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Watch the full interview with Dr. Boz on YouTube 👉 https://youtu.be/zAe5MB1Qtdo Dr. Annette Bosworth (Dr. Boz) is an internal medicine physician, author and educator. She’s and expert in metabolic and brain health. Subscribe to The Ultimate Health Podcast on YouTube: https://www.youtube.com/@JesseChappus (And be sure to hit the 🔔 to get notified when new videos are released!) Show notes: https://ultimatehealthpodcast.com/637 Listen & subscribe to The Ultimate Health Podcast ✩ Apple Podcasts: https://bit.ly/tuhpapple ✩ Spotify: https://bit.ly/tuhpspotify Connect with The Ultimate Health Podcast ✩ Website: https://ultimatehealthpodcast.com ✩ Instagram: https://www.instagram.com/ultimatehealthpodcast #drboz #jessechappus #keto About the Podcast Jesse Chappus has in-depth conversations with health and wellness leaders from around the world. Topics include lifestyle, nutrition, fitness, self-help, sleep, meditation, spirituality and so much more. Tune in weekly to take your health to the next level!

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Inhibitors of dipeptidyl peptidase 4 (DPP-4 inhibitors or gliptins) are a class of oral hypoglycemics that block the enzyme dipeptidyl peptidase-4 (DPP-4). They can be used to treat diabetes mellitus type 2. The first agent of the class – sitagliptin – was approved by the FDA in 2006.[1] Glucagon increases blood glucose levels, and DPP-4 inhibitors reduce glucagon and blood glucose levels. The mechanism of DPP-4 inhibitors is to increase incretin levels (GLP-1 and GIP),[2][3][4] which inhibit glucagon release, which in turn increases insulin secretion, decreases gastric emptying, and decreases blood glucose levels. A 2018 meta-analysis found no favorable effect of DPP-4 inhibitors on all-cause mortality, cardiovascular mortality, myocardial infarction or stroke in patients with type 2 diabetes.[5] ExamplesEdit Drugs belonging to this class are: Sitagliptin[6] (FDA approved 2006, marketed by Merck & Co. as Januvia) Vildagliptin[7] (EU approved 2007, marketed in the EU by Novartis as Galvus) Saxagliptin (FDA approved in 2009, marketed as Onglyza) Linagliptin (FDA approved in 2011, marketed as Tradjenta by Eli Lilly and Company and Boehringer Ingelheim)[8] Gemigliptin (approved in Korea in 2012, marketed by LG Life Sciences)[9] Marketed as Zemiglo Anagliptin (approved in Japan in 2012, marketed by Sanwa Kagaku Kenkyusho Co., Ltd. and Kowa Company, Ltd.)[10] Teneligliptin (approved in Japan in 2012[11]) Alogliptin (FDA approved 2013, marketed by Takeda Pharmaceutical Company) Trelagliptin (approved for use in Japan in 2015) Omarigliptin (MK-3102) (approved in Japan in 2015,[12] developed by Merck & Co.; research showed that omarigliptin can be used as once-weekly treatment and generally well-tolerated throughout the base and extension studies[13]) Evogliptin (approved for use in South Korea[14]) Gosogliptin (approved for use in Russia[15]) Dutogliptin (being developed by Phenomix Corporation), Phase III[16] Other chemicals which may inhibit DPP-4 include: Berberine, an alkaloid found in plants of the genus Berberis, inhibits dipeptidyl peptidase-4 which may at least partly explains its antihyperglycemic activity.[17] Adverse effectsEdit In those taking sulphonylureas, there is an increased risk of low blood sugar.[18] Adverse effects, including nasopharyngitis, headache, nausea, heart failure, hypersensitivity and skin reactions. The U.S. Food and Drug Administration (FDA) is warning that the type 2 diabetes medicines like sitagliptin, saxagliptin, linagliptin, and alogliptin may cause joint pain that can be severe and disabling. FDA has added a new Warning and Precaution about this risk to the labels of all medicines in this drug class, called dipeptidyl peptidase-4 (DPP-4) inhibitors.[19] However, studies assessing risk of rheumatoid arthritis among DPP-4 inhibitor users have been inconclusive.[20] A 2014 review found increased risk of heart failure with saxagliptin and alogliptin, prompting the FDA in 2016 to add warnings to the relevant drug labels.[21] A 2018 meta analysis showed that use of DPP-4 inhibitors was associated with a 58% increased risk of developing acute pancreatitis compared with placebo or no treatment.[22] A 2018 observational study suggested an elevated risk of developing inflammatory bowel disease (specifically, ulcerative colitis), reaching a peak after three to four years of use and decreasing after more than four years of use.[23] CancerEdit In response to a report of precancerous changes in the pancreases of rats and organ donors treated with the DPP-4 inhibitor sitagliptin,[24][25] the United States FDA and the European Medicines Agency each undertook independent reviews of all clinical and preclinical data related to the possible association of DPP-4 inhibitors with pancreatic cancer. In a joint letter to the New England Journal of Medicine, the agencies stated that they had not yet reached a final conclusion regarding a possible causative relationship.[26] A 2014 meta-analysis found no evidence for increased pancreatic cancer risk in people treated with DPP-4 inhibitors, but owing to the modest amount of data available, was not able to completely exclude possible risk.[27] Combination drugsEdit Some of the DPP-4 inhibitor drugs have gotten approval from the FDA to be used with metformin concomitantly with additive effect to increase the level of glucagon-like peptide 1 (GLP-1) which also decreases hepatic glucose production.[28]

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đŸ”„ Want to lose fat and stay on track? Start your day with a high-protein breakfast! đŸ”„ Here’s why it works: 👇 ✔ Keeps you full longer – Protein takes longer to digest, reducing hunger throughout the day. ✔ Stops junk food cravings – Less hunger means fewer temptations to grab unhealthy snacks. ✔ Boosts metabolism – Protein requires more energy to digest, helping you burn more calories. ✔ Supports muscle health – Protein keeps your muscles strong while losing fat. A high-protein breakfast like eggs, Greek yogurt, or a protein smoothie can set you up for success all day. đŸ„šđŸł Ready to fuel your goals? Comment 👉 “FREE” below to get tips on building a sustainable fat-loss plan that works for YOU! đ——đ—¶đ˜€đ—°đ—čđ—źđ—¶đ—șđ—Č𝗿: This information is for educational purposes only. It is not a substitute for medical care.

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Dive into the delightful world of the keto diet with our video, "Fun Facts About the Keto Diet You Didn't Know!" Join us for a lively exploration filled with surprising tidbits and humorous insights that will keep you entertained while learning about this popular low-carb lifestyle. Discover why bacon is practically a food group, the science behind ketosis, and how the keto craze has transformed the way we eat! Perfect for both keto newbies and seasoned dieters, this fun-filled ride will change the way you view carbs forever. Don't forget to like and share this video with friends who need a laugh! #KetoDiet #FunFacts #LowCarb #HealthyEating #NutritionHumor OUTLINE: 00:00:00 Welcome to John on Keto 00:00:36 From Hospital to Hollywood 00:01:55 Bacon and Cheese? Yes, Please! 00:02:27 Unleash Your Inner Genius 00:03:05 The Ultimate Showdown 00:04:37 The Dynamic Duo 00:05:49 The Good Cholesterol Champion 00:06:22 A Heart-Healthy Diet? You Butter Believe It! 00:06:56 Your Ticket to a Healthier, Happier You!

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My 12-week recap of how I lost 15 lbs of fat while UPPING my milk supply 6 - 9 months postpartum! Comment ME if any of this hit home for you ❀ And if you want to see exactly what l am doing and how I’m making this work without crazy restrictions-hit that follow button. I’ve got you, mama. đŸ«¶đŸŒđŸ’›đŸ’ȘđŸŒ Check out my bio for more info on my natural GLP1 Activator or comment below! #allnatural #naturalwellness #naturalwellnessmama #glp1 #glp1weightloss #postpartum #postpartumjourney #postpartumweightloss #beforeandafter

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Belly Fat Burning Exercises for Women || Exercises to Lose Belly Fat#bellyfat #shorts #motivation Nutrivitamins and Digital Products 👉 https://sites.google.com/view/nutrivitamins Join this channel to get access to perks: https://www.youtube.com/channel/UC07RM2unzo1u5x2nK3xgC7w/join To Stay Fit and Healthy PLS Subscribe 👇 https://www.youtube.com/@fitnessmantram Read More on Health and Fitness 👉 https://fitnessmantram.com/ General Disclaimer: The information provided on this channel is for educational and entertainment purposes only and should not be construed as medical advice. Always consult with a qualified healthcare professional before starting any new fitness program, especially if you have any underlying health conditions. Specific Disclaimers: Results may vary: The results shown on this channel are not guaranteed and may vary depending on individual factors such as genetics, health, lifestyle, and diet. Exercise caution: The exercises demonstrated on this channel may not be suitable for everyone. Be sure to listen to your body and modify exercises as needed. Professional advice: The information provided on this channel is not a substitute for professional advice from a qualified fitness instructor or therapist. Product and service endorsements: Any products or services mentioned on this channel are not necessarily endorsed by Fitnessmantram. Affiliate links: This channel may contain affiliate links to products or services. If you click on an affiliate link and make a purchase, Fitnessmantram may receive a commission. Errors and omissions: The information provided on this channel may contain errors or omissions. Fitnessmantram does not accept responsibility for any harm or loss resulting from the use of this information. Note : Some of the pictures used in this video belongs to the real owners. We don't have any authority / right on the pictures used. This Channel contains affiliate links. If you choose to make a purchase after clicking a link the author/owner/creator may receive a commission at no ADDITIONAL cost to you. Thank you for your support! This Channel doesn't promote or encourage any illegal activities, all contents provided by This channel is meant for EDUCATIONAL PURPOSE under fair use. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. If you are pregnant, nursing, taking medication, or have a medical condition, consult your physician before using any products. An AI created reaction image is shown in video. Copyright Disclaimer: Under Section 107 of the Copyright Act 1976, allowance is made for 'Fair Use' for purposes such as criticism, comment, news reporting, teaching, scholarship, and research, Fair use is a permitted by copyright statute that might otherwise be infringing, Non-profit, educational or personal use tips the balance in favor of fair use.

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A video showcasing the preparation of a ketogenic dietary supplement drink. The content creator opens a yellow packet labeled "NAT Pure Therapeutic Ketones Splash," pours the powder into a red water bottle with liquid, adds water, and shakes it. The video ends with them drinking the prepared supplement drink.#ketodrink #ketosupplement #healthylifestyle #ketodiet #wellnessjourney

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