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Coleen is back in the studio and joins Ruth, Janet and Brenda. She shares an update on life up North, including her incredible transformation and her new eating habits. From series 25, broadcast on 20/04/21 Like, follow and subscribe to Loose Women! Watch Loose Women on the ITV Hub: https://bit.ly/2Weq2CW Subscribe now for more! http://bit.ly/1VGTPwA Website: http://bit.ly/1EDGFp5 YouTube: http://bit.ly/1C7hxMy Facebook: http://on.fb.me/1KXmWdc Twitter: http://bit.ly/1Bxfxts Catch Loose Women every weekday from 12.30pm on ITV, STV and the ITV Hub. Join our panellists as they share their lives and talk about everything from friendships to relationships, parenting to politics, mental health and much, much more. Tune in to find out what your favourite Loose Women have been up to, watch exclusive interviews with showbiz stars, and get a much needed laugh at lunchtime. http://www.itv.com http://www.stv.tv #loosewomen
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Live Happy & Healthy Everyday!! How Apple Cider Vinegar helps in weight Management? What are the benefits and side effects of having apple cider vinegar. How to avoid the side effects of ACV and only take the benefits. How much apple cider vinegar to be consumed? What is the right way of having ACV? All this is explained in this video. Hope all your doubts regarding apple cider vinegar will be cleared after watching it. 😊👍 To enroll in Weight Loss Program by Gunjan Shouts, visit : https://bit.ly/3RnPdO3 Follow Gunjan on Instagram : www.instagram.com/gunjanshouts/ Subscribe to her YouTube Channel : https://youtube.com/c/GunjanShouts Subscribe to Stay Fit ► http://bit.ly/GH24by7 Like our page and follow us on Facebook - https://www.facebook.com/GoodHealth24by7 Follow and Connect with us on Instagram - https://www.instagram.com/goodhealth24by7 Follow us on Twitter - https://twitter.com/GoodHealth24by7
Ramon S Weightloss Video Log Day 52
🎙️EP282｜善纖達，猛健樂，所有GLP-1受體促效劑：減重、控糖、護心腎？從藥物比較到臨床應用全解析 — 📌主題亮點： • GLP-1受體促效劑的作用機轉是什麼？為何能兼顧控糖與體重管理？ • Tirzepatide、Semaglutide、Liraglutide 怎麼選？療效與副作用比較一次看懂 • 台灣健保給付限制、仿單外使用、心腎保護證據，全方位解析臨床現況 — 🔍內容解析： 本集重點： GLP-1受體促效劑（Glucagon-like peptide-1 receptor agonists, GLP-1 RAs）是目前糖尿病與肥胖症領域中最受矚目的藥物類別之一。這類藥物最初設計目的是控制第二型糖尿病血糖，但其延緩胃排空與降低食慾的機制，逐漸展現出優異的體重控制效果，成為減重治療的重要選項。 本集將全面比較目前臨床上常見的 GLP-1 RAs，包括 Semaglutide、Liraglutide、Dulaglutide、Exenatide、Tirzepatide 等，從作用機制、臨床療效、安全性，到心腎保護與健保給付現況，帶你掌握這波醫藥創新的核心。 — 🧩主題分段解析： — 🧬 GLP-1作用機轉：多重代謝效應的關鍵介質 GLP-1 是人體腸道於進食後釋放的一種腸泌素，具有多重生理功能： • 刺激胰島素分泌（在高血糖狀態下） • 抑制昇糖素分泌 • 延緩胃排空，增加飽足感 • 對中樞神經產生抑制食慾作用 GLP-1受體促效劑則是模擬這一生理訊號的藥物。由於天然 GLP-1 在體內迅速被 DPP-4 分解，因此這類藥物皆經修飾以延長半衰期，使其可每日或每週注射。 ⸻ 🩺 臨床療效比較：控糖與體重減輕雙重奏 根據大型隨機試驗與統合分析，GLP-1 RAs 在控制血糖（HbA1c）與體重管理上皆展現出顯著成效。 📌 各藥物臨床成效對比： 藥物名稱 HbA1c 降幅 體重減輕效果 使用頻率 核准適應症 Semaglutide -1.4 ~ -1.9% -6~15% 每週1次 第2型糖尿病、肥胖（國際核准） Tirzepatide -2.0 ~ -2.4% -10~20% 每週1次 第2型糖尿病（減重待核准） Liraglutide -1.0 ~ -1.5% -5~8% 每日1次 糖尿病、肥胖（Saxenda商品名） Dulaglutide -0.7 ~ -1.5% -2~5% 每週1次 糖尿病 Exenatide -0.8 ~ -1.0% -2~3% 每週或每日 糖尿病 其中 Tirzepatide 屬於 GIP/GLP-1 雙重受體促效劑，在 SURMOUNT 與 SURPASS 試驗中展現出前所未有的血糖控制與減重表現，有望改寫治療標準。 — 💖 心血管與腎臟保護：超越控糖的新方向 越來越多研究指出，GLP-1 RAs 除了降血糖與減重，也具有心腎保護效果，這點在糖尿病病人族群中特別重要。 📌 心血管研究亮點： • LEADER試驗（Liraglutide）： 減少 MACE（重大心血管事件）13% • SUSTAIN-6（Semaglutide）： 顯著降低心血管事件與腎功能惡化風險 • REWIND（Dulaglutide）： 在高風險群中降低中風與心臟衰竭住院率 腎臟方面，GLP-1 RAs 可延緩 eGFR 下降速度、降低蛋白尿發生，與 SGLT2i 一同被納入 CKD 病患用藥建議中（KDIGO 2022）。 — ⚠️ 常見副作用與風險考量 GLP-1 類藥物最常見的不良反應是胃腸道不適： • 噁心、嘔吐、腹瀉（劑量上升時尤明顯） • 厭食、味覺改變 此外，也需注意以下安全議題： 1. 胰臟炎風險： 少見但需警惕，特別是胰臟病史者 2. 甲狀腺 C 細胞腫瘤： 動物實驗有顯示，故有甲狀腺腫瘤病史者應避免使用 3. 低血糖風險： 單用風險低，但與 SU 類或胰島素併用時需留意 4. 腎功能不全： 輕中度 CKD 可使用，但末期腎病需個別評估 目前各大指引皆建議以「緩慢劑量上升」的方式起始治療，以改善耐受性。 — 📋 台灣市場與健保現況：法規限制與臨床建議 雖然 GLP-1 RAs 在國際間已被廣泛應用於肥胖與代謝症候群治療，但在台灣市場仍受到幾項限制： 1. 健保給付範圍有限： 僅核准用於第二型糖尿病患者，且常須 HbA1c ＞ 7.5% 且合併肥胖者 2. 體重管理為仿單外使用： 減重用途目前無正式健保核准 3. 高藥價問題： 自費族群常成經濟負擔障礙 4. 專科醫師使用限制： 多數藥品須由內分泌科或新陳代謝科開立 根據 NHIA 公告，目前 Semaglutide（Ozempic）與 Liraglutide（Victoza）皆列為給付藥品，但需符合嚴格條件。 — 🚶♀️ 臨床應用建議：如何選擇最適合的 GLP-1 受體促效劑？ 臨床選擇應考慮以下因素： • 目標： 控糖為主或減重為主？ • 用藥頻率接受度： 每日注射 vs 每週注射 • 腎功能狀況 • 副作用耐受性 • 病患偏好與經濟狀況 📌舉例： • 對減重有高度期待者：Tirzepatide ＞ Semaglutide ＞ Liraglutide • CKD早期患者：Semaglutide、Dulaglutide皆可考慮 • 容易噁心者：可考慮低劑量起始且選擇耐受性較佳者如 Dulaglutide • 自費負擔有限者：評估 Liraglutide 台灣仿單內使用是否適用 — 📣負責任的行動： GLP-1 受體促效劑不只是「減重神藥」，而是結合代謝改善、心腎保護與控糖成效的複合型療法。醫師在使用前應評估患者整體代謝風險、心血管病史與用藥習慣，避免將此藥物視為「萬靈丹」。 病患亦應接受完整衛教，了解可能副作用與正確使用方法，避免自行停藥或過度依賴。 — 📚熱門關鍵字： #GLP1受體促效劑 #Semaglutide #Ozempic #Tirzepatide #Mounjaro #Liraglutide #Saxenda #減重藥物 #糖尿病治療 #心血管保護 #腎臟保護 #胰島素促進劑 #胃排空延緩 #體重管理 #胃腸道副作用 #甲狀腺C細胞腫瘤 #台灣健保給付 #仿單外使用 #慢性腎病新療法 #糖尿病臨床指引 — 🎤主講人資訊： Dr.Happy Human Plumber｜心血管知識推廣者 擅長將複雜代謝藥物與心腎內科整合知識，轉化為清晰易懂的內容，關注台灣臨床處方趨勢與全球新藥發展，致力於提升醫病雙方的治療選擇品質。 Powered by Firstory Hosting (https://firstory.me/zh)
Weight Loss Transformation 101 Cycling Vs Running Whats Better For Burning Fat
Download the FREE HASfit app: Android http://bit.ly/HASfitAndroid -- iPhone http://bit.ly/HASfitiOS Visit http://hasfit.com/workouts/home/weight-loss-home/35-min-tabata-hiit-workout-for-fat-loss-abs/ for the 30 Min Tabata HIIT Workout for Fat Loss, Strength, Abs: Home Full Body Dumbbell Workout with Weights instructions Donate with Patreon: https://www.patreon.com/hasfit Shop HASfit Tribe store: https://hasfit.myshopify.com/ Get up to 2x Faster Results by following a Fitness Program Calendar: Which program is right for me? http://bit.ly/2E16cng Foundation Beginner Program: http://bit.ly/2AnjffQ 30 Day Muscle Building: http://bit.ly/2RqYBoO 30 Day Torch (weight loss): http://bit.ly/2VjavR5 Motive Home Athlete’s Plan (intermediate): http://bit.ly/2s09waU Warrior 90 2.0 (advanced): http://bit.ly/2QX3IxQ More programs to choose from here: http://bit.ly/2E16cng Get our Diet Guide: Eating For Life https://goo.gl/7qnHn4 Personal Training Services: http://hasfitpersonaltrainer.com Follow us for more! Facebook: https://www.facebook.com/HASFitness/ Instagram: https://www.instagram.com/hasfit_official/ Snapchat: @hasfit Twitter: https://twitter.com/HeartSoulFit Disclaimer: You should consult your physician or other health care professional before starting a HASfit program or any other fitness program to determine if it is right for your needs. This is particularly true if you (or your family) have a history of high blood pressure or heart disease, or if you have ever experienced chest pain when exercising or have experienced chest pain in the past month when not engaged in physical activity, smoke, have high cholesterol, are obese, or have a bone or joint problem that could be made worse by a change in physical activity. Do not start this fitness program if your physician or health care provider advises against it. If you experience faintness, dizziness, pain or shortness of breath at any time while exercising you should stop immediately. HASfit offers health, fitness and nutritional information and is designed for educational purposes only. You should not rely on this information as a substitute for, nor does it replace, professional medical advice, diagnosis, or treatment. If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional. Do not disregard, avoid or delay obtaining medical or health related advice from your health-care professional because of something you may have read on this site. The use of any information provided on this site is solely at your own risk. HASfit makes no warrants, promises, or claims regarding accuracy of the calories burned estimate. It is provided only as a general reference and each person should use an indirect calorimetry system for a more accurate estimate. Developments in medical research may impact the health, fitness and nutritional advice that appears here. No assurance can be given that the advice contained on HASfit will always include the most recent findings or developments with respect to the particular material.
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Want to get rid of that fat in your lower back, arms and chest? Check this 3-in-1 workout and I'm sure you'll love it! This workout will also target your core for increased mobility and will help your back along the way. It includes flexibility and strength exercises to help you burn fat and also improve your posture. It will be a perfect routine to lose stubborn fat in these areas. The Phases of this routine progressively engage different muscle groups and will ensure you the burn, similar to a full-body routine while focusing on specific areas like arms, chest and lower back. We have 5 Phases for this routine. Warm-up and Activation Phase 1 (Arm Circles, Arm Crossovers, Back Squeeze), Spinal and Core Activation Phase 2 (Cat And Cow, Back Stretch, Baby Pose), Chest and Core Strength Phase 3 (Chest Fly, Oblique Twist Squat), Lower Body and Core Strengthening Phase 4 (Walk Downs, Leg Kicks, Leg Pulls, Leg Drops), and lastly, Core Stability and Flexibility Phase 5 (Bird Dog, Knee Raises). Expect a mix of core-strengthening exercises, some upper-body toning move set and flexibility stretches that will work together to target those stubborn fats. Let's get to work and stay consistent. Good luck and have fun! ❤️💪 _**Don’t forget to share your experience and progress in the comment section. If you want to be notified when I upload a new video, make sure to subscribe to our channel. I upload new videos everyday from Monday to Saturday!_ ========================================== Stay connected on my other social media platforms so you can share your journey with others and stay motivated! *Instagram:* https://www.instagram.com/robertasgym/ *TikTok:* https://www.tiktok.com/@robertasgym *Reddit:* https://www.reddit.com/user/robertasgym/ *Twitter:* https://x.com/robertasgym *Tumblr:* https://www.tumblr.com/blog/robertasgym *Wordpress:* https://robertasgym.com/ Let’s keep the motivation going! 💪 ========================================== *TIMECODES:* 00:00 Introduction 00:08 Arm Circles 00:37 Rest 00:55 Arm Crossovers 01:29 Rest 01:47 Back Squeeze 02:33 Rest 02:51 Cat And Cow 04:35 Rest 04:53 Chest Fly 05:41 Rest 05:59 Oblique Twist Squat 06:47 Rest 07:05 Back Stretch 08:12 Rest 08:30 Baby Pose 09:36 Rest 09:55 Cobra 11:01 Rest 11:19 Walk Downs 13:21 Rest 13:39 Leg Kicks 14:06 Rest 14:24 Leg Pulls 15:04 Rest 15:22 Leg Drops 16:18 Rest 16:36 Bird Dog 17:42 Rest 18:00 Knee Raises 18:26 Rest 18:44 Walk Downs 20:46 Rest 21:04 Oblique Twist Squat 21:51 Rest 22:09 Back Squeeze 22:55 Rest 23:13 Chest Fly
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Le retatrutide fait beaucoup parler de lui comme alternative innovante au sémaglutide. Encore en phase de recherche, il montre déjà des résultats bluffants, surtout chez les athlètes ! ✨ Dans cette vidéo : • Qu’est-ce que le retatrutide ? (agoniste triple GLP-1, GIP, glucagon) • Pourquoi il agit sur plusieurs axes métaboliques pour accélérer la perte de poids • Moins de stagnation, meilleure préservation de la masse musculaire sèche • Où en sont les études ? Pourquoi c’est LA molécule à suivre en 2025 ⚠️ Disclaimer : Vidéo à but informatif. Le rétatrutide est en phase expérimentale : ne pas utiliser hors cadre médical, attendez toujours validation scientifique.