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(13 Jun 2007) HEADLINE: Federal health panel rejects weight-loss drug --------------------------------------- CAPTION: A Food and Drug Administration panel unanimously rejected a closely watched weight-loss drug from Sanofi-Aventis SA, on concerns the drug increases the number of psychiatric events like depression and suicidal thinking among users. (June 13) ---------------------------------------- [Notes:ANCHOR VOICE] [Notes:VO --SHOTS OF PANEL] A FEDERAL HEALTH ADVISORY PANEL HAS UNANIMOUSLY REJECTED A NEW WEIGHT-LOSS DRUG AFTER HEARING TESTIMONY THAT THE DRUG CAN CAUSE PSYCHIATRIC PROBLEMS. TESTS FIND IT CAN INCREASE THE RISK OF SUICIDAL THOUGHTS, EVEN AMONG PATIENTS WHO HAVE NO HISTORY OF DEPRESSION. [Notes:VO --SHOTS OF DRUG] THE DRUG IS CALLED RIMONABANT (rih-MOAN-uh-bant) -- AND IT'S MANUFACTURED BY SANOFI-AVENTIS (sih-NO-fee uh-VEHN-tiss). IN STUDIES -- PATIENTS WHO RECEIVED THE TABLET ONCE DAILY REPORTED TWICE AS MANY PSYCHIATRIC SIDE EFFECTS -- INCLUDING DEPRESSION AND ANXIETY --- AS THOSE WHO RECEIVED A SO-CALLED 'SHAM' TREATMENT. [Notes:SOT --] 'i think these psychiatric side effects are prevalent...some of them are quite significant. [Notes:SOT --] 'I have very high concern about the safety data. When you look at the lifetime animal studies, it's clear we need more longterm data in humans" [Notes:VO -- SHOTS OF DRUG] ALTHOUGH THE DRUG IS CURRENTLY MARKETED IN EUROPE, IT'S NOT YET AVAILABLE IN THE U.S. THE PANEL TOOK TWO VOTES -- AND UNANIMOUSLY VOTED AGAINST IT BOTH TIMES -- MAKING IT UNLIKELY THE F-D-A WILL APPROVE IT. BUT THE AGENCY IS SET TO MAKE A FINAL DECISION IN LATE JULY. [Notes:SOT] people who are overweight and obese are desperate, desperate for any measure (cut) word spreads like wildfire.' [Notes:SOT] 'we are going to have massive use of the drug and we just have small group of people for two year study, yet this is presented as a drug that's going to be lifetime. [Notes:VO] THE MANUFACTURER ADMITS THE DRUG IS NOT APPROPRIATE FOR PEOPLE WITH A HISTORY OF DEPRESSION. IT ALSO SAYS DOCTORS SHOULD SCREEN PATIENTS FOR DEPRESSION BEFORE WRITING A PRESCRIPTION. EXPERTS SAY EVEN IF THE F-D-A DOES APPROVE THE DRUG, IT WOULD LIKELY COME WITH STERN WARNINGS -- WHICH IS SOMETHING THE MANUFACTURER EMBRACES Find out more about AP Archive: http://www.aparchive.com/HowWeWork Twitter: https://twitter.com/AP_Archive Facebook: https://www.facebook.com/APArchives  Instagram: https://www.instagram.com/APNews/ You can license this story through AP Archive: http://www.aparchive.com/metadata/youtube/266938bc4e3a5a170656de2ca93b9571
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Get the 5 Tactics in My Longevity Toolkit and my weekly newsletter here (free): https://bit.ly/4hxPsn6 Watch the full episode: https://youtu.be/NU98SXBCjz4 Become a member to receive exclusive content: https://bit.ly/3O0pEnY This clip is from episode 333 ‒ Longevity roundtable—the science of aging, geroprotective molecules, & lifestyle interventions with Steven Austad, Ph.D., Matt Kaeberlein, Ph.D., Richard Miller, M.D., Ph.D. In this clip, they discuss: - The potential geroprotective effects of GLP-1 receptor agonists, particularly beyond caloric restriction, and their possible role in dementia prevention. - Challenges in testing GLP-1 drugs in mice due to labor-intensive protocols and the need for oral formulations for easier administration. - The broader economic implications of GLP-1 drugs, including their potential to extend healthspan, increase workforce longevity, and reduce healthcare costs. - And more -------- About: The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more. Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan. Learn more: https://peterattiamd.com Connect with Peter on: Facebook: http://bit.ly/PeterAttiaMDFB Twitter: http://bit.ly/PeterAttiaMDTW Instagram: http://bit.ly/PeterAttiaMDIG Subscribe to The Drive: Apple Podcast: http://bit.ly/TheDriveApplePodcasts Overcast: http://bit.ly/TheDriveOvercast Spotify: http://bit.ly/TheDriveSpotify Google Podcasts: http://bit.ly/TheDriveGoogle Disclaimer: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions. I take conflicts of interest very seriously. For all of my disclosures and the companies I invest in or advise, please visit my website where I keep an up-to-date and active list of such companies. For a full list of our registered and unregistered trademarks, trade names, and service marks, please review our Terms of Use: https://peterattiamd.com/terms-of-use/
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Why Your Weight Fluctuates (Even While Losing Fat) Scale Changes Explained Thanks to LMNT for sponsoring this video! Head to https://DrinkLMNT.com/michelle to get your free sample pack with any purchase. Do you have a goal body weight and are frustrated by the scale going up even when you’re eating in a calorie deficit, exercising, and doing everything right? In this video, I’ll explain why your weight fluctuates daily especially for women 35–60 who are in a fat loss phase, eating in a calorie deficit, going through perimenopause or menopause, and doing all your workouts. I will explain everything you need to know about why the scale changes not only daily, but also hourly even while losing fat. Understanding weight loss vs. fat loss, why does the scale go up and down, and having a healthy relationship with the scale, the many reasons why you weight fluctuates daily. #weightfluctuations #scalefluctuations #fatlosstips ************************************** DOWNLOAD MY FREE HIGH PROTEIN FOODS GUIDE HERE: https://michelleroots.myflodesk.com/highproteinfoodslist LEARN ABOUT MY ONLINE PERSONAL TRAINING, NUTRITION COACHING, AND ACCESS TO MY FITNESS APP https://michelleroots.com/work-with-me/ 8 WEEK BEGINNER FRIENDLY STRENGTH TRAINING PROGRAM https://michelleroots.com/8-week-stre... PROTEIN POWDER AND SUPPLEMENTS I USE AND RECOMMEND https://1stphorm.com/products/phormula-1-natural/?a_aid=michelleroots FLOURISH PROTEIN PANCAKE MIX https://flourish.rfrl.co/72884 CHECK OUT MY OTHER YOUTUBE CHANNEL WITH EXERCISE TUTORIALS & WORKOUTS @ExerciseTutorials ************************************** WATCH NEXT: FAT LOSS OVER 40 | MINDSET SHIFTS EVERY WOMAN NEEDS TO MAKE TO SEE RESULTS https://youtu.be/ye6S6QfUVLY?feature=shared HOW TO ENJOY SUMMER WITHOUT GAINING WEIGHT https://youtu.be/rDwIJEMAkX4?feature=shared LOW CALORIE HIGH PROTEIN SNACKS FOR WEIGHT LOSS OR BODY RECOMPOSITION https://youtu.be/OjbRQ0Bnflo?feature=shared 5 REASONS YOU ARE NOT GAINING MUSCLE AND LOSING FAT https://youtu.be/jbD0b9jT9YU?feature=shared ************************************** CONNECT WITH ME: Website: http://www.MichelleRoots.com & http://www.Core-Condition.com Instagram: http://www.instagram.com/michellerootsfit TikTok: https://www.tiktok.com/@michellerootsfitness Facebook: http://www.Facebook.com/MichelleRootsFit Twitter: http://www.Twitter.com/CoreCondition DISCLAIMER: Please always check with a medical professional before following any health & fitness advice including mine. These videos are for educational purposes only. AFFILIATE DISCLAIMER Note: this description contains affiliate links that allow you to find the items mentioned in this video and support the channel at no cost to you. While this channel may earn minimal sums when the viewer uses the links, the viewer is in NO WAY obligated to use these links. Thank you for your support! Train 4 Life & Be Ready 4 Anything Michelle https://www.youtube.com/watch?v=_6yeR3vk2l0
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✅OFFICIAL WEBSITE - ✅OFFICIAL WEBSITE - Keto Chews ACV Gummies Review: Unlocking the Benefits of Apple Cider Vinegar in a Delicious Form Introduction In today's world, where the pursuit of health and fitness is a common goal, innovative supplements have emerged to provide convenient solutions. One such product gaining attention is Keto Chews ACV Gummies, which aim to harness the potential health benefits of apple cider vinegar (ACV) in a tasty and chewable form. In this comprehensive review, we'll explore the key features, ingredients, potential benefits, and real-world experiences with Keto Chews ACV Gummies to determine if they're a valuable addition to your health and wellness routine. What Are Keto Chews ACV Gummies? Keto Chews ACV Gummies are a dietary supplement in the form of delicious, chewable gummies. These gummies are formulated to combine the goodness of apple cider vinegar with the principles of the ketogenic diet. The intention is to offer an accessible and enjoyable way to support various aspects of health, including weight management, digestion, and overall well-being. Pricing and Availability Keto Chews ACV Gummies are available for purchase online through various retailers and the official website of the manufacturer. The price may vary depending on the quantity and any ongoing promotions or discounts. It's advisable to check the official website for the most up-to-date pricing information. When considering the cost of Keto Chews ACV Gummies, it's essential to compare it to the price of individual components like apple cider vinegar, BHB supplements, or MCT oil. The convenience and taste of these gummies may justify a slightly higher price point for some consumers. Conclusion Keto Chews ACV Gummies provide an intriguing way to experience the potential health benefits of apple cider vinegar in a convenient and tasty form. While the ingredients in these gummies have shown promise in supporting weight management, digestive health, and ketosis induction, the extent of their effectiveness can vary among individuals. These gummies can be a valuable addition to a weight management and health regimen, particularly for those who find the taste of apple cider vinegar unappealing or who want to maintain their energy levels during ketosis. They offer a convenient and enjoyable method of incorporating ACV into your daily routine. Every 6 Bottle Package Of Keto Chews ACV Gummies Also Gets FREE Shipping! (96% Of Customers Order The 6 Bottle Bundle) #KetoChewsACVGummies #KetoChewsACVGummiesUS, #KetoChewsACVGummiesReviews, #KetoChewsACVGummiesBenefits, #KetoChewsACVGummiesBuy, #KetoChewsACVGummiesCost, #KetoChewsACVGummiesIngredients, #KetoChewsACVGummiesOrder, #KetoChewsACVGummiesPrice, #KetoChewsACVGummiesWebsite, #KetoChewsACVGummiesResults, #KetoChewsACVGummiesSideEffects, #KetoChewsACVGummiesSharkTank, #KetoChewsACVGummiesOffers, #KetoChewsACVGummiesSupplement, #KetoChewsACVGummiesBuyNow, #KetoChewsACVGummiesFormula, #KetoChewsACVGummiesHowToUse,
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