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GLP-1 (Glucagon-Like Peptide-1) is a type of incretin hormone that plays a significant role in glucose metabolism and appetite regulation. GLP-1 compounds, including medications like liraglutide (Saxenda, Victoza) and semaglutide (Ozempic, Wegovy), are used primarily in the treatment of type 2 diabetes and obesity.
Key Functions:
Blood Sugar Control: GLP-1 enhances insulin secretion in response to meals, helping lower blood sugar levels.
Appetite Regulation: These compounds can help reduce appetite and promote weight loss by affecting the brain's appetite centers.
Cardiovascular Benefits: Some GLP-1 agonists have been shown to have positive effects on heart health.
Mechanism of Action:
GLP-1 compounds mimic the action of the natural GLP-1 hormone, leading to increased insulin secretion, decreased glucagon secretion, and slowed gastric emptying.
Uses:
Weight Management: They are effective for individuals with obesity or those seeking weight loss.
Diabetes Management: Prescribed for patients with type 2 diabetes who seek improved glycemic control.
Side Effects:
Common side effects may include nausea, vomiting, diarrhea, and risk of pancreatitis.
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Eli Lilly & Co. will begin studies to see if its blockbuster weight-loss medicines can also be used to treat addictive behaviors like alcohol abuse, smoking and drug addiction, Chief Executive Officer Dave Ricks said. These medicines can be useful for other things we don’t think about connected to weight,” Ricks said during an interview with David Rubenstein at a meeting of the Economics Club in Washington, DC.
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1 teaspoon black pepper
1 teaspoon garlic powder (optional)
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