach, which can help you feel full for longer periods of time. This can reduce the urge to eat and help you consume fewer calories throughout the day. Additionally, semaglutide can improve insulin sensitivity and reduce glucose production in the liver, leading to better blood sugar control.





Another way that semaglutide promotes weight loss is by increasing the body’s energy expenditure, or the number of calories burned at rest. This can help to boost metabolism and further aid in weight loss efforts. Overall, the multiple mechanisms of action of semaglutide make it a powerful tool for achieving and maintaining weight loss.

Semaglutide Weight Loss Cost

As with any medication, the cost of semaglutide can vary depending on several factors, including your insurance coverage, pharmacy discounts, and the dosage prescribed by your healthcare provider. Semaglutide is available in both injection pens and prefilled syringes, with different strengths and dosing regimens. The price per dose can range from around $900 to $1,200, but some insurance plans may cover a portion of the cost.

If you are concerned about the cost of semaglutide for weight loss, there are ways to save money and make treatment more affordable. Some pharmaceutical companies offer patient assistance programs or copay cards that can help reduce the out-of-pocket expenses for semaglutide. Additionally, you may be able to find discounts or coupons from the manufacturer or through online pharmacies.

Before starting semaglutide for weight loss, it is important to discuss the cost with your healthcare provider and explore all available options for saving money on the medication. Your doctor may be able to provide guidance on how to navigate insurance coverage and find resources to help make semaglutide more affordable for you.

Tips for Saving on Semaglutide Weight Loss

One way to save on the cost of semaglutide for weight loss is to use a pharmacy discount card or coupon. These discounts can help lower the price of the medication and make it more affordable for patients. Some websites offer free savings cards that can be used at most pharmacies to reduce the cost of semaglutide.

Another tip for saving on semaglutide is to check with your insurance provider to see if the medication is covered under your plan. Some insurance companies may cover a portion of the cost of semaglutide, especially if it is prescribed for weight loss purposes. It is important to verify coverage and understand any copays or out-of-pocket expenses associated with the medication.

You can also ask your healthcare provider about any patient assistance programs or manufacturer discounts that may be available for semaglutide. These programs can help reduce the cost of the medication and make treatment more affordable for those who qualify. Your doctor may have information on how to apply for these programs and access savings on semaglutide.

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Conclusion

Semaglutide is a promising medication for weight loss that has shown significant results in clinical trials. However, the cost of semaglutide can be a concern for some patients, especially if insurance coverage is limited. By exploring different ways to save on semaglutide, such as utilizing pharmacy discounts, patient assistance programs, and insurance coverage, you can make treatment more affordable and accessible. Discussing the cost of semaglutide with your healthcare provider and researching available resources can help you navigate the financial aspects of starting treatment and achieve your weight loss goals.

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GLP-1s are so powerful if you’re using the right dose, you should NEVER have to increase it. If it doesn't work, it’s not the drug it’s your diet, training, or hormones that should be optimized. Comment "CHEAT SHEET" for a free peptide guide!

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This is the story of how GLP-1 receptor agonist drugs like semaglutide and tirzepatide were developed. Support my work on Nebula: https://go.nebula.tv/patrickkelly ☠️NONE OF THE INFORMATION IN THIS VIDEO SHOULD BE USED AS MEDICAL ADVICE OR OPINION. IT IS FOR GENERAL EDUCATION AND ENTERTAINMENT☠️ 🎬C R E D I T S🎬 Written, performed, and edited by Patrick Kelly Select imagery/video supplied by Getty Images Thank you to Dr. Svetlana Mojsov and Rockefeller Institute for the use of Dr. Mojsov's portrait 🔗 L I N K S 🔗 📱Instagram: https://www.instagram.com/patkellyteaches/ 💰Patreon: https://www.patreon.com/corporis 🔬Old channel: www.youtube.com/corporis/ 📚Book recommendations: www.patkellyteaches.com/books 🔑 P A T R O N S 🔑 Oxytocin Tier: Mike W | Paul R | Daphnanne P | Oliver W | Tal Globus | Paul Belmes Growth Hormone Tier: Carey & Jack P | Brendan P | Brandon K | Kristofer R | Joe B | Mindi F | Michael G | Brian B | Eileen H | Waffles the Dog | Brian T | Brian H | Michael R | Karen S | Sarah B | Robin B | Jacob S | Hyeon-Seo | Paul! | Lucy Fur | Huynhy | Jim C | elnombre91 | Alcedo | Josef K | Dab B | Robert M | Jiggs | TierZoo | Seth G | Jane G | Jack M | Matthew B | Michelle J | Helena SB | Eric L | Ryne J | Kilian | Dean M | Cody S | Michelle L | Joseph G | Aryan R | Vic K | Becca | Jesse B | Stella | Marc M | Roxanna A | Doyle V | Maria A | Karen S | Jon A | Brian | Blake | Caitlin E | David W | DrCredibleHulk | Eugene F | Anthony DiF | Charlie C | Reniece J | chris | Rachel J | ZoeMarie | Katie B-S | Broderic D | CJ 📜 S O U R C E S 📜 An annotated version of the script can be found on Patreon: https://www.patreon.com/posts/glp-1-video-133601476?utm_medium=clipboard_copy&utm_source=copyLink&utm_campaign=postshare_creator&utm_content=join_link Novo Nordisk (2023) by Kurt Jacobsen The discovery and development of GLP-1 based drugs that have revolutionized the treatment of obesity (2024) https://www.pnas.org/doi/10.1073/pnas.2415550121 Glucagon as the First Incretin: Objects (in the Rearview Mirror) Are Closer Than They Appear (2023) https://diabetesjournals.org/diabetes/article/72/12/1739/153849/Glucagon-as-the-First-Incretin-Objects-in-the The development of Byetta (exenatide) (2012) https://www.sciencedirect.com/science/article/pii/S0041010110004472 The time has come for incretins, a long time coming (2010) https://link.springer.com/content/pdf/10.1007/s00109-009-0586-5.pdf Dual GIP–GLP1-Receptor Agonists In The Treatment Of Type 2 Diabetes: A Short Review On Emerging Data And Therapeutic Potential (2019) https://www.dovepress.com/article/download/48870 Type 2 Diabetes https://diabetesatlas.org/media/uploads/sites/3/2025/02/IDF-Atlas-2nd-Edition.pdf https://diabetes.org/about-diabetes/type-1 https://www.ncbi.nlm.nih.gov/books/NBK507839/ https://www-sciencedirect-com.harker.idm.oclc.org/science/article/pii/S0169409X02000935?via%3Dihub FDA Shortages: https://www.fda.gov/media/185526/download?attachment 💻 C O N T A C T 💻 patkellyteaches [at] gmail.com ⌛T I M E S T A M P S ⌛ 0:00 intro 0:52 GLP-1 as a hormone 9:50 GLP-1 as a diabetes drug 13:00 exenatide 16:21 liraglutide 19:20 GLP-1 as an obesity drug 24:25 dulaglutide 25:23 semaglutide 28:40 tirzepatide 30:45 Compounding pharmacies 33:26 Conclusion #historyofmedicine #medicalhistory

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