GLP-1 is secreted by intestinal cells in response to glucose ingestion and acts on the vagus nerve and hypothalamus to induce satiety. Subscribe to Nourishable at https://www.youtube.com/c/Nourishable
This video is part 6 of the Neurobiology of Food Intake module within a lecture series on the nutrition science of macronutrients.
Neurobiology of Food Intake Lecture playlist: https://youtube.com/playlist?list=PLK6oS2Cd-6PE_gAHJP2eQaP01IrvL7OQJ
Macronutrients Lecture playlist: https://youtube.com/playlist?list=PLK6oS2Cd-6PGI0ALaBRBb10s51Z0NEmvw
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Video Production by Robbie Hyde
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The information in this video is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images and information, contained on or available through this video is for general information purposes only.
References
Klockars, A. et al. Hypothalamic Integration of the Endocrine Signaling Related to Food Intake. Curr. Topics Behav. Neurosci. (2019) 43:239-270
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Glucagon-like peptide 1, or GLP-1, is a hormone secrets by the L cells in the intestine in response to glucose ingestion in proportion to consumed calories. GLP-1 stimulates insulin secretion from the pancreas to prepare the body for high blood glucose levels - this makes it an incretin because it increases insulin. Further, GLP-1 inhibits glucagon. GLP-1 binds to chemoreceptors on the vagus nerve to activate the vagus to send afferent signals to stimulate the nucleus tractus solitarius in the hindbrain to stimulate satiety. GLP slows gastric emptying which keeps the GI tract stretched and distended for longer - this activates the stretch-sensitive mechanoreceptors on the vagus to additionally stimulate the NTS. GLP-1 crosses the blood-brain-barrier of the hypothalamus to activate the POMC neurons in the arcuate nucleus. POMC neuron stimulation causes release of the neurotransmitter alpha MSH which stimulates the paraventricular hypothalamus to induce satiety. GLP-1 also inhibits the orexigenic AgRP neurons. GLP-1 is an anorexigenic, satiety-inducing hormone.
Yoga And Weight Loss 4
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Dr. Johann Mañez talks about the health advantages of plant-based diet, particularly in preventing the development of type 2 diabetes and heart problem.
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The Glp1 Revolution A Weight Loss Journey Update
Struggling with keto flu, low energy, or digestion issues on the ketogenic diet? You’re not alone! In this video, I’ll break down the **4 essential supplements experts recommend** to optimize your keto journey, avoid nutrient deficiencies, and stay in fat-burning mode.
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I’ll also share **pro tips on dosage, best brands, and how to incorporate these supplements** for maximum results. Whether you're new to keto or a seasoned pro, these must-have supplements can make a HUGE difference!
📌 **TIMESTAMPS:**
– Intro: Why You Need Supplements on Keto
– #1 Electrolytes (Avoid Keto Flu!)
– #2 MCT Oil (Energy & Ketosis Hack)
– #3 Omega-3s (Critical for Inflammation)
– #4 Digestive Enzymes (Better Digestion)
– Bonus: My Personal Supplement Routine
– Final Tips & Mistakes to Avoid
💡 **Want a FREE keto meal plan?** Download my **7-Day Keto Reset Guide** here: [Insert Link]
💬 **Did I miss any supplements you love?** Let me know in the comments!**
👍 **If this helped you, smash the LIKE button and SUBSCRIBE for more keto & health tips!**
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### **Why These Supplements Matter:**
The keto diet is amazing for fat loss and mental clarity, but it can also deplete key nutrients. Without the right supplements, you might experience fatigue, muscle cramps, poor digestion, or stalled progress. Experts agree—these four supplements are **non-negotiable** for long-term keto success!
🔔 **Turn on notifications** so you don’t miss my next video on **"5 Keto Mistakes That Slow Fat Loss"**!
72 Pounds Down My Glp 1 Weight Loss Journey
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Taking a GLP-1 like Ozempic, Wegovy, Mounjaro or Zepbound? Staying on track just got SO much easier! 👋
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