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In this episode of the Pharm So Hard Podcast, the hosts discuss GLP-1 receptor agonists, a class of medications used to manage blood sugar levels in patients with type 2 diabetes and to treat obesity. They provide an overview of the history and development of GLP-1 receptor agonists, highlighting their clinical superiority and various benefits. The hosts also explain the role of GLP-1s in the body, including their glucose-dependent insulin secretion and effects on gastric emptying. They discuss the impact of GLP-1s on hunger and mental health, emphasizing the reduction of food noise and improvement in satiety levels. Additionally, they differentiate GLP-1 receptor agonists for diabetes and weight loss and explore their indications and guideline positioning. Takeaways • GLP-1 receptor agonists are a class of medications used to manage blood sugar levels in patients with type 2 diabetes and to treat obesity. • GLP-1 receptor agonists have shown clinical superiority to other anti-hyperglycemic drugs, improving glycemic control, reducing weight loss and blood pressure, and providing cardio-protective benefits. • GLP-1s increase glucose-dependent insulin secretion, block glucagon secretion, and slow gastric emptying, leading to improved blood sugar control and increased satiety. • GLP-1 receptor agonists have a positive impact on mental health, reducing food noise and helping individuals make healthier food choices. • Different GLP-1 receptor agonists have specific indications for diabetes and weight loss, and their use is guided by clinical guidelines. • GLP-1 receptor agonists are FDA-approved for improving glycemic control in patients with type 2 diabetes and for the treatment of obesity. • The choice of GLP-1 receptor agonist depends on factors such as comorbidities, weight loss goals, and patient preferences. • GLP-1 receptor agonists have different dosing regimens, and the specific dose may vary based on the indication and the product. • Common side effects of GLP-1 receptor agonists include nausea, vomiting, and diarrhea, but these side effects often improve with continued use and proper management. GLP-1 agonists can cause loss of appetite as a side effect. • GLP-1s are being used off-label for conditions such as NAFLD and depression. • GLP-1s may have positive effects on bone health and blood pressure. • The high cost of GLP-1s poses challenges for patient access. Chapters 00:00 Introduction to GLP-1 Receptor Agonists 01:12 History and Development of GLP-1 Receptor Agonists 06:14 The Role of GLP-1s in the Body 09:38 Effects of GLP-1s on Hunger and Mental Health 11:17 Differentiation of GLP-1 Receptor Agonists for Diabetes and Weight Loss 11:44 Indications and Guideline Positioning of GLP-1 Receptor Agonists
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Tone up your dad bod in just 15 minutes with this killer bodyweight workout 💪 No gym, no excuses – let’s get those gains! Get ready to burn fat and boost your metabolism with this quick and effective 15-minute bodyweight workout that you can do anywhere! No equipment needed—just your body and a little space. This full-body fat-burning routine combines high-intensity moves that target multiple muscle groups, helping you torch calories and build strength in just 15 minutes. Perfect for beginners and advanced fitness levels alike, this workout can be done at home, in the park, or even in your office. What’s Included: - High-Intensity Interval Training (HIIT) exercises - Full-body movements to maximize fat burn - Modifications for all fitness levels Benefits: - Boosts metabolism - Improves endurance - Strengthens and tones your entire body - Convenient and time-efficient Press play and get moving! No excuses—just results. Be sure to subscribe for more quick and effective workouts! #BodyweightWorkout #FatBurning #HIIT #FitnessAnywhere #QuickWorkout #HomeWorkout #FatLoss #15MinuteWorkout #NoEquipment
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The Best Forms of Cardio for Losing Weight Not all cardio burns fat the same way. In this video, we break down the best cardio for fat loss, how much cardio you need to lose weight, when to do cardio for maximum fat burn, and how to burn fat without losing muscle. Whether it’s walking for fat loss, jump rope, HIIT, or steady-state cardio, you’ll learn how to use each method the right way — without burning out or wasting time. Want quick build tips from Brick Body? Stack up with me here: 📸 Instagram: https://www.instagram.com/brickbody.co/?utm_source=ig_web_button_share_sheet 📱 TikTok: https://www.tiktok.com/@brickbody.co?is_from_webapp=1&sender_device=pc 0:00 – The Truth About Cardio for Fat Loss 0:30 – What Type of Cardio Is Best? 1:15 – Other Cardio Options 2:00 - HIIT vs LISS 2:48 – How Much Cardio Should You Really Be Doing? 3:31 – When Should You Do Cardio? (Before or After Lifting?) 4:30 – How Cardio Helps Reveal Muscle Definition 5:28 – Why Cardio Actually Makes You Stronger 5:46 – My Wake-Up Call With Cardio 7:53 – Final Thoughts – Build Brick by Brick
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Can Ozempic truly transform your body? In this powerful 2025 update, we break down the real Ozempic before and after weight loss stories, explain the GLP-1 science behind semaglutide, share actual transformation journeys, and expose the side effects, risks, and costs of this FDA-approved diabetes drug that’s sweeping America. 🎯 Key Highlights: Real results from Ozempic users (15–20% weight loss!) Science of GLP-1 & how it suppresses hunger Side effects: nausea, “Ozempic face,” thyroid risks How much weight can you lose? What to expect month-by-month U.S. cost breakdown ($900–$1300/month) and how to save Long-term lifestyle strategies to avoid regaining weight 📢 With 137 million Americans eligible for GLP-1 weight loss drugs, you deserve facts—not hype. Whether you’re considering Ozempic, Wegovy, or Mounjaro, this full 50-minute guide gives you everything you need to make an informed choice. 💊 This is not just weight loss. This is a movement. 🔔 Subscribe for daily health tips and insights into the latest U.S. medical trends. ✅ Citations & Sources: New England Journal of Medicine, JAMA Cardiology, Obesity Journal, CDC, USDA, Harvard Health, Women’s Health, FDA, Healthline, Novo Nordisk, and more. Full list at end of video. 📌 Visit https://www.obesityaction.org for support, tools, and community. #Ozempic #WeightLoss #OzempicBeforeAndAfter #Semaglutide #GLP1 #MedicalWeightLoss #Wegovy #OzempicResults #USHealthCare #FDAApproved #DiabetesDrug #LoseWeightFast #OzempicTransformation #WeightLossJourney #OzempicFace #RealResults #HighRPM #ObesityInAmerica
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Download My Fitness App & Get 25% Off All FIO Premium Plans: https://www.fiolife.com/go-premium/FIOWITHJO SUBSCRIBE: http://bit.ly/SUBJoannaSoh | Follow my IG: https://instagram.com/joannasohofficial/ ♥ Time to go back to SCHOOL!! I know as students, sometimes you struggle to find time. Here's a short & very effective 8-minute workout to fit in your busy schedule. This will help you to study better too. 😎 ♥ LIKE, SHARE & SUBSCRIBE for exciting content every Monday, Wednesday and Friday: https://www.youtube.com/user/joannasohofficial SHARE your fitness pictures, tag me @JoannaSohOfficial #JSohActive ♥ HER Network is NOT sponsored. It's an online network I started bringing together strong, passionate and like-minded women, driven by the same vision of wanting to support other women across the world to be the best version of themselves. ♥ Joanna is a certified Personal Trainer (ACE), Women’s Fitness Specialist (NASM) and Nutrition Coach. "We aim to offer you meaningful content that will continue to add value in your life. The videos will range from health & fitness, food, lifestyle, beauty, fashion, travel, life guide, parenting, and more." Filmed at Be Urban Wellness: http://beurbanwellness.com ________________ Stay connected and follow us: https://www.instagram.com/hernetwork.tv/ https://www.facebook.com/hernetwork.tv/ Joanna Soh: http://joannasoh.com/ https://www.instagram.com/joannasohofficial/ https://www.facebook.com/joannasohofficial/ https://www.youtube.com/user/joannasohofficial https://twitter.com/Joanna_Soh (Subscribe to my website for printable workouts & recipes) ________________ This is a short and effective total body workout which you can do either first thing in the morning or before you end your day. It'll help to stretch your body, boost your metabolism and burn calories! Exercises 1) Squats / Jump Squats 2) Shoulder Tap Push-Ups 3) Lunge & Twist 4) Burpees 5) Mountain Climbers 6) Leg Kickbacks 7) Leg Lifts 8) Plank In-Out Sequence: 8 intervals (45secs Workout - 15secs Rest) Total Time: 8 minutes (1 set) You can repeat 3 - 4 to make it a full solid workout. Rest 1 minute in between set to keep your heart rate constantly elevated. To progress: - Perform 3-4 sets. - Lift some weights to make the exercises tougher or add jumps. - Choose the advance version. ________________ MORE WORKOUT VIDEOS TO GUIDE YOU THROUGH YOUR JOURNEY - 10,000 Squat Challenge in 30 Days https://youtu.be/g83v1m2P4_g - Beginner Fat Burning Morning Workout https://youtu.be/1fDHrKRqy34 - How to Lift Dumbbells to Lose Weight (Gym Training) https://youtu.be/70GpsTPeNFs - Burn Back Fat & Bra Bulge (4 Exercises) https://youtu.be/Cljf5O_3vIs - Kickboxing to Lose Flabby Arms / Bingo Wings (No Equipment) https://youtu.be/hDLRNuezpZA - 4-Week Toning Butt & Abs Challenge https://youtu.be/5rReZm8uDM0 - Gentle Morning Yoga Stretches to Feel Energized https://youtu.be/Ib1e_eOFZRo - 30-Minute HIIT Yoga for Slimmer Legs https://youtu.be/MWpNoFdGh4Q - 30-Minute Beginner HIIT Yoga for Stronger Core https://youtu.be/FxJ3VWscT3I - Here's the complete playlist to more than 50 videos: https://www.youtube.com/playlist?list=PLyP8pbBMxcsjSQjf_2V8ZJku_njMfh_Zm
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This is an effective standing abs and thigh workout. Remember to squeeze your muscle while exercising! Let's do this! #nojumpingworkout #allstanding #highintensity Remember everyone stores fat in different areas and there is no study that spot reduction of fat is effective. However this workout increase your fat burn and target your ab and thigh muscles. ❀Full Body Workout ❀Time: 40 sec on/ 10 sec rest Calorie Burn 250 - 350 Cal Warm Up 00:00 - 03:12 Workout 03:12 - 31:33 Cool Down 31:33 - 34:55 *The number of calories you burn will vary from person to person depending on your body composition, workout intensity and also fitness level but this might serve as a guideline. ❀ Don’t forget to Subscribe and turn on notifications so that you don’t miss any Workouts, Community Updates or Surprises: https://www.youtube.com/channel/UC6TSBn2RAx036n04GaN6McA ❀Join the Community: Fitness Channel Instagram: http://instagram.com/eleni.fit__ ❀ My Amazon Storefront: https://www.amazon.de/shop/elenifit ❀ Music: https://www.epidemicsound.com DISCLAIMER If you are new to exercise, you should understand that there is the possibility of physical injury. Please notice that if you performing any exercise or program, you agree that you do so at your own risk. This channel offers health, fitness and nutritional information and is not intended to be a substitute for professional medical advice, diagnosis or treatment.
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Vegetarian people have a lot of problem in taking protein diet. But in today's video you have been told its solution. More information about this is given in the video. ये है कल के 3 वीडियोस 😊 जरूर देखें ! 1.क्या है @Iamjayakishori जी का शादी को लेकर विचार?😱 https://youtube.com/shorts/NVHSjq7VfGc 2.नकली IPL से गुजरातियों ने कैसे उल्लू बनाया😲? https://youtube.com/shorts/RkIPvbIecVo 3.Putin का डरावना फरमान, डरे 🇷🇺 के लोग😨 https://youtube.com/shorts/YfXfM4yBm1s Join us on more Platforms :- ► A2 sir's Instagram https://www.instagram.com/arvind.aroraj/ ► A2 sir's Twitter https://twitter.com/ArorajArvind?s=09 ► A2 Motivation Facebook Page https://www.facebook.com/arvind.aroraj/ ► A2 sir's Linkedin https://www.linkedin.com/in/arvind-aroraj/ ► Conker World Telegram https://t.me/ConkerWorldTelegram ► A2 Motivation Telegram Group https://t.me/a2motivation_official ► Connect With Me On Moj App https://mojapp.in/@a2motivation?referrer=SmB2N9i-1aYFo3j ► This is the "Conker Facebook learning Community" Join now by answering simple questions to win exciting prizes and much more. https://www.facebook.com/groups/conkercommunityy Video Resources :- https://youtu.be/FMytKcuWJNE https://www.youtube.com/watch?v=k67k4te16HY&t=347s&ab_channel=HealthAndFitness https://www.youtube.com/watch?v=RnsYFlP8D7A&t=346s&ab_channel=CWEIndia https://www.youtube.com/watch?v=Y_1C0yuysXM&ab_channel=trickyfoods https://www.youtube.com/watch?v=PN-2spNophY&ab_channel=Maa%2Cyehkaisekarun%3F https://www.youtube.com/watch?v=XugV04NM9q4&ab_channel=SharmisPassions https://www.youtube.com/watch?v=vSJDauIQKDs&ab_channel=VillageCooking-Kerala https://www.youtube.com/watch?v=_UG_FZUDO24&ab_channel=Mr.B-fit. https://www.youtube.com/watch?v=YXF_H3-dPoA&ab_channel=FilterCopy https://www.youtube.com/watch?v=-0ypW07hX_M&ab_channel=AmanGrover Video Credit :- Script by - Satish Bhargav DOP - Akshay kumar Video edited by - Zunaid Siddiqui Thumbnail by - Prathamesh Vaijapurkar SEO by - Hiren Kakadiya Video and channel Managed by - Aqeem Shariff #shorts #youtubeshorts #a2motivation Please Note :- Some of the pics and footages are not real and not related to content and only used for related visualisation purposes only . Pls do not relate these with any real incidents.