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In a country where over 250 million people struggle with excess weight, weight loss drugs like Wegovy and Mounjaro are making headlines and reshaping the Indian pharma landscape. Explore how these breakthrough medicines work, why their high price hasn’t stopped demand, and what will happen when affordable generics hit the market in 2026. This story digs deep into the science, market boom, future of obesity care, and the crucial balance between medicine and a healthy lifestyle. #weightloss #IndiaPharma #wegovy #mounjaro #ObesityRevolution #weightlossjourney
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After activation by full agonists such as GLP-1,GLP-1R(1)couples with Gas activates adenolate cyclase(AC),and causes the accumulation of cAMP.With increasing cAMP levels, protein kinase A（PKA） and the exchange protein directly activated by cAMP-2(Epac-2) are also activated. PKA and Epac-2 trigger the closure of KATP and KV channels,which depolarizes the cell membrane opens voltage-dependent Calcium channels(VDCC) and causes Calcium influx and the promotion of insulin secretion by the islet beta cells. https://www.medicilon.com/platform/glp-1/
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