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Wegovy (semaglutide) has been heralded as a revolutionary new weight loss drug, in this video I share everything you need to know about this GLP-1 receptor agonist (Saxenda / Ozempic alternative); how it works, the pros, cons and side effects.
We are coming to understand more and more about how obesity is a complex, chronic disease with multifactorial causes, so it is too simplistic to think that one medication may solve our obesity problems, but I am pleased that it is acknowledging the metabolic disturbance associated with obesity. Ultimately, we need change on a societal level, but this is not a bad start for those seeking to improve their health and lose weight!
Please note, I state that patients lost on average '12% body fat' compared to placebo, but actually it is 'body weight'.
Published 19th February 2023. Due to bz reviewed April 2026
References:
https://www.nice.org.uk/news/article/nice-recommends-new-drug-for-people-living-with-obesity
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Semaglutide is a medication that has been gaining popularity for its effectiveness in weight loss. It belongs to a class of drugs called GLP-1 receptor agonists, which work by mimicking the effects of a hormone called glucagon-like peptide-1 (GLP-1) that is produced in the gut. GLP-1 helps regulate blood sugar levels, insulin production, and appetite. Semaglutide is primarily used to treat type 2 diabetes, but studies have shown that it can also help promote weight loss in people with obesity.
How Does Semaglutide Promote Weight Loss?
One of the main ways that Semaglutide promotes weight loss is by increasing feelings of fullness and reducing hunger. It slows down the rate at which food empties from the stomach, which can help control appetite and reduce overall calorie intake. Additionally, Semaglutide has been shown to reduce cravings for high-calorie and high-fat foods, making it easier for people to make healthier food choices.
Another way that Semaglutide helps with weight loss is by improving insulin sensitivity and reducing insulin resistance. Insulin resistance is a condition in which the body’s cells do not respond properly to insulin, leading to high blood sugar levels and weight gain. By improving insulin sensitivity, Semaglutide helps the body use glucose more effectively, which can lead to weight loss.
Moreover, Semaglutide may also increase the body’s energy expenditure, or the number of calories burned at rest. This can help boost weight loss by creating a calorie deficit, where the body burns more calories than it consumes. By increasing energy expenditure, Semaglutide can help people lose weight more effectively and maintain weight loss over time.
Potential Side Effects of Semaglutide
While Semaglutide can be an effective weight loss medication, it is important to be aware of potential side effects. Some common side effects of Semaglutide include nausea, vomiting, diarrhea, and constipation. These side effects usually improve over time as the body adjusts to the medication, but it is important to talk to your doctor if you experience persistent or severe side effects.
In rare cases, Semaglutide may also cause more serious side effects, such as pancreatitis or thyroid tumors. It is important to discuss the risks and benefits of Semaglutide with your doctor before starting treatment. Your doctor can help monitor for any potential side effects and adjust your treatment plan as needed to ensure your safety and well-being.
Additionally, Semaglutide may interact with other medications or supplements you are taking, so it is important to provide a comprehensive list of all medications and supplements to your doctor before starting Semaglutide. Your doctor can help determine if Semaglutide is the right choice for you and recommend any necessary adjustments to your treatment plan.
Is Semaglutide Right for You?
If you are struggling to lose weight and have not had success with diet and exercise alone, Semaglutide may be a suitable option for you. It is important to talk to your doctor about your weight loss goals and any underlying health conditions you may have before starting Semaglutide. Your doctor can help determine if Semaglutide is a safe and effective choice for you based on your individual needs and medical history.
Semaglutide is typically prescribed as a once-weekly injection that can be self-administered at home. Your doctor will provide specific instructions on how to use Semaglutide, including the correct dosage and injection technique. It is important to follow your doctor’s instructions carefully to ensure the medication is effective and to minimize the risk of side effects.
In conclusion, Semaglutide is a popular medication for weight loss that works by increasing feelings of fullness, improving insulin sensitivity, and increasing energy expenditure. While it can be an effective tool for weight loss, it is important to be aware of potential side effects and to discuss the risks and benefits of Semaglutide with your doctor. If you are considering Semaglutide for weight loss, talk to your doctor to determine if it is the right choice for you and to create a personalized treatment plan.
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DISCLAIMER
Please note: This video clip is created as part of an educational assignment on the basis of my knowledge gained from books and different sources and should be treated as such. Please do not treat it as a medical advice. Always seek the advice of your physician or other qualified health providers prior to starting any new diet or treatment and with any questions you may have regarding a medical condition. If you have or suspect that you have a medical problem, promptly contact your health care provider. Thank you and best of luck.
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