Ozempic Underworld The Black Market Of Weight Loss Drugs
Several weeks ago, we briefly talked about oral semaglutide (Rybelsus) when we addressed the current concern surrounding the Wegovy shortage. And although it's currently not approved for weight loss, there is a lot buzz surrounding the hope that it soon will be, and its clinical results for weight loss have been promising. But remember, you can't always believe what you read unless there's science to back it up.
Today I'd like to talk about oral semaglutide, the current clinical studies surrounding its efficacy for weight loss, and things to consider with oral weight loss medications.
What is Rybelsus?
We've talked about Rybelsus before. It's the oral version of semaglutide. It contains the same active ingredient as Ozempic and Wegovy. Because all three of these medications have the same active ingredient, they work the same way in your body. After you eat a meal, semaglutide helps to lower your blood sugar by mimicking a gut hormone called glucagon-like peptide-1 (GLP-1). This causes your pancreas to release insulin and blocks your liver from releasing sugar. It also slows down how quickly food leaves your stomach. This makes you feel full longer and suppress your appetite. All of these things together lead to weight loss.
The most obvious difference between the medications is how they're taken. Wegovy and Ozempic are once weekly injections, while Rybelsus is a pill you have to take by mouth every day.
Like Ozempic, Rybelsus is not approved for weight loss management even though loss of appetite may occur. Currently, Rybelsus should only be used to treat type 2 diabetes.
It's also important to remember that Rybelsus comes in 3mg, 7mg, and 14mg strengths. Only patients taking the Ozempic 0.5mg dose for type 2 diabetes can switch to Rybelsus.
And, like Wegovy and Ozempic, Rybelsis can also cause similar stomach-related side effects like nausea, vomiting, diarrhea, and constipation.
What do the clinical studies show?
A 68-week study with almost 670 adult participants reported an average weight loss of nearly 15% taking oral semaglutide 50mg daily. The placebo group lost an average of 2.4% of their body weight. This is similar to the results from the largest Wegovy trial (2,000 adult participants), which showed about 15% average weight loss within the same time period.
Things to consider
Higher doses: The Rybelsus doses studied for weight loss were 50 mg daily. Currently, Rybelsus comes in 3mg, 7mg, and 14mg strengths. The manufacturer plans to request FDA approval for the 50mg dose if approved for weight loss.
Convenience: The tablets must also be taken first thing in the morning with no more than 4 ounces of water. You must wait 30 minutes before eating, drinking, or taking other medications to absorb the Rybelsus fully. Initially, injections may seem scary, but with some practice, giving yourself a shot under the skin can be painless. Often the needles used for subcutaneous injections are as thin as two strands of hair. Would you rather give yourself a weekly injection or remember to take a daily pill?
Heart benefits: Rybelsus is great for people with type 2 diabetes who don't want to give themselves injections. However, unlike Ozempic and Wegovy, Rybelsus doesn't have the same heart-related benefits (lower risk of heart attack and stroke). In fact, studies have shown to lower the risk of death due to heart problems in certain people by 26%.
Medication Interactions: Rybelsus has been shown to lower the absorption of levothyroxine (a thyroid medication) by 33%. Make sure to let your healthcare provider know your full list of medications so they can check for potential drug interactions while taking Rybelsus.
Cost: The average cash price (without prescription insurance) of Rybelsus is $1,100 for 30 tablets (3mg, 7mg, or 14mg tablets). This is lower than the average cash price of Wegovy which is about $1,500 for 4 prefilled pens. Price tags on these weight loss medications don't come cheap and, without the help of insurance, are out of reach for many. I don't anticipate the price for 50 mg Rybelsus tablets to be much better. It will likely have a similar cash price of around $1,000-1,1500 for 30 tablets.
Thanks again for listening to The Peptide Podcast, we love having you as part of our community. You can find out more information about semaglutide on our previous podcasts.
If you love this podcast, please share it with your friends and family on social media, and have a happy, healthy week!
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Little Blue Gummies CBD for ED: Tiny Steps Towards a Healthier Weight
Introduction
As men age, many may experience erectile dysfunction (ED), a common condition that can have a significant impact on their quality of life. While there are various treatments available for ED, some are turning to alternative remedies such as CBD gummies to help manage their symptoms. In recent years, CBD has gained popularity for its potential health benefits, including its ability to reduce inflammation, anxiety, and pain.
One particular product that has caught the attention of men looking to improve their sexual health is Little Blue Gummies CBD. These tiny blue gummies contain CBD, a non-psychoactive compound found in cannabis that has been shown to have various health benefits. By incorporating these gummies into their daily routine, men with ED may be able to take small steps towards a healthier weight and improved sexual function.
In this article, we will explore the potential benefits of Little Blue Gummies CBD for ED and how they may help men on their journey towards a healthier weight. We will discuss the science behind CBD, the role it plays in managing ED, and how these gummies can be incorporated into a healthy lifestyle. By taking these tiny steps, men may be able to improve their overall well-being and sexual health.
Understanding CBD and ED
Cannabidiol, or CBD, is a natural compound found in cannabis plants that has been shown to have various health benefits. Unlike tetrahydrocannabinol (THC), another compound found in cannabis that produces a “high,” CBD is non-psychoactive. This makes it a popular choice for those seeking the potential therapeutic effects of cannabis without the intoxicating side effects.
Research has shown that CBD may help improve symptoms of ED by reducing anxiety, inflammation, and pain. Anxiety is a common cause of ED, as stress can interfere with the brain’s ability to send signals to the penis to initiate an erection. By reducing anxiety levels, CBD may help men relax and improve their sexual performance.
In addition, CBD has anti-inflammatory properties that may help improve blood flow to the penis. Erectile dysfunction is often caused by a lack of blood flow to the penis, making it difficult to achieve or maintain an erection. By reducing inflammation in the body, CBD may help improve circulation and support better sexual function.
Benefits of Little Blue Gummies CBD for ED
Little Blue Gummies CBD offer a convenient and discreet way to incorporate CBD into your daily routine. These tiny gummies are easy to take on the go and provide a precise dose of CBD with each serving. By incorporating Little Blue Gummies into your daily regimen, you may experience the potential benefits of CBD for managing ED and improving your sexual health.
One of the key benefits of Little Blue Gummies CBD is their ability to help reduce anxiety and stress, which are common contributors to ED. By taking these gummies regularly, you may notice a reduction in anxiety levels and an improvement in your overall well-being. This can lead to better sexual performance and a more satisfying sex life.
In addition, Little Blue Gummies CBD may help improve blood flow to the penis, making it easier to achieve and maintain an erection. By supporting circulation and reducing inflammation, these gummies may help support better sexual function and promote overall sexual health. Incorporating Little Blue Gummies into your routine may be a small but important step towards a healthier weight and improved sexual function.
Incorporating Little Blue Gummies CBD into Your Routine
When incorporating Little Blue Gummies CBD into your routine, it’s important to start with a low dose and gradually increase as needed. Begin by taking one gummy per day and monitor how your body responds. If you find that you need more CBD to manage your symptoms, you can gradually increase your dose to two or three gummies per day.
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It’s also important to note that CBD gummies may take some time to take effect, as they need to be digested before the CBD can be absorbed into the bloodstream. Give yourself some time to adjust to the gummies and be patient as you wait for the potential benefits to kick in. With regular use, you may begin to notice improvements in your sexual health and overall well-being.
In addition to taking Little Blue Gummies CBD, it’s important to maintain a healthy lifestyle to support your sexual health goals. Eat a balanced diet, exercise regularly, and get plenty of rest to help support your body’s natural ability to function optimally. By taking these small steps towards a healthier lifestyle, you may be able to improve your sexual function and overall well-being.
Summary and FAQs
Overall, Little Blue Gummies CBD may offer potential benefits for men with ED who are looking to improve their sexual health and achieve a healthier weight. By incorporating these tiny gummies into their daily routine, men may be able to take small steps towards better sexual function and overall well-being.
Here are some frequently asked questions about Little Blue Gummies CBD:
1. Are Little Blue Gummies CBD legal?
Yes, Little Blue Gummies CBD are legal in the United States as long as they contain less than 0.3% THC.
2. Can CBD gummies help with ED?
Research suggests that CBD may help manage symptoms of ED by reducing anxiety, inflammation, and pain.
3. How should I take Little Blue Gummies CBD?
Start with a low dose and gradually increase as needed. Monitor how your body responds and adjust your dose accordingly.
4. Are there any side effects of taking CBD gummies?
While CBD is generally well-tolerated, some people may experience side effects such as drowsiness, dry mouth, or changes in appetite.
5. Where can I purchase Little Blue Gummies CBD?
You can purchase Little Blue Gummies CBD online or at select retailers that carry CBD products.
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