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GLP1 + NMDA antagonist?

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Losing fat in 20 days requires a smart and strategic approach. Start with cold therapy, such as cold showers or ice baths, which can activate brown fat and increase metabolism. Incorporate micro workouts—short, intense 5-minute exercise bursts throughout the day—to keep your body in fat-burning mode without long gym sessions. Lastly, follow an early eating window by consuming all your meals within 6-8 hours, promoting better digestion, hormonal balance, and fat loss. These unique methods, combined with a clean diet and proper hydration, can help accelerate results while keeping energy levels high and sustaining long-term progress.

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Semaglutide is a medication that has gained popularity in recent years for its effectiveness in weight loss. It is a glucagon-like peptide-1 (GLP-1) receptor agonist, originally developed for the treatment of type 2 diabetes. However, studies have shown that it can also be used for weight management in individuals with obesity or overweight who have related conditions such as hypertension, dyslipidemia, or type 2 diabetes. The drug has been found to help patients achieve significant weight loss, making it a promising option for those struggling to lose weight through diet and exercise alone.

How Semaglutide Works for Weight Loss

Semaglutide works by mimicking the effects of GLP-1, a hormone that is naturally produced in the body in response to food intake. GLP-1 helps regulate blood sugar levels by stimulating the release of insulin from the pancreas and reducing the production of glucagon, another hormone that raises blood sugar levels. In addition to its effects on blood sugar, GLP-1 also plays a role in appetite regulation and satiety, helping to control food intake and promote weight loss.

When semaglutide is administered, it activates the GLP-1 receptor, leading to similar effects as the naturally occurring hormone. By increasing insulin secretion and reducing glucagon production, semaglutide helps lower blood sugar levels and improve insulin sensitivity. At the same time, it also interacts with the brain to suppress appetite and promote feelings of fullness, leading to reduced food intake and ultimately weight loss.

Furthermore, semaglutide has been shown to slow down the rate at which the stomach empties, which can contribute to a longer-lasting feeling of fullness after meals. This effect, known as delayed gastric emptying, can help individuals consume fewer calories throughout the day and better adhere to a calorie-restricted diet, which is essential for sustainable weight loss.

Potential Side Effects of Semaglutide

While semaglutide can be an effective weight loss treatment, it is not without potential side effects. Like other GLP-1 receptor agonists, semaglutide may cause gastrointestinal symptoms such as nausea, vomiting, diarrhea, or constipation, especially when starting treatment or increasing the dose. These side effects are usually mild to moderate and tend to improve over time as the body adjusts to the medication.

In some cases, semaglutide may also lead to more serious side effects, such as pancreatitis or gallbladder disease. Patients should be monitored closely for signs of these complications, including severe abdominal pain, nausea, or jaundice. Additionally, there have been reports of thyroid tumors in animal studies, although the relevance to humans is not fully understood. It is important for patients to discuss the potential risks and benefits of semaglutide with their healthcare provider before starting treatment.





Other potential side effects of semaglutide include low blood sugar (hypoglycemia), which can occur when the medication is used in combination with other antidiabetic drugs. Patients taking semaglutide should be aware of the symptoms of hypoglycemia, such as dizziness, shakiness, confusion, or sweating, and should monitor their blood sugar levels regularly to prevent complications.

Who Can Benefit from Semaglutide for Weight Loss

Semaglutide may be a suitable option for individuals who have been unsuccessful in previous weight loss attempts and are struggling to achieve and maintain a healthy weight. It is particularly beneficial for those with obesity or overweight who have related metabolic conditions, such as type 2 diabetes, hypertension, or dyslipidemia. Studies have shown that semaglutide can lead to significant weight loss and improvements in metabolic parameters in this population, making it a valuable addition to their treatment regimen.

In addition to its weight loss benefits, semaglutide has also been shown to have positive effects on cardiovascular health, reducing the risk of heart disease and stroke in patients with type 2 diabetes. This makes it a valuable option for individuals with obesity and related conditions who are at an increased risk of cardiovascular complications due to their weight.

However, it is important to note that semaglutide is not a magic bullet for weight loss and should be used in conjunction with a healthy diet and regular exercise to achieve the best results. Patients should work closely with their healthcare provider to develop a comprehensive weight loss plan that includes semaglutide as part of a tailored treatment approach.

Conclusion

In summary, semaglutide is a promising medication for weight loss that works by mimicking the effects of the naturally occurring hormone GLP-1. By reducing appetite, promoting feelings of fullness, and slowing down gastric emptying, semaglutide helps patients consume fewer calories and achieve significant weight loss. While the drug can be effective, it is not without potential side effects, and patients should be monitored closely for adverse reactions. Semaglutide is particularly beneficial for individuals with obesity or overweight who have related metabolic conditions and are struggling to lose weight through diet and exercise alone. By working with their healthcare provider to develop a comprehensive weight loss plan, patients can maximize the benefits of semaglutide and improve their overall health and well-being.

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Carb cutting? No more cheat meals? strength training? Stay tuned to learn about the different ways in which you can burn body fat without the dreadful cardio. Other videos recommended for you: WATCH 🎥: 15 Healthy Benefits Of Doing Yoga For 10 Minutes Every Day - https://www.youtube.com/watch?v=t1Eet94N9KI&list=PL_fl96m7OLQX8Ls3btXcjCcFcxQ2C1djx&index=168 WATCH 🎥: 12 Exercises To Build A Rock Solid Core In 4 Weeks - https://www.youtube.com/watch?v=F0p7u9_oRhY&list=PL_fl96m7OLQX8Ls3btXcjCcFcxQ2C1djx&index=144 #HowToLoseWeight #Cardio #Bestie Sources: https://pastebin.com/94S4Tx1q Timestamps: Intro - 0:00 Say Goodbye to Carbs - 00:47 Stay Active - 01:32 Increase protein intake - 02:08 Cut back on saturated fats - 02:44 Switch Cardio With Strength Training Exercises - 03:30 Sleep Soundly - 04:10 Drink Healthy Beverages - 04:50 Load Up On Fiber - 05:26 Do Yoga - 06:06 Drink Black Coffee - 06:55 Multi Joint Workouts - 07:27 Music: https://www.youtube.com/audiolibrary/music https://www.epidemicsound.com/ Summary: 1. Say Goodbye To Carbs Carb cutting is the first step anyone takes towards their weight loss journey. This means no more high carb foods like rice, bread, starchy vegetables and sweets. When you eat these foods, it turns into fat and gets stored until it is burned out through exercising or physical activities. You can eat them immediately after a heavy workout session to compensate for the lost glucose levels but in small quantities. In short, you have to watch your caloric intake like a hawk. 2. Stay Active This doesn’t mean you have to do squats or push ups any chance you get. It just means that you can do some work around the house or pick up some moderate aerobic exercises. If you have an elevator, take the stairs! If you’ve been sitting down for too long, go out for a brisk stroll. Garden left unattended? Pick up the shovel and get in there! 3. Increase Protein Intake Protein plays a major role in your weight loss journey. A high protein intake will boost metabolism and - most importantly - reduce appetite. Why does this happen? 4. Cut Back On Saturated Fats Also known as unhealthy fats these include animal based products such as meats, starchy vegetables and sugar. These can also be packaged foods like potato chips, pastries, pizza and hamburgers. Did you know that all fats contain 9 calories per gram of fat? That’s more than twice the quantity present in carbs and protein. For more information, please watch the video until the very end. ---------------------------------------------------------------------------------------- Subscribe to Bestie : https://goo.gl/tUqro6 ---------------------------------------------------------------------------------------- Our Social Media: Facebook: https://www.facebook.com/bestieinc/ ---------------------------------------------------------------------------------------- Medical Disclaimer: https://pastebin.com/xLmigD6i Website: www.bestie.com

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While GLP-1 receptor agonists, like Ozempic and Mounjaro, have been a hot topic regarding weight-loss lately, I have seen some concern regarding losing muscle mass (often proxied by lean body mass) when taking these drugs. I cover this topic in this clip from an upcoming research breakdown video where I discuss Lundgren and Colleagues' study, "Healthy Weight Loss Maintenance with Exercise, Liraglutide, or Both Combined," on exercise vs. liraglutide (another GLP-1 receptor agonist) vs. liraglutide + exercise for maintaining weight-loss . Link to study: https://www.nejm.org/doi/full/10.1056/NEJMoa2028198Weight Loss Journey Insights Mounjaro Pcosawareness