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In this special Lunch & Learn hosted by Lipodystrophy United, Dr. Elif Oral and Dr. Maria Cristina Foss-Freitas discuss the latest research and clinical experience using GLP-1 and dual GIP/GLP-1 receptor agonists (e.g., semaglutide, tirzepatide) in treating lipodystrophy.
You’ll hear:
Real-world data from patients with FPLD, APL, and CGL
Insights into the metabolic impact of these therapies
Case studies, outcomes on triglycerides, insulin, and liver fat
Discussion on food noise, appetite regulation, GI side effects, and future clinical trials
Live Q&A with patients and caregivers
Whether you're a patient, caregiver, or clinician, this session offers valuable knowledge about emerging treatment strategies for managing hunger, body fat distribution, and metabolic symptoms in lipodystrophy.
🔗 Learn more at: www.lipodystrophyunited.org
📩 Questions? Email us at [email protected]
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Semaglutide, a medication originally used to treat type 2 diabetes, has recently gained attention for its potential as a weight loss tool. In clinical trials, semaglutide has shown impressive results in helping individuals shed pounds and improve their overall health. But how exactly does semaglutide work for weight loss in practice? Let’s take a closer look at the mechanism behind this promising drug and how it can support your weight loss journey.
The Role of Semaglutide in Weight Loss
Semaglutide belongs to a class of medications called GLP-1 receptor agonists, which work by mimicking the effects of a hormone called glucagon-like peptide-1 (GLP-1) in the body. GLP-1 is naturally produced in the intestine in response to food intake and plays a crucial role in regulating blood sugar levels, insulin secretion, appetite, and food intake.
By activating the GLP-1 receptors in the brain, semaglutide helps to reduce hunger and increase feelings of fullness, leading to a decrease in food intake. This can result in a reduced calorie intake, which is essential for weight loss. Additionally, semaglutide may also slow down the emptying of the stomach, further prolonging feelings of satiety.
Moreover, semaglutide has been shown to improve insulin sensitivity and reduce inflammation in the body, both of which are beneficial for weight management and overall metabolic health. By addressing these underlying factors, semaglutide can help individuals achieve sustainable weight loss and improve their overall well-being.
How Semaglutide is Administered
Semaglutide for weight loss is typically administered as a subcutaneous injection once a week. The starting dose is low to minimize side effects and is gradually increased over time to a maintenance dose. It is important to follow your healthcare provider’s instructions carefully and not to adjust the dosage on your own.
It is also essential to combine semaglutide treatment with healthy lifestyle modifications, such as a balanced diet and regular exercise, to achieve the best results. Semaglutide is not a magic bullet for weight loss but rather a tool to support your efforts in making sustainable lifestyle changes.
Some common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation, especially during the initial stages of treatment. These side effects usually subside as your body adjusts to the medication. However, if you experience severe or persistent side effects, it is crucial to consult your healthcare provider.
Considerations Before Starting Semaglutide
Before starting semaglutide for weight loss, it is essential to discuss with your healthcare provider about your medical history, current medications, and any underlying health conditions. Semaglutide may not be suitable for individuals with a history of pancreatitis, thyroid tumors, or certain gastrointestinal disorders.
Additionally, women who are pregnant or breastfeeding should not use semaglutide, as its safety in these populations has not been established. It is crucial to use effective contraception while on semaglutide treatment to prevent unintended pregnancy.
If you have any concerns or questions about semaglutide or its potential benefits and risks, do not hesitate to talk to your healthcare provider. They can provide personalized advice and guidance based on your individual health needs and help you decide if semaglutide is the right option for you.
Monitoring and Long-Term Success with Semaglutide
Regular monitoring of your progress and overall health is essential when using semaglutide for weight loss. Your healthcare provider may recommend periodic blood tests, weight measurements, and check-ins to assess your response to the medication and make any necessary adjustments.
It is also crucial to have realistic expectations and understand that weight loss with semaglutide may vary from person and can take time. Consistency with your treatment plan and dedication to healthy habits are key to achieving long-term success with semaglutide and maintaining your weight loss in the future.
Remember that weight loss is a journey that requires patience, commitment, and support. With the help of semaglutide and a healthcare team, you can take positive steps towards a healthier weight achieving your weight loss goals and improving your overall well-being.
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