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Brief review of pharmacotherapy of GLP-1 RA and SGLT2-I reminds providers that GLP-1 RA work by activating insulin synthesis and release, delaying gastric emptying, and increasing satiety. SGLT-2 inhibitors work by reducing renal tubular glucose reabsorption, increasing urinary glucose excretion, ultimately reducing serum glucose with additional weight loss and antihypertensive benefits independent of beta cell function. Review of two separate meta-analyses conclude that SGLT2-I therapy and GLP-1 RA therapy result in reduction in all-cause mortality, CV mortality, myocardial infarction, and adverse renal outcomes. Call to action for physicians and providers to routinely evaluate need for use of SGLT2-I in every patient with cardiometabolic or renal disease, not just diabetic patients, and to work closely with pharmacy teams to assist patients with medication cost barriers.
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When it comes to weight loss, many people turn to weight loss pills as a way to help shed those extra pounds. With so many options available on the market, it can be overwhelming to know which ones are the most effective. In this article, we will explore what science says about the effectiveness of various weight loss pills, so you can make an informed decision about which ones may be right for you.
The Science Behind Weight Loss Pills
Weight loss pills work in a variety of ways to help individuals lose weight. Some pills work by suppressing appetite, making you feel full so you eat less. Others may increase your metabolism, helping you burn more calories throughout the day. Some pills even block the absorption of fat in the body, leading to weight loss. It’s important to note that while weight loss pills can be effective, they are not a magic solution and should be used in conjunction with a healthy diet and exercise regimen.
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One weight loss pill that has been clinically proven to be effective is Orlistat. Also known as Alli or Xenical, Orlistat works by blocking the absorption of fat in the body. Studies have shown that individuals who take Orlistat while following a reduced-calorie diet lose more weight than those who only follow the diet alone. Another clinically proven weight loss pill is Contrave, which is a combination of naltrexone and bupropion. This pill works by decreasing appetite and increasing feelings of fullness, leading to weight loss in individuals who are obese or overweight.
Natural Weight Loss Supplements
For those who prefer a more natural approach to weight loss, there are several supplements that may be effective. Green tea extract is one such supplement that has been shown to boost metabolism and increase fat burning. Garcinia Cambogia is another popular weight loss supplement that works by inhibiting an enzyme that helps the body store fat. However, it’s important to note that the effectiveness of natural supplements can vary, and it’s always best to consult with a healthcare provider before starting any new supplement regimen.
Potential Side Effects of Weight Loss Pills
While weight loss pills can be effective, they also come with potential side effects that should be considered. Common side effects of weight loss pills may include nausea, diarrhea, constipation, and headaches. Some pills may also interact with medications or have other health risks, so it’s important to talk to your healthcare provider before starting any new weight loss pill regimen.
Conclusion
When it comes to weight loss pills, there are many options available, each with its own set of benefits and potential side effects. It’s important to do your research and consult with a healthcare provider before starting any new weight loss pill regimen. Remember, weight loss pills are not a magic solution and should be used in conjunction with a healthy diet and exercise plan for best results. By understanding the science behind weight loss pills, you can make an informed decision about which ones may be right for you.
Overall, weight loss pills can be effective when used appropriately and in conjunction with a healthy lifestyle. However, it’s essential to consider the potential side effects and consult with a healthcare provider before starting any new regimen. With the right information and guidance, you can find a weight loss pill that works for you and helps you achieve your weight loss goals.
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Diabetes drugs like Ozempic and Metformin are the source of a lot of hype online because of claims that they can induce weight loss, reverse aging and even cure cancer. Weight-loss specialist Dr. Sean Wharton and health misinformation expert Tim Caufield talk to CBC’s Asha Tomlinson about the limits and ethics of making such big claims.
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