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Over a quarter of the Indian adult population is either obese, at risk of diabetes or are diabetic. This has become a marketing & business opportunity for a lot of fitness & healthtech companies with plain vanilla no science interventions focussed on either high protein, calorie counting, CGM driven or at worst GLP-1 drugs. But these companies fail to understand how human biochemistry works. These interventions, if they help in weight loss, is a stop gap arrangement. Weight gain is not the cause but the effect & symptom. Obesity is triggered by low grade chronic inflammation & our body tries its best to maintain a metabolic homeostasis. However, regular insults we do to our body by consuming toxins or ingesting those foods that are transformed by your microbiome into toxins or pro-inflammatory metabolites makes it hard for us to lose weight. Some of these metabolites include LPS, TMAO, P-cresol & more. While microbes living in our mouth & gut also produce certain beneficial metabolites & incretin hormones ( providing we are feeding them with the right food substrates) that maintain our metabolic health & make it hard for us to gain weight. One of the most important metabolites ( incretin hormone) is GLP-1. Yes, our body automatically produces GLP-1 by synthesising fibre & polyphenols in the food we eat. GLP-1 has multiple benefits via regulating various metabolic pathways-regulates blood sugar response, communicates with brain via gut-brain axis , telling that you are full & even tells stomach & intestine to slow the movement of digestive tract. However, these GLP-1 drugs which lot of companies claim mimics natural GLP-1 brings multiple side effects & just ingesting these drugs does not mean it will help you lose weight. -Effectiveness of GLP-1 drugs depends upon the functions of your microbiome. Certain microbes can synthesise these drugs into beneficial stuff that have positive correlation with glycemic reduction while some others if active & expressing virulence genes can interfere with synthesis of GLP-1 drugs . -Certain microbes if active & expressing virulence genes can degrade GLP-1, making you gain weight or develop type 2 diabetes. In such scenario, these drugs cannot help. -It has been found that obese have underexpressed NOS attributed to overexpression of tumour necrosis factor-α caused by microbial derived endotoxin LPS. Besides, there are multiple other factors that can suppress NOS/cause endothelial cell dysfunction such as overexpression of ADMA, oxidative stress( caused by P-cresol &/or Indoxyl Sulphate Production), TMAO & more. In order to understand the root cause of obesity, there is a need to understand multiple molecular pathways that trigger its onset/progression. We at Genefitletics measures these pathways to construct nutritional therapeutics interventions aligned with your biochemistry that reinstates yout metabolic homeostasis Citations https://pmc.ncbi.nlm.nih.gov/articles/PMC4112002/ https://pmc.ncbi.nlm.nih.gov/articles/PMC7021470/ https://dom-pubs.pericles-prod.literatumonline.com/doi/10.1111/dom.14725 https://pmc.ncbi.nlm.nih.gov/articles/PMC10391832/ https://diabetesjournals.org/care/article/33/2/453/27096/GLP-1-Based-Therapy-for-Diabetes-What-You-Do-Not https://pmc.ncbi.nlm.nih.gov/articles/PMC5082693/ #obesity #obesityfreeindia #obesityfreenation #obesityawareness #viralvideo #virlshort #viralreels #viral_video #viralshorts #viralnews #healthnews #healthtips #health #healthylifestyle #supplements #obesitymedicine #obesityprevention #obesityawareness #type2diabetes #diabetesawareness #diabetesmanagement #diabetescare #diabetescure
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This is my weigh in for week 2 on Mounjaro, weigh with me! Take a drink of water everytime I say "absolutely"! 0:00 Alcohol free and attending a concert (Elton John and Brandi Carlisle at the London Palladium) 2:40 Weigh in 3:48 exercise 8:38 Mounjaro effects - food noise / hunger suppression / cravings 10:40 What Mounjaro has taught me - over eating. What have you learned on using a GLP 1? 12:26 Pace of weight loss and body composition - losing muscle mass #mounjaro #weightlossinjections #glp1medication
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This is what this fatty eats in a day to lose 20kg and build muscle on Wegovy by summer #WegovyWeightLoss #WhatIEatInADay #GLP1 #MuscleGain ✨ Wegovy Update: 7 June 2025 ✨ Weight: 83.85kg (No weigh-in, likely unchanged - but we shall see when I am back in Stockholm). Total Lost on Wegovy: 16.25kg! 🎯 Goal: 80kg by 30 June! 🎯 Just 3.85kg to go in 23 days on my Wegovy plan for a 20kg total loss! 📝 What I Actually Ate Today 📝 Today was officially my first day in Istanbul! Morning: Had some bruschettas with some cheese. At the beach: Had a lot of snacks - a croissant, some crisps, and a banana. Later Snack: I also had a pear. Dinner: Had some chicken boneless wings (I did not eat the whole thing). 💡 Key Wins & Wegovy Thoughts 💡 Macros check: 1,026 calories in excess. Fat was a bit too much over. Protein was okay but not enough for how much I've eaten. Carbs and fibre were okay. 📣 Join My Wegovy Journey! 📣 Follow for daily WIEIAD, real Wegovy talk & the push to 80kg! Your top nutrition win this week? 👇 #WegovyWeightLoss #WhatIEatInADay #GLP1Journey #MuscleBuildingJourney #WeightLoss #Wegovy #GLP1 #FatLoss #ProteinFocused #CalorieDeficitLife #MacroTracking #Semaglutide #WeightLossMotivation #FitnessJourney #HighProteinMeals #FoodDiary #TransformationJourney #ProgressOverPerfection #WegovySupport #WIEIAD
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Bye Bye Belly Fat With My Easy Standing Abs Workout For Beginners To Lose Belly Fat At Home , These belly fat exercises are so easy you can easily do it at home without any equipment. This is a No Jumping , Low Impact Belly Fat Workout to get a flat tummy and a slim waist in the comfort of your home , so this home workout in front on your Tv or while in a park , just do it anywhere do see amazing results. I am Natasha Mohan , Always remember to pair all your workouts with a calorie deficit diet to get best results. #standingabsworkout #bellyfat #bellyfatworkout #bellyfatexercises #weightlosswithnatashamohan
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Like mother, like daughter 💋 Christina Aguilera will release a live studio re-imagining of her debut album’s hits on September 23, which will feature a collab with pop music’s newest star Sabrina Carpenter » Sign up for our newsletter KnowThis to get the biggest stories of the day delivered straight to your inbox: https://go.nowth.is/knowthis_youtube » Subscribe to NowThis: https://go.nowth.is/Main_Subscribe For more stories like this, subscribe to @NowThis. #ChristinaAguilera #SabrinaCarpenter #Music #Shorts #NowThis Connect with NowThis » Like us on Facebook: https://go.nowth.is/Main_Facebook » Connect with us on Twitter: https://go.nowth.is/Impact_Twitter » Follow us on Instagram: https://go.nowth.is/Main_Instagram » Find us on Snapchat Discover: https://go.nowth.is/Impact_Snapchat NowThis is your premier media outlet providing you with all the content you need to stay up to date. From entertainment to viral videos and trending stories, NowThis is delivering all you need to know straight to your social feeds. We live where you live. http://www.youtube.com/@nowthis @nowthis
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Gained Muscle While Losing Fat 💪 #weightloss #food #caloriecounting #fatlosstips #healthyfood #diet #weightloss #weightlosshelp #flexibledieting #countingcalories #countingmacros #buildingmuscle #bulkingfood #highprotein #weightlossrecipes #lowcaloriemeals #lowcalorierecipes #fatlosstips #myfitnessjourney
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