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Sara Siavoshi explains how GLP-1 medications like Ozempic are revolutionizing weight loss and improving overall health. From reducing cancer risks to being neuroprotective and anti-inflammatory, these medications provide a range of benefits. Learn how they can help with weight loss, brain health, and increase self-confidence—while keeping side effects minimal. Subscribe to Patreon for exclusive weekly content: patreon.com/ArielleLorre Looking for exclusive wellness tips, beauty hacks, and lifestyle insights you won’t find anywhere else? Subscribe to my weekly newsletter for all the inside scoop, including personal routines and healthy living tips! Don’t miss out! https://ariellelorre.com/subscribe/ Follow me: Instagram: https://www.instagram.com/well.pod/?hl=en Facebook: https://www.facebook.com/ariellelorre/ TikTok: https://www.tiktok.com/@ariellelorre?lang=en Pinterest: https://ph.pinterest.com/ariellelorre/ X: https://x.com/ariellelorre YouTube: https://www.youtube.com/@WellwithArielleLorre?sub_confirmation=1 Apple: https://podcasts.apple.com/us/podcast/well-with-arielle-lorre/id1458992375 Spotify: https://open.spotify.com/show/0vrgqp61FJYzGXJnfdv64m #GLP1 #WeightLoss #Ozempic

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This Harvard Medical School Continuing Education video examines these key questions: What role do GLP1 receptor agonists (GLP1 RA) play in weight loss? What are the risks and benefits of using GLP1 RA for weight loss? Lee-Shing Chang, MD, an endocrinologist at Brigham and Women’s Hospital, identifies FDA-approved medications for weight loss and explains GLP1 and the role GLP1 receptor agonists play in weight management. Key studies including the SCALE and STEP trials are highlighted and the efficacy of the GLP-1 receptor agonists liraglutide and semaglutide are compared. 00:00 | Introduction 00:37 | Pharmacotherapy for weight management 01:25 | What is GLP1 and what does it do? 02:35 | Clinical trials of liraglutide and semaglutide for weight loss This video was peer reviewed by Dr. Jonathan Salik, TMD, MHPEd, Instructor of Medicine, Massachusetts General Hospital; and Dr. Sugantha Sundar, MD, Assistant Professor of Anesthesia, Beth Israel Deaconess Medical Center, to validate the quality and accuracy of the content. References: Muskiet MHA, Tonneijck L, Smits MM, et al. GLP-1 and the kidney: from physiology to pharmacology and outcomes in diabetes. Nat Rev Nephrol. 2017;13(10):605-628. doi:10.1038/nrneph.2017.123 Pi-Sunyer X, Astrup A, Fujioka K, et al. A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management. N Engl J Med. 2015;373(1):11-22. doi:10.1056/NEJMoa1411892 Wilding JPH, Batterham RL, Calanna S, et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. N Engl J Med. 2021;384(11):989. doi:10.1056/NEJMoa2032183 Rubino DM, Greenway FL, Khalid U, et al. Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes: The STEP 8 Randomized Clinical Trial. JAMA. 2022;327(2):138-150. Rubino D, Abrahamsson N, Davies M, et al. Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial. JAMA. 2021;325(14):1414-1425. doi:10.1001/jama.2021.3224 Notice: At this time, the content in this video is not accredited.Tru Blu Keto Gummies A Comprehensive Review Of Tru Blu Keto

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🎧 Episode Summary: In this powerful episode of The Vitality Collective Podcast, Dr. Jeremy Bettle is joined by Christina O'Connor, a registered dietitian and gut health expert from Pendulum Therapeutics. Together, they dive deep into the science of the microbiome, exploring how trillions of organisms in our gut impact everything from metabolism and mood to immune function and long-term health. Christina shares fascinating insights into GLP-1, the gut-brain axis, postbiotics like butyrate, and why modern probiotics might be missing a key player—Akkermansia muciniphila. This conversation is a must-listen for anyone looking to optimize their gut health, naturally boost metabolism, and create a foundation for lasting vitality. 👩‍⚕️ Guest Bio: Christina O'Connor is a Registered Dietitian with extensive experience in gut health and functional nutrition. She is a clinical educator at Pendulum Therapeutics, a company at the forefront of microbiome research, known for developing innovative probiotic solutions—most notably including Akkermansia muciniphila, a strain with promising metabolic and neurological benefits. Christina’s expertise spans nutrition, functional medicine, microbiome science, and patient education, and she’s passionate about helping people heal their bodies through diet, targeted supplementation, and lifestyle interventions. 🔗 Connect with Christina & Pendulum: • 🌐 Website: www.pendulumlife.com • 🌐 Instagram: pendulumlifeco ✅ 3 Actionable Items You Can Start Today: 1. Add More Fiber – Start slowly and build up your intake with chia water, prebiotic-rich veggies (onions, green bananas), or prebiotic sodas to feed beneficial gut bacteria. 2. Prioritize Sleep – Quality sleep boosts gut repair and immune resilience. Optimize your sleep hygiene to support overall vitality. 3. Find Daily Joy – Reduce stress and promote mental wellness by doing something that genuinely brings you happiness every day. Joy is good for your microbiome too! 🔑 Key Takeaways: • The microbiome influences nearly every body system, from metabolism to mental health. • GLP-1, a powerful hormone made in the gut, impacts satiety, cravings, blood sugar, and even addiction-related brain activity. • Fiber is essential to feed butyrate-producing bacteria that help trigger GLP-1 production and support gut lining health. • Akkermansia muciniphila is a keystone strain that protects the gut barrier, supports immune modulation, and promotes metabolic health—but can’t be obtained through food or the environment. • Polyphenol-rich foods (like green tea, pomegranate, dark chocolate) are crucial for nourishing Akkermansia and other gut-friendly strains. • Fermented foods like pickled onions and kombucha add beneficial bacteria and aid digestion—but watch the sugar content. • Probiotic use after antibiotics (or even during, strategically) helps restore and protect the microbiome. • Stress weakens the gut barrier and disrupts microbial balance—simple breathing exercises can counter this. • Pendulum’s glucose control formulation has been clinically shown to improve blood sugar regulation, rivaling traditional diabetes meds like metformin. • Microbiome repair is a gradual process—give new regimens at least 3 months for real change.

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In just one month, that's 1900g of sugar—almost 2kg! That’s a big difference, right? Now, you might be thinking, "Are you recommending soda?" Definitely not—But I know many people enjoy it, myself included… so let’s be realistic. If you’re going to have one, the zero-sugar version is a much better option. It’s a small change that can make a big impact! Share with a friend who needs to know this and subscribe to fitsquadnz for fat loss tips that don't suck

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In Episode 2 of The Renew Vitality Podcast, CEO Kenneth Figueira, VP of Business Development Anderson Triggs, and Medical Director Dr. Thierry Jacquemin explore the truth behind GLP-1 weight loss medications. Together, they unpack how these groundbreaking therapies can support fat loss while preserving lean muscle, a key focus often overlooked in conventional weight loss. Drawing from both clinical experience and personal journeys, they break down the mechanisms of action, the importance of protein intake and resistance training, and why a holistic approach that includes exercise, nutrition, and targeted supplementation is essential for long-term success. If you're considering GLP-1 therapy or want to understand the real science behind sustainable weight loss, this episode is a must-listen. Timestamps: 00:00 Introduction 00:34 Personal Weight Loss Journeys 01:09 Key Principles for Effective Use of GLP-1 02:29 Understanding Metabolic Function and Weight Loss 02:54 Common Pitfalls and Misconceptions 05:35 Importance of Protein and Resistance Training 08:06 Cardio vs. Resistance Training 09:50 Sustainable Results and Individualized Treatment 21:23 Microdosing and Maintenance Doses 24:32 Mechanisms of GLP-1 and Tirzepatide 33:56 Conclusion and Contact Information Get Started: https://vitalityhrt.com/ Connect with Renew Vitality: YouTube: https://www.youtube.com/@renewvitality4159 Instagram: https://www.instagram.com/renewvitality Facebook: https://www.facebook.com/vitalityhrt TikTok: https://www.tiktok.com/@renew.vitality #GLP1 #WeightLossMedication #Tirzepatide #FatLoss #LeanMuscle #RenewVitality #MensHealth #MetabolicHealth #SustainableWeightLoss #WellnessPodcast #HormoneOptimization

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