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On this episode of the She’s Healthy podcast your host and Nurse Practitioner, Lori Aikman, looks at the research to see… Which is better for weight loss semaglutide (Wegovy) or tirzepatide (Zepbound)? If you're a woman who is struggling to lose weight, maybe all the things you used to do like diet and exercise aren't working and you're looking for more. If you're considering taking one of these medications to help your stubborn weight loss, this is an episode you won't want to miss. Key Takeaways: Mechanism of Action: Lori reviews how both semaglutide and tirzepatide work to induce weight loss. If you missed the details, check out the first episode for an in-depth discussion. Approval Timeline: Semaglutide received FDA approval for treating obesity before tirzepatide. Tirzepatide was FDA approved for obesity on 11/8/23. Clinical Trials: Explore the results of the STEP trials, focusing on semaglutide's effectiveness for obesity. Learn about the SURPASS trials that studied tirzepatide's impact on patients with diabetes, and get a sneak peek into the upcoming SURMOUNT trials examining tirzepatide's efficacy for obesity in both diabetic and non-diabetic patients. Pharmaceutical Source: Both semaglutide and tirzepatide injections are products of the renowned pharmaceutical company, Eli Lilly. Prescribing Guidelines: Understand the obesity prescribing guidelines, emphasizing that these medications are intended for individuals with a BMI greater than 30 or a BMI greater than 27 with weight-related comorbidities such as diabetes, pre-diabetes, high blood pressure, high cholesterol, cardiovascular disease, etc. SURMOUNT-1 Trial: Delve into the findings of the SURMOUNT-1 trial, exploring the effectiveness of various tirzepatide doses compared to a placebo for weight loss. Discover that weight loss increases with higher doses of tirzepatide. Comparison Study: Gain insights from the study "Weight loss with subcutaneous semaglutide versus other glucagon-like peptide 1 receptor agonists in type 2 diabetes." Find out how tirzepatide outperformed semaglutide, dulaglutide, exenatide, and liraglutide in terms of weight loss. Appetite Reduction: Uncover takeaways from the study "Tirzepatide Reduces Appetite, Energy Intake, and Fat Mass in People With Type 2 Diabetes." Cost-Effective Options: Lori suggests a cost-effective alternative – getting these medications from a compounding pharmacy. Whether you're on a weight loss journey or simply curious about these medications, Lori provides valuable insights to guide your decisions. Tune in to the She’s Healthy podcast and stay informed about optimizing your health in your 30s and 40s! Curious about working with Lori? Click here to book a 15 Minute Connection Call: https://crownexecutivehealth.practicebetter.io/#/631766a4a7504499f968aef3/bookings?s=63f18e116f764b1753415af8 Check out the website: http://www.queenbeemedicine.com Follow us on Instagram: https://www.instagram.com/queenbeemedicine/ https://www.instagram.com/loriaikman/

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Semaglutide is a medication originally developed for the treatment of type 2 diabetes. However, recent studies have shown that it can also be an effective treatment for weight loss. Semaglutide works by mimicking the effects of a hormone called glucagon-like peptide-1 (GLP-1), which helps regulate blood sugar levels and appetite. When used at higher doses, semaglutide has been shown to reduce food cravings, increase feelings of fullness, and ultimately lead to weight loss.

Semaglutide Dosage for Weight Loss

When it comes to using semaglutide for weight loss, the dosage is crucial. The typical dosage of semaglutide for diabetes is around 1-2 mg per day. However, for weight loss purposes, a higher dosage is usually required. Studies have shown that a dosage of 2.4 mg per day of semaglutide is the most effective for significant weight loss results. This higher dosage helps to suppress appetite even more effectively, leading to greater weight loss outcomes.

It’s important to note that semaglutide should always be used under the supervision of a healthcare provider to ensure safety and effectiveness. Your doctor will determine the appropriate dosage for your specific weight loss goals and needs. They will also monitor your progress and make any necessary adjustments to the dosage as needed.

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Potential Side Effects of Semaglutide

Like any medication, semaglutide does come with potential side effects. Some common side effects of semaglutide for weight loss may include nausea, vomiting, diarrhea, and constipation. These side effects usually improve over time as your body adjusts to the medication. However, if you experience severe or persistent side effects, it’s important to contact your healthcare provider.

In rare cases, semaglutide may also cause more serious side effects such as pancreatitis or thyroid tumors. It’s essential to be aware of the signs and symptoms of these potential complications and to seek medical attention if you experience them. Your doctor will monitor you for any signs of these rare side effects during treatment with semaglutide.

Tips for Success with Semaglutide

While semaglutide can be a powerful tool for weight loss, it’s essential to combine it with healthy lifestyle habits for the best results. Eating a balanced diet, staying active, getting enough sleep, and managing stress are all key components of a successful weight loss journey. Semaglutide can help suppress your appetite and make it easier to stick to a healthy eating plan, but it’s important to make sustainable lifestyle changes for long-term success.

Additionally, regular check-ins with your healthcare provider can help keep you on track and motivated. They can provide support, guidance, and make any necessary adjustments to your treatment plan. Remember that weight loss is a journey, and it’s essential to be patient and persistent in your efforts. With the right combination of semaglutide, lifestyle changes, and support, you can achieve your weight loss goals and improve your overall health and well-being.

Conclusion

In conclusion, semaglutide can be an effective treatment for weight loss when used at the appropriate dosage under the guidance of a healthcare provider. By suppressing appetite and helping regulate blood sugar levels, semaglutide can lead to significant weight loss results. Remember to stay consistent with your treatment plan, follow healthy lifestyle habits, and seek support from your doctor to maximize the benefits of semaglutide for weight loss.

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