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This animated video summarizes a network meta-analysis of randomized clinical trials comparing the effects of SGLT-2 inhibitors, GLP-1 agonists, and DPP-4 inhibitors on mortality in patients with type 2 diabetes. Read the article at: https://ja.ma/2H8FpIo.
Key Points:
Question: How do sodium-glucose cotransporter 2 (SGLT-2) inhibitors, glucagon-like peptide 1 (GLP-1) agonists, and dipeptidyl peptidase 4 (DPP-4) inhibitors compare in reducing mortality and cardiovascular events in patients with type 2 diabetes?
Findings: In this network meta-analysis that includes 236 trials with 176 310 participants, the use of SGLT-2 inhibitors or GLP-1 agonists was significantly associated with lower all-cause mortality compared with the control groups (placebo or no treatment) (hazard ratio [HR], 0.80, and HR, 0.88, respectively) and with DPP-4 inhibitors (HR, 0.78, and HR, 0.86, respectively).
Meaning: In patients with type 2 diabetes, the use of SGLT-2 inhibitors or GLP-1 agonists was associated with better mortality outcomes than DPP-4 inhibitors.
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Lizzo is officially in her weight loss era — and she's talking about how much better she feels. But what happened to the body positivity movement she helped lead?
In this video, I react to the Trisha Paytas podcast featuring Lizzo, where she opens up about her "weight release" journey. Lizzo says she feels a million times better after losing weight — but is that a complete shift from what she used to preach?
Let’s talk about the hypocrisy, the evolution, and what this means for the future of the body positivity movement.
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The way that you lose weight is NOT the way that you maintain the weight loss.
A fat loss phase is not meant to last forever. It’s not a lifestyle, it’s a strategic season where you’re intentionally focused on losing fat.
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Discover the hidden risks of Ozempic and similar GLP1 receptor agonists. Recent studies reveal a potential link between these popular weight-loss medications and increased depression and suicidal thoughts, especially in individuals with low dopamine activity. Learn about the groundbreaking research from international experts, the importance of genetic testing, and how to approach these medications safely. Don't overlook your mental well-being while pursuing weight loss goals. Watch now to understand the dual nature of GLP1 drugs and the need for personalized medicine.
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Do the popular weight-loss injections increase the risk of mental health disorders? The scientific literature analyzing the side-effects of weight-loss injections such as Ozempic and Wegovy are split on the topic. A recently published study shows a dramatic increase in the risk of mental health events involving anxiety, depression, and suicidal ideation. In this video, we review the results of this recent study as well as some anecdotal cases.
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(Repeat Circuit x3 )
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Need some inspiration to kickstart your keto journey? Look no further than the success stories featured on the GoKeto website. Real people, just like you, have shared their experiences with the ketogenic diet and how it has transformed their lives for the better. From weight loss to improved mental clarity, these stories will motivate you to stay committed to your goals.
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copyright Disclaimers:. under section 107 of the copyright act 1976, allownce is made for fair USE for purposes such as Criticism Comments , news ,reporting,scholarship ,teaching and reasearch fair use permitted by copyright status that might otherwise be infringing. non-profit educational or personal use tips the balance is favour of fair use.