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Quelle est la différence entre le CBD et le THC ? 🤔 Pourtant il s’agit de 2 cannabinoides de la même plante… Le Chanvre. Alors pourquoi l’un est légal et pas l’autre ?? 🧐 Le nom latin de Chanvre est : CANNABIS ! Tout est dit… Ces deux plantes ne sont qu’une seule 🌱 L’homme dans son besoin de contrôle à voulu séparer ce qui n’est qu’UN. Apres la 1er guerre mondiale différents lobbies ont créé le Chanvre industriel (sans THC mais avec le CBD) et le Cannabis récréatif (avec THC et CBD) Originellement cette plante a dans ses feuilles et ses fleurs des principes actif que sont : Les Cannabinoides, les terpènes, les flavonoïdes. Le CBD et le THC sont les principaux Cannabinoides de cette plante, mais il y en à une centaine. Seul le THC est psychoactif, c’est lui qui crée « l’ivresse » ou le « hight » quand on consomme du Cannabis. Le CBD n’à aucun effet psychoactif il est relaxant. Vous pouvez consommer du chanvre sous toutes ses formes sans aucun risque de « hight ». Seulement voilà… Si cela parait simple, aujourd’hui des études scientifiques démontrent que le THC a aussi des effets thérapeutiques très intéressants… L’association de tous les cannabinoides aurait un spectre thérapeutique beaucoup plus large.. Curieux d’avoir votre avis sur le sujet 👇
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This is one of the KEY messages when educating physicians and other healthcare practitioners. Medical cannabis is the umbrella term for any kind of cannabinoid used therapeutically, however, not all cannabinoids are created equally and it is very important to know the differences between THC, CBD, and other cannabinoids. It is also crucial to know when to use ingested or inhaled cannabinoids, topicals, patches, sublingual strips, suppositories, etc. and what the different ratios and concentrations are. Even within the literature, you'll see medical cannabis broadly mentioned without any specific cannabinoid or milligram dosage discussed, it’s laughable when someone will cite the so-called harms of cannabis and reference studies or news articles that don’t even drill down to whether it was CBD or THC or even how much THC was being used. This is one of the major factors limiting the widespread adoption of medical cannabis amongst practitioners—along with decades of research exclusively investigating the harms rather than the benefits. #medicalcannabis #endocannabinoidsystem #cannabinoids
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www.youshockedtv.blogspot.com Cnn Medical marijuana and the entourage effect In the early 1960s, a young postdoctoral student stumbled onto something that puzzled him. After reading the literature on cannabis, he was surprised to see that while the active compound in morphine had been isolated from opium poppies 100 years before and cocaine isolated from coca leaves around the same time, the active component of marijuana was still unknown. This simple observation launched his life's work. That young Israeli researcher, Raphael Mechoulam, is now a heavily decorated scientist, recently nominated for the prestigious Rothschild Prize. More than 50 years ago, however, he had trouble starting his scientific journey. By 1963, he determined the structure of cannabidiol (CBD), an important component of marijuana. A year later, he became the first person to isolate delta-9 tetrahydrocannabinol (THC), the psychoactive ingredient in marijuana. Over the ensuing decades, Mechoulam and his team continued to isolate numerous compounds from the cannabis plant. Their work also went a long way toward illuminating how the drug works in the brain. When Mechoulam's team identified the first known endogenous cannabinoid, a chemical actually made by the brain itself, he named it "anandamide." In the Sanskrit language, ananda means "supreme bliss," which gives us some insight into what Mechoulam thinks of cannabinoids overall. It was halfway through our long afternoon discussion that Mechoulam, now 83, pulled out a paper he had written in 1999, describing something known as "the entourage effect." Think of it like this: There are more than 480 natural components found within the cannabis plant, of which 66 have been classified as "cannabinoids." Those are chemicals unique to the plant, including delta-9-tetrahydrocannabinol and cannabidiols. There are, however, many more, including: -- Cannabigerols (CBG); -- Cannabichromenes (CBC); -- other Cannabidiols (CBD); -- other Tetrahydrocannabinols (THC); -- Cannabinol (CBN) and cannabinodiol (CBDL); -- other cannabinoids (such as cannabicyclol (CBL), cannabielsoin (CBE), cannabitriol (CBT) and other miscellaneous types). Other constituents of the cannabis plant are: nitrogenous compounds (27 known), amino acids (18), proteins (3), glycoproteins (6), enzymes (2), sugars and related compounds (34), hydrocarbons (50), simple alcohols (7), aldehydes (13), ketones (13), simple acids (21), fatty acids (22), simple esters (12), lactones (1), steroids (11), terpenes (120), non-cannabinoid phenols (25), flavonoids (21), vitamins (1), pigments (2), and other elements (9). Minister's daughter: Cannabis "a gift from God" Here is the important point. Mechoulam, along with many others, said he believes all these components of the cannabis plant likely exert some therapeutic effect, more than any single compound alone. While science has not yet shown the exact role or mechanism for all these various compounds, evidence is mounting that these compounds work better together than in isolation: That is the "entourage effect." Take the case of Marinol, which is pure, synthetic THC. When the drug became available in the mid-1980s, scientists thought it would have the same effect as the whole cannabis plant. But it soon became clear that most patients preferred smoking marijuana to taking Marinol. Researchers began to realize that other components, such as CBD, might have a larger role than previously realized. To better understand the concept of the entourage effect, I traveled to the secret labs of GW Pharmaceuticals, outside London. In developing Sativex, a cannabis-based drug to treat multiple sclerosis, the company's chairman, Dr. Geoffrey Guy, told me the company ran into some of the same obstacles that Marinol faced. More than a decade of experiments revealed that a whole plant extract, bred to contain roughly the same amounts of THC and CBD in addition to the other components in the plant, was more effective in reducing the pain and spasms of MS than a medication made of a single compound. It could be that multiple individual compounds play a role, or it could be due to their interaction in the body; it could also be combination of both, Guy said. Now, maybe this all sounds obvious. After all, eating real fruits, vegetables and other plants provides better nutrition than just taking vitamin pills with one nutrient or mineral in each. Science is showing us that we can likely say the same about cannabis. As we move forward with creating medicines, like Charlotte's Web, for the patients who can benefit from cannabis -- this is an important point to keep in mind.
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