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Tadalafil and sildenafil are both medications used to treat erectile dysfunction (ED), but they have different characteristics, mechanisms of action, and usage guidelines. Here is a detailed comparison of the two: Mechanism of Action Tadalafil: Inhibits phosphodiesterase type 5 (PDE5), which increases cyclic guanosine monophosphate (cGMP) levels. This results in smooth muscle relaxation and increased blood flow to the penis. Tadalafil also has a mild effect on PDE11. Sildenafil: Also inhibits PDE5, leading to increased cGMP levels and improved blood flow to the penis. It primarily affects PDE5. Duration of Action Tadalafil: Known for its longer duration of action, it can remain effective for up to 36 hours, earning it the nickname "the weekend pill." Sildenafil: Typically effective for 4-6 hours. Onset of Action Tadalafil: Generally starts working within 30 minutes to 2 hours after ingestion. Sildenafil: Usually takes effect within 30-60 minutes. Dosing Tadalafil: Can be taken as needed (10-20 mg) or once daily in a lower dose (2.5-5 mg) for those who anticipate frequent sexual activity. Sildenafil: Typically taken as needed, in doses of 25, 50, or 100 mg. Food Interactions Tadalafil: Can be taken with or without food, and its absorption is not significantly affected by food. Sildenafil: Absorption can be delayed and reduced by high-fat meals, potentially decreasing its effectiveness. Side Effects Tadalafil: Common side effects include headache, dyspepsia (indigestion), back pain, muscle aches, nasal congestion, flushing, and limb pain. Muscle aches and back pain are more unique to tadalafil. Sildenafil: Common side effects include headache, flushing, dyspepsia, nasal congestion, and visual disturbances (such as a blue tint to vision). Contraindications and Interactions Tadalafil: Should not be taken with nitrates or alpha-blockers, as it can cause significant drops in blood pressure. Caution is advised with other medications that affect blood pressure. Sildenafil: Also contraindicated with nitrates and certain alpha-blockers for the same reason. It can interact with various other medications, including some antifungals and antibiotics. Special Considerations Tadalafil: Often preferred for its longer duration, allowing more spontaneity. It’s also approved for treating benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension under different brand names and dosages. Sildenafil: Sometimes preferred for its shorter duration, which may be suitable for men who do not want the effects to last as long. It’s also used to treat pulmonary arterial hypertension under a different brand name. Cost and Availability Both medications are available as generic versions, which are typically less expensive than the brand names (Cialis for tadalafil and Viagra for sildenafil). Effectiveness Both drugs are similarly effective for most men with ED, though individual response can vary. Some may respond better to one medication over the other. In summary, the choice between tadalafil and sildenafil often comes down to personal preference, lifestyle, and specific medical needs. Tadalafil’s longer duration may offer more flexibility, while sildenafil’s shorter duration may be preferable for others. Always consult with a healthcare provider to determine the best treatment option based on individual health conditions and needs. Thank you for subscribing and enjoy watching 😎 Please support this channel by hitting the like and subscribe buttons, and ring the bell to get updates!! Disclaimer: This is Non-Commercial and educational entertainment channel 🏡💪👆
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Men with BPH may not experience any symptoms at all but men who have symptoms may experience urinary hesitancy, straining or pushing to urinate, weak urine stream, discomfort with urination, urinary urgency and frequency, urinary tract infections, waking up to use the bathroom more than twice, urinary incontinence, post-void dribbling, reduced urinary flow, and feelings of not fully emptying the bladder.
BPH can affect sex and intimacy too. Although not a direct cause, certain medications and surgical treatments for BPH may contribute to erectile difficulty and ejaculatory issues like retrograde ejaculation and discomfort with ejaculation. Physical changes in the prostate may also be a reason but there has been no clear correlation between the size of the prostate gland and symptom severity.
If you're experiencing bothersome symptoms of BPH, schedule your appointment today https://drsusieg.com/
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► THE BODY TRANSFORMATION BLUEPRINT Science-based muscle building and fat loss system: http://www.BodyTransformationTruth.com ► REALSCIENCE ATHLETICS No B.S, premium quality supplements you can trust: http://www.RealScienceAthletics.com CONNECT WITH ME Blog: http://www.SeanNal.com Instagram: https://www.instagram.com/Sean_Nalewanyj/ Facebook: https://www.facebook.com/SeanNalewanyjOfficial GET YOUR FREE CUSTOM MEAL PLAN http://www.SeanNal.com/free-meal-plan.php TAKE MY ONLINE FITNESS QUIZ http://www.SeanNal.com/quiz-questions.php -------------------------------------------------------------------------------- Testosterone Optimizing Vitamins/Minerals: https://www.youtube.com/watch?v=UPE40qRq8C0 -------------------------------------------------------------------------------- Video Transcript Q&A: "Foods That Boost Testosterone Levels?" Hey what's up guys, Sean Nalewanyj here with another Muscle In Minutes Q&A where I give quick, to the point answers to your fitness questions. So, today’s question is, what are the best foods out there to eat to naturally boost your testosterone levels. So my advice here is just to recognize the fact that optimizing your natural testosterone levels is really not going to be determined by whether you specifically eat oysters or nuts or avocado, but instead it’s going to be determined by your overall diet and your overall lifestyle as a whole. You’ll find a lot of articles online that list things like “10 super-foods that boost your testosterone” or something along those lines, but really that just sort of misses the big picture. The truth is that there really aren’t any “special” food items out there that are going to magically make a big measurable difference to your testosterone levels on their own, and instead I really would recommend that you just focus on the more basic, overall factors. Make sure that you’re getting enough fat in your diet, this is a really important one, so somewhere between 20-30% of your total calories and definitely no lower than 15%. You want to make sure that you’re getting enough protein so somewhere around 1 gram per pound of body weight daily. That you’re getting a good restful sleep each night. That you’re training intensely in the gym on a consistent basis. That you’re managing stress levels effectively. And that you’re getting enough of certain vitamins and minerals, specifically vitamin D, zinc and magnesium which is a topic that I addressed in a previous video and I'll link in the description box below. Eating certain food sources might help out simply because they might be higher in fat and protein content which might help to bring your daily totals into the proper range if they’re currently too low, but assuming that your overall macronutrient intake is properly structured at the outset, then going out of your way to consume a higher amount of red meat or egg yolks that's really not going to magically boost your testosterone levels into an above-normal range, and also keep in mind that if your testosterone levels are already within the normal range to begin with, then there’s not a lot you can do aside from actual anabolic steroid use to further raise those levels high enough in order to positively impact muscle growth or gym performance anyway.
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