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GLP-1 is secreted by intestinal cells in response to glucose ingestion and acts on the vagus nerve and hypothalamus to induce satiety. Subscribe to Nourishable at https://www.youtube.com/c/Nourishable
This video is part 6 of the Neurobiology of Food Intake module within a lecture series on the nutrition science of macronutrients.
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References
Klockars, A. et al. Hypothalamic Integration of the Endocrine Signaling Related to Food Intake. Curr. Topics Behav. Neurosci. (2019) 43:239-270
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Glucagon-like peptide 1, or GLP-1, is a hormone secrets by the L cells in the intestine in response to glucose ingestion in proportion to consumed calories. GLP-1 stimulates insulin secretion from the pancreas to prepare the body for high blood glucose levels - this makes it an incretin because it increases insulin. Further, GLP-1 inhibits glucagon. GLP-1 binds to chemoreceptors on the vagus nerve to activate the vagus to send afferent signals to stimulate the nucleus tractus solitarius in the hindbrain to stimulate satiety. GLP slows gastric emptying which keeps the GI tract stretched and distended for longer - this activates the stretch-sensitive mechanoreceptors on the vagus to additionally stimulate the NTS. GLP-1 crosses the blood-brain-barrier of the hypothalamus to activate the POMC neurons in the arcuate nucleus. POMC neuron stimulation causes release of the neurotransmitter alpha MSH which stimulates the paraventricular hypothalamus to induce satiety. GLP-1 also inhibits the orexigenic AgRP neurons. GLP-1 is an anorexigenic, satiety-inducing hormone.
My Weightloss Journey 40lbs Natural Lifter
As the obesity epidemic continues to rise globally, more and more people are seeking out weight loss clinics offering innovative solutions to help them achieve their goals. One such treatment gaining popularity is the use of Semaglutide, a medication originally used to treat type 2 diabetes but now being prescribed off-label for weight loss. If you are considering finding a weight loss clinic offering Semaglutide near you, it is important to choose the right facility that can provide safe and effective treatment options tailored to your individual needs.
Researching Weight Loss Clinics
When looking for a weight loss clinic offering Semaglutide, the first step is to research different facilities in your area. Start by checking online reviews, asking for recommendations from your healthcare provider, and looking into the credentials of the clinic’s medical staff. You want to ensure that the clinic you choose has a good reputation and experienced professionals who can guide you through your weight loss journey.
Additionally, consider the location and convenience of the clinic. You will likely be making regular visits for check-ins and monitoring, so it’s important to choose a clinic that is easily accessible to you. You may also want to inquire about the clinic’s hours of operation and scheduling flexibility to ensure it fits into your lifestyle.
During your research, take the time to learn about the specific weight loss programs and treatments offered at each clinic. Some facilities may specialize in certain approaches, such as medically supervised weight loss plans, lifestyle coaching, or prescription medications like Semaglutide. Choose a clinic that aligns with your preferences and goals for weight loss.
Consultation and Assessment
Once you have narrowed down your options, schedule consultations with the weight loss clinics you are interested in to learn more about their approach to Semaglutide treatment. During these consultations, you can discuss your weight loss goals, medical history, and any concerns you may have about starting Semaglutide.
The clinic’s medical staff will likely conduct a thorough assessment of your current health status to determine if Semaglutide is a suitable treatment option for you. They may check your body mass index (BMI), blood pressure, cholesterol levels, and other relevant health markers to tailor a personalized weight loss plan that includes Semaglutide.
It’s important to ask questions during the consultation to ensure you fully understand the treatment process, potential side effects, and expected results. Be honest and transparent with the medical team about your lifestyle habits, medication use, and any underlying health conditions to receive the best possible care.
Treatment Plan and Monitoring
After choosing a weight loss clinic and starting Semaglutide treatment, you will work with the medical team to develop a comprehensive treatment plan that includes regular monitoring and support. Semaglutide is typically prescribed as a once-weekly injection that helps control appetite and regulate blood sugar levels to promote weight loss.
Throughout your treatment, the clinic’s healthcare providers will monitor your progress, adjust your medication dosage as needed, and provide guidance on diet and exercise to maximize the benefits of Semaglutide. They will also be available to address any concerns or questions you may have about the treatment and support you every step of the way on your weight loss journey.
It’s essential to follow the treatment plan outlined by your healthcare providers and attend all scheduled appointments for monitoring and evaluation. By staying consistent and committed to your weight loss goals, you can achieve long-lasting results with Semaglutide and the support of a dedicated weight loss clinic.
Long-Term Success and Maintenance
As you progress through your weight loss journey with Semaglutide, the weight loss clinic will help you transition into the maintenance phase to sustain your results and prevent weight regain. They may offer ongoing support, resources, and guidance on healthy lifestyle habits to ensure your success in the long term.
It’s important to stay connected with your healthcare providers even after reaching your weight loss goals to continue monitoring your progress and address any challenges that may arise. By maintaining open communication with the clinic and staying accountable to your weight loss plan, you can enjoy a healthier and happier life with the support of Semaglutide and a trusted weight loss clinic.
Remember that weight loss is a journey that requires dedication, patience, and the right support system. By choosing a reputable weight loss clinic offering Semaglutide near you and following a personalized treatment plan, you can achieve your desired weight loss goals and improve your overall health and well-being.
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Weight loss is a topic that has been heavily discussed and debated for decades. With the rise of obesity rates around the world, many people are looking for quick and easy solutions to shed those extra pounds. One of the most popular methods for weight loss is through the use of weight loss pills. These pills claim to help individuals lose weight quickly and effortlessly without having to make drastic changes to their diet or exercise routine.
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Before diving into the world of weight loss pills, it is important to understand how they work. Most weight loss pills work by either suppressing appetite, increasing metabolism, or interfering with the body’s ability to absorb certain nutrients. Some pills contain ingredients that have been shown to aid in weight loss, such as caffeine, green tea extract, and Garcinia Cambogia. However, it is essential to note that not all weight loss pills are created equal, and some may have harmful side effects or interactions with other medications.
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Choosing the Right Weight Loss Pill for You
With so many weight loss pills on the market, it can be challenging to know which ones are safe and effective. Before starting any weight loss pill regimen, it is essential to do your research and consult with a healthcare professional. They can help you determine which weight loss pill is best suited for your body and weight loss goals. Additionally, reading reviews and testimonials from other users can provide valuable insight into the effectiveness of a particular weight loss pill.
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The Truth About Weight Loss Pills
While weight loss pills can be a helpful tool for some individuals, they are not a magic solution for weight loss. In order to lose weight and keep it off, it is essential to make sustainable lifestyle changes such as eating a healthy diet, exercising regularly, and managing stress. Weight loss pills should be used in conjunction with these healthy habits, not as a substitute for them. Additionally, weight loss pills are not suitable for everyone and may not be safe for individuals with certain medical conditions or pregnant women.