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The GLP-1 Journey: Insights and Experiences from the Your Weight Matters Conference In this engaging episode, hosts Christopher and Laraine Durham bring you a special Downsized Dish interview recorded live from the Your Weight Matters conference in Arlington, Virginia. The event, organized by the Obesity Action Coalition, brings together individuals who are navigating their weight loss journeys using GLP-1 medications such as Zepbound, Mounjaro, and compounded Tirzepatide. Their guest, Mike on a Mission, shares his heartfelt story of losing 112 pounds and how these medications have changed his life. He discusses the impact of being diagnosed with type 2 diabetes, his struggles before finding these medications, and the emotional relief of realizing that obesity is a disease rather than a personal failing. Mike, a legal education strategist, delves into his experiences with social media advocacy, the importance of access to medication, and the benefits of building a supportive care team. He also talks about how his taste preferences have changed, highlighting the significant role of dietary changes and the importance of getting enough protein. Listeners will hear about the robust advocacy efforts on Capitol Hill to expand access to obesity treatments via legislative measures such as the Treat and Reduce Obesity Act. Mike emphasizes the importance of fighting for health, building a robust support system, and using social media as a tool for education and community building. They also touch upon the importance of sustainable weight loss, managing expectations, and the emotional aspects of living with and managing obesity. The episode concludes with an invitation for others to share their stories on Downsized Dish and a teaser for the upcoming Downsized cruise, promising even more community engagement and support. If you're navigating your weight loss journey and need firsthand advice and inspiration, this episode is a must-listen. ME AGAIN APP: https://apps.apple.com/us/app/meagain-glp-1-all-in-one-app/id6744178534 DOWNSIZED GLP-1 COMPANION PRODUCT STORE: https://thedownsized.org/downsized-store As an Amazon Associate I earn from qualifying purchases. DOWNSIZED WEBSITE: https://thedownsized.org/ BOOK THE DOWNSIZED AT SEA CRUISE 2026: https://thedownsized.org/downsized-at-sea-2026/ JOIN CLUB DOWNSIZED: https://www.youtube.com/@thedownsized/join FOR SPONSORSHIPS, BRAND DEALS & COLLABS: https://thedownsized.org/contact/ 00:00 Introduction and Welcome 00:22 Meet Mike: A Journey of Transformation 00:30 The Impact of GLP-1s on Daily Life 01:06 Social Media and Community Support 01:23 Personal Weight Loss Stories 01:44 Mike's Background and Struggles 02:24 The Turning Point: Discovering GLP-1s 04:36 The Emotional Journey of Weight Loss 08:30 Managing Side Effects and Dosage 17:42 Exercise and Lifestyle Changes 20:32 Diet and Taste Changes 22:06 Discussing the Best Protein Options 22:35 Morning Routine and High Protein Breakfast 23:25 The Importance of Monitoring Carbs and Glucose 23:53 Journey to TikTok and Its Impact 27:35 Advocacy and the Obesity Action Coalition 30:23 Challenges with Insurance and Medication Access 35:16 Doctors on TikTok and Their Insights 39:42 Final Thoughts and Future Plans 43:28 Conclusion and How to Connect

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Novo Nordisk seeks EMA approval for a 7.2 mg dose of Wegovy, showing 21% weight loss with strong safety data. Rhythm’s oral drug bivamelagon achieved up to 9.3% BMI reduction, boosting its stock by 36%. Yuhan expands its obesity pipeline with novel targets and monthly GLP-1 injections. MetaVia begins dosing a higher 48 mg cohort for dual agonist DA-1726. Pila Pharma raises funds for its first oral TRPV1 therapy. Allurion partners to launch its gastric balloon program in Canada with digital care support.

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