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Metformin is an oral medication commonly used to manage type 2 diabetes mellitus. It is often the first-line treatment due to its effectiveness, safety profile, and additional benefits beyond blood sugar control. Mechanism of Action Metformin primarily works by: Reducing Hepatic Glucose Production**: It decreases the amount of glucose produced by the liver, particularly by inhibiting gluconeogenesis (the process of generating glucose from non-carbohydrate sources). Increasing Insulin Sensitivity**: Metformin enhances the sensitivity of peripheral tissues (like muscle and fat) to insulin, facilitating better uptake of glucose from the bloodstream. Decreasing Intestinal Absorption of Glucose**: It may also reduce the absorption of glucose from the gastrointestinal tract. Indications Metformin is indicated for: Type 2 Diabetes Mellitus**: It is used to improve glycemic control in adults and children (larger than & equal to 10 years), typically in conjunction with diet and exercise. Polycystic Ovary Syndrome (PCOS)**: Off-label, it is sometimes used to manage symptoms related to insulin resistance in women with PCOS. Dosage and Administration Formulations**: Metformin is available in immediate-release and extended-release formulations. Dosing**: The initial dose is usually low, gradually increased based on tolerance and glycemic control. The maximum dose typically does not exceed 2,000-2,500 mg per day, depending on the formulation. Side Effects Common side effects include: Gastrointestinal issues: Nausea, vomiting, diarrhea, abdominal discomfort, and flatulence (often transient). Lactic acidosis: A rare but serious side effect, particularly in individuals with renal impairment or contraindicating conditions. Contraindications Metformin is contraindicated in: Severe renal impairment (eGFR less than 30 mL/min) Acute or chronic metabolic acidosis, including diabetic ketoacidosis Hypersensitivity to metformin Cautions Renal Function Monitoring**: Kidney function should be assessed before starting therapy and regularly monitored during treatment. Use in Specific Populations**: Caution is advised in patients with liver disease, heart failure, or those undergoing procedures involving contrast media, as these can increase the risk of lactic acidosis. Benefits Beyond Glycemic Control Metformin has additional benefits, including: Weight Management** It is generally weight-neutral or may even promote modest weight loss, making it suitable for overweight individuals with type 2 diabetes. Cardiovascular Benefits**: Some studies suggest that metformin may have cardiovascular protective effects. Conclusion Metformin is a cornerstone in the management of type 2 diabetes, known for its efficacy in lowering blood sugar levels, safety profile, and additional health benefits. As with any medication, it should be prescribed and monitored by a healthcare professional, ensuring that patients receive the most appropriate and effective treatment for their condition. Regular follow-up and lifestyle modifications (diet and exercise) are essential components of diabetes management alongside metformin therapy.

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¿Qué pasa si tomas altas dosis de Vitamina D3? LA TIENDA DEL DR. BERG:https://shop.drberg.com/ Dr. Eric Berg DC Bio: Dr. Berg, es un quiropráctico especializado en cetogénesis saludable y ayuno intermitente. Es autor del best seller The Healthy Keto Plan (El plan Keto saludable) Es también el director de Dr. Berg Nutritionals. En estos momentos no ejerce como médico, sino que se dedica a educar al público sobre temas de salud a través de las redes sociales. Descargo de responsabilidad. El Dr. Eric Berg recibió su título de Doctor en Quiropráctica del Palmer College of Chiropractic en 1988. El uso de la palabra “doctor” o la abreviación Dr. asociado a su nombre se refiere solamente a ese título. El Dr. Berg ostenta licencias de quiropráctica en los estados de Virginia, California y Luisiana, y aunque mantiene su licencia en activo, no ejerce como quiropráctico en ningún estado y no atiende a pacientes. Educar al público es ahora su ocupación a tiempo completo. Este video se presenta solamente a título informativo. No debe usarse para auto diagnosticarse y no sustituye ni puede sustituir a un examen médico. No debe usarse como curación, tratamiento, diagnóstico, receta o recomendación. Este video tampoco establece un vínculo entre doctor y paciente entre el Dr. Berg y usted. No debe hacer ningún cambio en su régimen alimenticio o dieta sin antes consultar con un médico y pasar un examen médico, diagnóstico y recomendación. Busque siempre el consejo de un médico o cualquier profesional de la salud y dirija sus preguntas sobre enfermedades a dicho profesional. The Health & Wellness, Dr. Berg Nutritionals y Dr. Eric Berg, D.C. no se hacen responsables ni están sujetos a ninguna responsabilidad civil por cualquier consejo, tratamiento o diagnóstico o cualquier otra información, servicio o producto que obtenga a través de este video o página web. #Keto #DietaCetogenica #BajarDePeso #Salud #DrBergEnEspañol #comersano

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If you just can’t find time during the day to exercise, this bedtime workout will help you stay fit, flexible, and fabulous! You’ll go to bed feeling refreshed, you’ll sleep better, and your muscles will be nice and relaxed by morning. Watch our new video to follow along with this low-impact workout. It’s quick and easy, there’s no equipment needed, and you can squeeze it in before sleep. Whether you’re an early riser and the first thing you do is head to the gym or you prefer to exercise after you have some food in your system, people who exercise enjoy better sleep than those who don’t. According to the National Sleep Foundation, people who exercise lightly see a 49% increase in quality of sleep. TIMESTAMPS: Warm-up 0:41 Squats 2:20 Donkey kicks 3:42 Push-ups 5:05 Squat and side crunch 6:25 Plank-ups 7:52 Standing crossover toe touches 9:11 Cool down 1:32 #sleepbetter #homeworkout #insomnia Music by Epidemic Sound https://www.epidemicsound.com/ SUMMARY: - #1. To make sure you’re bringing your knee high enough, you can bend your elbows at a 90º angle and touch your knee to your hand. To make this move harder, add a slight jump to the exercise while you bring your knees up high. - #2. If you have a hard time balancing, extend your arms as you head down, and lower them while you stand. If that’s too difficult, you can place a chair behind you to balance yourself. - #3. Avoid using momentum and letting your leg drop back down as you’ll be missing out on the workout if you do. Keep the movement controlled. - #4. For an easier approach, you can modify the exercise by letting your knees rest on the floor. - #5. This move will target your abdominals and work on your oblique muscles. It’s a great exercise to get rid of love handles. - #6. This is a killer move that will strengthen your core, and it will also tone up your arms, shoulders, glutes, and abdominals. If this is too intense, try holding an elbow plank position: hold yourself up by your forearms for as long as you can. - #7. This move involves your lower back and targets your abdominals and obliques. It will improve your flexibility and strength. - #8. Doing this cool down will ensure that your muscles are nice and loose for when you get up in the morning. Subscribe to Bright Side : https://goo.gl/rQTJZz ---------------------------------------------------------------------------------------- Our Social Media: Facebook: https://www.facebook.com/brightside/ Instagram: https://www.instagram.com/brightgram/ 5-Minute Crafts Youtube: https://www.goo.gl/8JVmuC ---------------------------------------------------------------------------------------- For more videos and articles visit: http://www.brightside.me/

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