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Some people follow a ketogenic diet seeking to lose weight, feel more energised, or gain control over their eating habits. Others may turn to this diet in an effort to treat their epilepsy, bipolar disorder, or diabetes. Regardless of their reasoning for adopting this eating pattern, a key question remains: can high LDL cholesterol levels on a ketogenic diet be safe? In Episode #311, I’m joined by Dr William Cromwell, MD and Dave Feldman to explore this question. :point_down: Visit The Proof website for the full show notes and supporting studies. :point_down: https://theproof.com/podcast/ Dr William Cromwell is a lipidologist with over 35 years of clinical practice experience. Since 1990, Dr Cromwell’s practice has specialised in managing lipid and lipoprotein disorders. He has authored over two dozen peer-reviewed papers and book chapters on evaluating and managing lipoprotein disorders and lipoprotein analytics. Dave Feldman is a software and platform engineer, an entrepreneur, and founder of the Citizen Science Foundation. His life took a radical turn on seeing his cholesterol skyrocket after adopting a ketogenic diet, leading him to research lipidology. Through a series of self-experiments and partnering with formal researchers, he has since published the "Lipid Energy Model" which may explain this phenomenon. Connect with Dr William Cromwell: - Twitter/X (personal): /lipoprotein - Twitter/X (Precision Health Reports): / precisehlthrpt - LinkedIn (personal): /wcromwellmd - LinkedIn (Precision Health Reports): / precisionhealthreports - Facebook: / precisionhealthreports - Instagram: / precisehlthrpt - Website (personal): https://www.mylipid.com/ - Website (Precision Health Reports): https://precisionhealthreports.com/ Connect with Dave Feldman: - Twitter/X: / realdavefeldman - YouTube: / @realdavefeldman - Instagram: / realdavefeldman - Citizen Science Foundation: https://citizensciencefoundation.org/ - Own Your Labs: https://ownyourlabs.com/ - Cholesterol Code: https://cholesterolcode.com/ We covered: 00:00 Intro 01:54 Dr. William Cromwell: Background as a Lipidologist and LDL Research 05:34 Dave Feldman's Ketogenic Diet and Elevated LDL Experience 12:30 Unpacking the Lipid Hypothesis and Cardiovascular Risk 20:40 The history and evolution of the lipid hypothesis 23:39 The role of apoB lipoproteins in atherosclerosis 31:59 Factors beyond apoB involved in atherosclerosis and mortality risk 41:43 The complexity of interpreting mortality data in the context of apoB 44:00 Macrophages and the process of atherosclerosis 52:57 Beyond ApoB: Metabolic Vulnerability, Inflammation and Mortality Risk 1:10:35 Transcytosis: A New Perspective on LDL Movement and Atherosclerosis 1:17:33 Exploring Low Cholesterol Impacts and Genetic Disorders 1:22:30 Macrophage Function and Phenotype Across Different ApoB Drivers 1:31:41 Defining Lean Mass Hyper Responders in the Context of a Ketogenic Diet 1:38:00 Investigating PCSK9 and Its Effects on Healthspan 1:44:18 Assessing cardiovascular risk in lean mass hyper-responders 2:02:19 Statin safety, adverse effects, and patient reluctance 2:11:10 Ketogenic Diets and Elevated LDL: Risks and Benefits in the Absence of Long-Term Data 2:18:40 Insulin Resistance, ApoB, and Cardiovascular Risk: Challenges in Assessment and Imaging 2:33:06 Lean Mass Hyper-Responder Study: Design, Recruitment, and Eligibility Criteria 3:05:15 Outro Enjoy, friends. Simon This episode is brought to you by: InsideTracker If you want to improve your health, you need to measure where you’re currently at. InsideTracker analyses up to 48 blood biomarkers including ApoB, LDL, HDL, A1C, and more before giving you advice to optimise your health. Get a 20% discount on your first order at insidetracker.com/simon http://insidetracker.com/simon. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at http://shopify.com/proof Sun Home Saunas Invest in your body and mind with Sun Home Saunas, pioneers in crafting premium saunas and cold plunges. Safe, effective, research-backed wellness tools to improve cardiovascular health, offer psychological benefits, and reduce muscle soreness. Head to http://sunhomesaunas.com/theproof for $300 off your purchase. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com http://eimele.com/ and use code SIMON at checkout for 10% off your first order. Simon Hill, MSc, BSc (Hons) Creator of http://theproof.com/ and host of The Proof with Simon Hill https://theproof.com/podcast/ Author of The Proof is in the Plants https://theproof.com/book/
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Bariatric surgery prepared me for glp1 medications by applying certain lifestyle changes. For any of my post bariatric now glp 1 friends, do you feel the same way? #glp #glp1 #glpone #glponecommunity #glp1medication #glp1journey #semaglutide #glp1forweightloss #healthandwellness #bariatricsurgery #bariatriccommunity
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Ozempic and Wegovy are used to help with diabetes, resulting in rapid weight loss, and could impact the effectiveness of birth control. For more Local News from WILX: https://www.wilx.com/ For more YouTube Content: https://www.youtube.com/channel/UC45x3YSdL5HGG8UTsIt-csw
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Strongest Belly Fat Burner | Weightloss Drink | Coffee Cinamon Extra Virgin Coconut Oil | Connect with me on my socials: https://www.facebook.com/drsadiaoffical https://www.facebook.com/drsadiaoffical https://www.instagram.com/drsadiashaikhofficial/ I’m on TikTok too! https://www.tiktok.com/@drsadia_shaikh DISCLAIMER: The information provided on this channel and its videos is for general purposes only and should Not be considered as professional advice. We have no licensed professionals or medical practitioners so always consult with your professional consultants or doctor in case you need. This video is only for General Information purposes and based on our own experience. Any information provided in this video should not be considered as a substitute for prescriptions suggested by local beauty, diet, and health care professionals. Viewers are subjected to use this information at their own risk. This channel does not take any responsibility for any harm, side effects, illness, or any health or skin care problems caused due to the use of our content or anything related to this video.
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Meghan Trainor Spills Weight-Loss Secrets: Mounjaro, Muscle Gains and Motherhood ► Click HERE to subscribe to OK! Magazine on YouTube: https://www.youtube.com/channel/UCMqutOY_MK1F26YW77GTytQ?sub_confirmation=1 ► Click HERE to sign up for OK! Magazine’s newsletter: https://okmagazine.com/newsletter-signup/ ► Click HERE to subscribe to OK! Magazine’s up-to-the-minute breaking news podcasts: https://redcircle.com/show/389429ec-a085-40a0-897c-b26352f34565 Connect with OK! Magazine on social media: https://twitter.com/OKMagazine https://www.instagram.com/okmagazine/ https://www.facebook.com/okmagazine/
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Join Ellen Csepe to discuss how GLP1 medications impact fracture risk! Spoiler alert 🚨 it's more complicated than you may think! Want to make sure you stay on top of all things geriatrics? Go to https://MMOA.online to check out our Free eBooks, Lectures, & the MMOA Digest! check out the research charcuterie board below! https://search.app/hERQ8vkqUGfNUV6z8 https://search.app/k3LNHCykgu5rd8Go9 https://www.thelancet.com/journals/landia/article/PIIS2213-8587(21)00203-5/abstract
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👇🏻TREINE COMIGO👇🏻 ✅LISTA DE ESPERA PROJETO GRIDNODE para um corpo forte, definido e resistente SEM ACADEMIA - 23/01 https://chat.whatsapp.com/LFEDWS3dMvgBYmszZIvfEY https://chat.whatsapp.com/LFEDWS3dMvgBYmszZIvfEY https://chat.whatsapp.com/LFEDWS3dMvgBYmszZIvfEY _____________________________ 💊Creatina, Ômega 3, Cloreto de magnésio, Vitamina D3 e Whey 👇🏻 https://www.gsuplementos.com.br/ | cupom "CUNHA" no carrinho dá ATÉ 14% de desconto ↑ Growth Supplements ↑ _____________________________ CONTATO E CURSOS: 🌍 Ferramentas, Serviços e Cursos: https://cunhov.site/?page_id=384 E-mail para contato: [email protected] _____________________________ 📸 INSTAGRAM - https://www.instagram.com/cunhov/ ______________________________________ 00:00 - Deixa o like 00:15 - Se inscreva 00:30 - Links importantes na descrição 📈Ajude o nosso canal a crescer: COMPARTILHE ESTE VÍDEO! (É de graça! :D) Nota: O meu objetivo aqui é apenas informar e mostrar o que aprendi com muito estudo e dedicação. Vejo que existe muita informação distorcida semeada na internet e quero apenas ajudar! Nenhuma orientação aqui presente deve substituir uma consulta a um profissional formado e licenciado. Não façam atividades físicas, musculação e dietas sem acompanhamento profissional. Ozempic provavelmente é o remédio mais conhecido da atualidade. Mas curiosamente, o motivo pelo qual ele foi inventado não é o motivo pelo qual se tornou popular. Originalmente um remédio para diabetes, hoje o Ozempic é usado por milhões de pessoas no mundo todo para auxiliar na perda de peso. Mas será que isso tudo vem sem efeitos colaterais? Nós precisamos falar sobre o Ozempic. Leslie M. Hot weight loss drugs tested against addiction. Science. 2023 Sep;381(6661):930-931. doi: 10.1126/science.adk5720. Rubin R. Could GLP-1 Receptor Agonists Like Semaglutide Treat Addiction, Alzheimer Disease, and Other Conditions? JAMA. 2024;331(18):1519–1521. doi:10.1001/jama.2024.1017 Qeadan F, McCunn A, Tingey B. The association between glucose-dependent insulinotropic polypeptide and/or glucagon-like peptide-1 receptor agonist prescriptions and substance-related outcomes in patients with opioid and alcohol use disorders: A real-world data analysis. Addiction. 2024. https://doi.org/10.1111/add.16679 Egecioglu E, Engel JA, Jerlhag E. The glucagon-like peptide 1 analogue, exendin-4, attenuates the rewarding properties of psychostimulant drugs in mice. PLoS One. 2013 Jul 16;8(7):e69010. doi: 10.1371/journal.pone.0069010. PMID: 23874851; PMCID: PMC3712951. Herman RJ, Hayes MR, Audrain-McGovern J, Ashare RL, Schmidt HD. Liraglutide attenuates nicotine self-administration as well as nicotine seeking and hyperphagia during withdrawal in male and female rats. Psychopharmacology (Berl). 2023 Jun;240(6):1373-1386. doi: 10.1007/s00213-023-06376-w. Epub 2023 May 2. PMID: 37129617; PMCID: PMC11088902. Chuong V, Farokhnia M, Khom S, Pince CL, Elvig SK, Vlkolinsky R, Marchette RC, Koob GF, Roberto M, Vendruscolo LF, Leggio L. The glucagon-like peptide-1 (GLP-1) analogue semaglutide reduces alcohol drinking and modulates central GABA neurotransmission. JCI Insight. 2023 Jun 22;8(12):e170671. doi: 10.1172/jci.insight.170671. PMID: 37192005; PMCID: PMC10371247.