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Developed and produced by http://www.MechanismsinMedicine.com Animation Description: This animation represents a visual interpretation of the production of testosterone and is not indicative of clinical effectiveness. The hypothalamus releases gonadotropin-releasing hormone (GnRH) in pulses every 60 to 90 minutes to stimulate the pulsatile release of luteinizing hormone (LH) from the pituitary gland into the bloodstream. LH binds the LH receptor on the Leydig cells of the testes. Binding initiates a cascade of events which include the conversion of cholesterol (depicted as LDL here) to pregnenolone followed by a series of reactions, which convert pregnenolone to testosterone. Testosterone, secreted by the testes, diffuses into the peripheral circulation to be carried to target tissues. In liver, muscle and adipose tissue, testosterone binds directly to its androgen receptor (AR) to exert its biological effect. In skin, hair, the prostate gland and gonadal tissue, testosterone must be converted to dihydrotestosterone (DHT) by 5-alpha-reductase in order to bind the androgen receptor. In bone and brain, testosterone is converted by aromatization to estradiol (E2), which binds the estrogen receptor (E2R) to carry out its effects. There is an accompanying accredited online resource, http://www.ManagingTD.ca that contains the learning materials, as well as videos, animations & an interactive algorithm.

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Is high-dose CBD harmful to your liver? In this Cannafyl Podcast, Ed Chaney and Kimberly Rose break down a recent FDA-funded study on liver enzymes and CBD use. In this episode of The CBD Ed Show, Ed Chaney and Kimberly Rose explore a 2023 FDA-funded clinical trial that sparked questions about the safety of high-dose CBD isolate. The study involved 201 healthy adults taking 1,500mg of CBD daily for six weeks. We share expert commentary from Dr. Bonnie Goldstein, who argues the study doesn't reflect real-world CBD use. Learn the differences between CBD isolate vs full-spectrum, understand what elevated liver enzymes really mean, and find out what this study actually says about CBD safety. Timestamps: 00:00 – Introduction to the CBD Study 01:00 – Study Overview & Relevance 02:00 – High-Dose CBD Design 04:00 – Cost of High-Dose CBD 05:30 – What Are Liver Enzymes (ALT & AST)? 07:00 – Study Findings on Liver Health 09:00 – Dr. Goldstein’s Critique 12:00 – Full-Spectrum vs. Isolate 16:00 – Real Consumer Takeaways 20:00 – Final Thoughts on CBD Safety 22:00 – Ask Us Your Questions! Listen to more episodes: https://thecbdedshow.org Shop premium CBD: https://cannafyl.com CBD Sleep Box for Hotels: https://cannafyl.com/pages/sleep Disclaimer: CBD is not intended to diagnose, treat, cure, or prevent any disease.

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It is crucial to select reputable brands with good manufacturing practices using high quality ingredients when purchasing CBD blue gummies for ED. Ensure that you choose items whose potency and purity levels have been tested by third party laboratories so as to obtain safe and effective products. Besides, you should consider the purity levels of cannabinoids including CBD contained in each dose because higher doses may be necessary for severe erectile dysfunction cases.

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In brief, CBD Blue Gummies are a natural and effective way for men to address their sexual health and performance issues. These gummies combine ingredients such as CBD, L-arginine, and horny goat weed to boost blood flow, reduce inflammation, and improve sex drive. They are simple to use, private items that have limited side effects compared to regular medicines for ED.

If one is having erectile dysfunction difficulties or simply wants an improved sexual experience they might want to think about using CBD Blue Gummies as an alternative choice which is safe and natural at the same time. Talk to your doctor about finding the best product as well as dosage based upon what you require so that you may enjoy better sexual health combined with greater satisfaction. It is through taking these tablets called CBD Blue Gummies that one would be in charge of his/her sexual wellness leading them into rediscovering their intimacy with renewed pleasure henceforth.

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