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Holly Lofton, MD, an obesity expert at NYU Langone Health, discusses the differences between GLP-1 agonists for weight loss and glycemic control. https://www.medscape.com/viewarticle/995911?src=soc_yt -TRANSCRIPT- I'm Dr Holly Lofton, clinical associate professor of surgery and medicine at NYU Langone Health, and I direct the medical weight management program. My practice is solely based on chronic weight management for adults. Today I'll talk about the various doses of GLP-1 agonists that you may prescribe to your patients. Being that this is based around weight management, I'll start with the weight management medications, the first of which is Saxenda. This is liraglutide 3 mg for chronic weight management. The studies that were done with this medication were intended to get the patient to the 3-mg dosing, which is what's prescribed for weight management, and not the 1.8-mg dosing which is prescribed for type 2 diabetes. However, you may deliver different doses to your patients depending on your goal. You see that this makes a lot of clicking noise. When the patient starts Saxenda and has their pen, there will be this clear fluid. It's important to remind them that this is a multiuse pen and that they should use it over and over again until it's empty. This medication has various doses in the same pen. You want to increase weekly as long as the patient is tolerating it. And by that, I mean not having significant side effects such as nausea, constipation, or other stool changes. When a patient receives the pen, it will start with 0. In the first week, we do 0.6 mg daily. The next week we do 1.2 mg daily. The third week we do 1.8 mg daily. The next week we do 2.4 mg daily, and then the goal is to get the patient to 3 mg, which is the maintenance dose. Ideally, the patient would stay there for their chronic weight management. However, if a patient can't tolerate the dose, you can also have them go to a lower dose for 7 more days and try again. Wegovy, which is semaglutide 2.4 mg, is also prescribed for chronic weight management. This is a single-use cartridge, so the pen will deliver only the dose that you prescribe to the patient. This as well is intended to increase monthly as long as the patient is tolerating it and not having too many significant GI side effects such as nausea, constipation, or loose stool. With this pen, the doses are 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, and 2.4 mg. You increase it monthly or every 4 weeks, depending on the patient tolerance. However, if a patient is not able to tolerate the highest dose, you can prescribe the maximally tolerated dose for that patient. The next new GLP-1 I'll talk about is Ozempic [semaglutide] prescribed for type 2 diabetes. The goals of titrating this medication really depend more on your patient's glycemic control, as this is used for glycemic management. Here we have the red labels and big pen, and this delivers either 0.25 mg or 0.5 mg. The recommendation for this medication is to use 0.25 mg for 4 weeks. Assess the patient's glycemic control, and if needed, increase to 0.5 mg after 4 weeks. Again, this pen delivers either 0.25 mg or 0.5 mg only. This blue-green–label Ozempic [semaglutide] delivers 1-mg dosing, so when your patient turns this one all the way to the end, the only number they will see will be 1. If your patient does not have optimal glycemic control with the lower doses, a 1-mg pen can be prescribed and the patient can continue on that, optimizing their glucose, or you can increase to a 2-mg pen [yellow label], which delivers only 2 mg. This is a single-use cartridge for Trulicity [dulaglutide]. The various doses of Trulicity are 0.75 mg, 1.5 mg, 3 mg, and 4.5 mg. This pen will deliver only the dose that's prescribed, and you can titrate up to optimize glycemic control for your patient. The higher the dose, the better the improvement in glucose and hemoglobin A1c. This is the pen for Mounjaro, which is tirzepatide. At the time of this recording, this medication is intended for type 2 diabetes management. It's a single-use cartridge, and the different doses vary from 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, to the highest dose, 15 mg. Again, this should be titrated to optimize glycemic control for your patient, and you can increase or decrease the dose based on the patient's tolerance. https://www.medscape.com/viewarticle/995911?src=soc_yt

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Dr. Ian Smith shares that he needs this wakeup call because there is science behind drinking water. On the plan, Dr. Ian suggests drinking 1 8-ounce glass of water with a half-squeezed lemon first thing in the morning when you wake up. Lemons can help break down your food, are loaded with vitamin C and are a powerful antioxidant. Plus, lemons can help reduce inflammation. Like us on Facebook: https://www.facebook.com/TheDoctors Follow us on Twitter: https://twitter.com/thedoctors Follow us on Instagram: https://www.instagram.com/thedoctorstv About The Doctors: The Doctors is an Emmy award-winning daytime talk show in its 13th season. The Doctors helps you understand the latest health headlines, delivers exclusive interviews with celebrities dealing with health issues, debates and investigates health and safety claims, explains the latest viral videos and how you can avoid emergency situations, and serves up celebrity chefs to share the hottest and healthiest recipes and foods.

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Welcome to my weekly Semaglutide journey update for Week 2. Let's talk about what's been happening this week, what changed, what went wrong and all the things. I'm also going to answer all your questions from last week in today's update video. Subscribe and turn on notifications for my weekly update videos or follow me on TikTok @haulywoodlife for daily updates. Thanks for being here—enjoy! ----See the daily stuff: tiktok.com/haulywoodlife See you in the next one! Stay Skinny Babes 🫦 , Raphaela ♥ EASY TIMESTAMPS SO YOU CAN FIND WHAT YOU NEED: 00:00 Intro + The Tea 01:10 Three Things I Want To Discuss 03:45 My Semaglutide Dosing Plan 04:30 On The Fence About Minute MD 05:32 Intuitive Eating 07:05 Non Scale Weight Loss Tracking Tools (Renpho Smart Products) 10:18 Final Thoughts From This Week As an Amazon Influencer, I earn from qualifying purchases: https://www.amazon.com/shop/raphaelalaurean ♥ PRODUCTS SHOWN/MENTIONED IN THIS VIDEO: MinuteMD: Semaglutide PrivateLabs: (where I had my original bloodwork done) https://www.privatemdlabs.com?refid=KMivKSNwqg0D (If you use my link, you get a $200 credit towards your next labs) Smart Scale: https://amzn.to/3xghLEr Smart Tape Measure: https://amzn.to/4aBeA8K Smart Food Scale: https://amzn.to/3vu7Pa7 Smart Blood Pressure Monitor: https://amzn.to/3VI8P51 Glucometer: (Blood Glucose Testing Kit): https://amzn.to/4aoCggJ Alcohol Pads: https://amzn.to/3PupTrd Extra Testing Strips: https://amzn.to/3Vvj5O9 Electrolytes: https://amzn.to/49akqNc BCAA's: https://amzn.to/4cqam5I Hand Frother: https://amzn.to/3TxtjdU OR Shop All Of My Semaglutide Weight Loss Journey Faves Here: https://amzn.to/3TL2ILZ ♥MY AMAZON STOREFRONT: https://www.amazon.com/shop/raphaelalaurean ♥ CONNECT ONLINE: https://www.linktr.ee/haulywood ♥ AFFILIATE MARKETING DISCLAIMER: This video and description contain affiliate links, which means that if you click on one of the product links, my channel may receive a small commission to help purchase more products to do reviews. As an Amazon Associate, I earn from qualifying purchases. My family and I appreciate you. Thank you. ♥ SUBSCRIBE FOR MORE: Subscribe Here: https://www.youtube.com/@haulywood?sub_confirmation=1 Thanks for watching and commenting. See you in the next one. Stay Skinny Babes 🫦 ! ♥ WANT TO WORK TOGETHER ON A SPONSORED VIDEO? Send Collab Requests To: [email protected] Have A Look Around: https://www.raphaelalaurean.com ♥ SEARCH TERMS: #semaglutide #weightlossjourney #renpho @RENPHO @minutemd

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In the cynical landscape of diets, the pundits say that sustainable long term weight loss is impossible. Follow Tony Vassallo, a former morbidly obese survivor, and 15 others considered ‘one percenters', to defy the odds and explore the question of, is it possible to lose the weight and keep it off? Be Sure to LIKE & SUBSCRIBE. Website: https://www.followmefilm.ca/index.html Facebook: https://www.facebook.com/FollowMeFilm.ca Instagram: https://www.instagram.com/followmedoc/ Highlights & Images From Hot Docs Premiere & Windsor International Film Festival: https://www.modaformen.ca/documentary MODA For Men Weight Loss: https://www.modaformen.ca/ MODA Nutrition & Weight Loss: https://www.modaweightloss.ca/ The Origins of Follow Me Tony Vassallo spent the better part of 30 years being morbidly obese. His top weight was just over 300 pounds which occurred when he was 37 years of age. After losing 130 pounds in 2010 he wondered if he would be just another statistic who would regain the weight? Determined to keep the weight off, Tony embarked on a journey to learn everything he could about weight loss, nutrition and food addiction. This yearning to learn more allowed Tony to leave a 15 year career in information technology to pursue a career helping others towards sustained weight loss. In May of 2016, The New York Times published a story “After The Biggest Loser,’ Their Bodies Fought to Regain Weight” which received a great deal of attention. Tony was deeply frustrated by the story for many reasons. He felt the story implied that weight loss is impossible and therefore a waste of time, while Tony knew from his own experiences that it could be done. Around the same time, a client of Tony’s and co-producer of the film, Jason Donville also became fascinated with the idea that a small segment of the population appeared to have succeeded with permanent weight loss. What is it about this group of that allowed them to succeed in losing their excess weight and keeping it off? Tony knew there were many others who had achieved what he had achieved and he had his own theories based on his own personal experience as to why they had succeeded. But Tony had met very few of them in person. Thus, the film “Follow Me” is Tony’s journey to meet, listen to and understand others who have succeeded at sustained weight loss. The objective of the film is therefore to allow others that struggle with weight and related illnesses tied to obesity to hear various points of view from those that lived a similar experience. The film is also about hope. The journey “Follow Me” had producer Tony Vassallo meet 15 diverse people from across Canada and the United States. The 15 included medical doctors, students, business professionals, writers, tradesmen, a university professor, a counsellor, a culinary professional, and even a psychotherapist. Tony was accompanied on his journey by first time Film Director Nicholas Li, who does an extraordinary job of capturing the visual beauty of the places Tony visited on the journey while also amalgamating all these incredible messages of hope into an entertaining and thought provoking look at sustained weight loss. Website: https://www.followmefilm.ca/index.html Highlights & Images: https://www.modaformen.ca/documentary Instagram: https://www.instagram.com/followmedoc/ Contact: Producer: [email protected] Director: [email protected]

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