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Oncotarget published this trending research paper on February 2, 2021, entitled, "Testosterone deficiency in men receiving immunotherapy for malignant melanoma" by researchers from the University of Iowa.
Abstract:
Immunotherapy has been established as a standard of care for patients with malignant melanoma, however, the long-term side-effects of immunotherapy are still emerging. Studies over the last decade have documented increasing reports of endocrine dysfunction following the initiation of immunotherapy. Our study aimed to detect the proportion of men who have low testosterone before, during, and or/after receiving immunotherapy for malignant melanoma, and to determine the proportion of men who receive testosterone replacement therapy after detection of low testosterone. We performed retrospective chart review of patients with malignant melanoma treated with immunotherapy. Low testosterone was identified in 34 out of 49 patients at some point during their treatment with immunotherapy. Despite low testosterone levels in two-thirds of patients, only three patients were treated with testosterone replacement therapy. In addition to laboratory evidence of low testosterone, patients were also symptomatic as 43 out of 49 patients reported fatigue to their providers. Four patients developed hypophysitis and subsequent hypopituitarism, all of whom were receiving Ipilimumab. We conclude that patients with stage 3 or 4 melanoma treated with immunotherapy appear to be at an increased risk of developing testosterone deficiency during their treatment.
Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.27876
DOI - https://doi.org/10.18632/oncotarget.27876
Full text - https://www.oncotarget.com/article/27876/text/
Correspondence to - Madeline Peters - [email protected]
Keywords - cancer, melanoma, immunotherapy, testosterone deficiency, androgens, skin cancer
About Oncotarget
Oncotarget is a bi-weekly, peer-reviewed, open access biomedical journal covering research on all aspects of oncology.
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This All-In-One Formula Will Skyrocket Your Testosterone: 👉 https://drsam.co/s/yt/TestosteroneGrowth 3 Most Popular Videos About Testosterone & Sex Drive: 👉 https://www.youtube.com/watch?v=AbNyVIqZ36s 👉 https://www.youtube.com/watch?v=NZNElbAP9_E 👉 https://www.youtube.com/watch?v=-8DB5nkzBc4 = How Do 𝐒𝐪𝐮𝐚𝐭𝐬 𝐈𝐧𝐜𝐫𝐞𝐚𝐬𝐞 𝐓𝐞𝐬𝐭𝐨𝐬𝐭𝐞𝐫𝐨𝐧𝐞? = ============== Thank you for watching. Please feel free to comment, like or share with your friends. Visit Dr.Sam Robbins's blog for more information on your health! http://www.drsamrobbins.com/ =============== Thanks DrSamRobbins Disclaimer: As with all information, products and services, results are not guaranteed and may vary from one individual to another. The information in this video and/or at this channel is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge, educational and information from the research and experience of Dr. Sam Robbins, who encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional. Statements made, or solutions suggested in this video and/or at this channel, have not been evaluated by the Food and Drug Administration. They are not intended to diagnose, treat, cure, or prevent any disease.
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