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Welcome to The Chemist Couple podcast! With GLP-1 medications like Mounjaro becoming more popular, are we overlooking the risks? From potential nutrient deficiencies to serious health concerns like pancreatitis and diabetic retinopathy, we break it all down. Don't let the hype overshadow the science! ⚠️
⏱️ Timestamps:
* 00:00 - The Rise of GLP-1s: Why Are They So Popular?
* 01:56 - Eating Less = Harm? The Hidden Risks
* 03:43 - Losing Lean Mass: What You Need to Know
* 04:55 - The Risk of Vitamin Deficiencies
* 05:58 - Can You Keep the Weight Off? Leptin Explained
* 07:51 - Lifestyle Changes: Key to Long-Term Success
* 10:18 - The ‘Golden Dose’: A Dangerous Shortcut?
* 11:57 - ‘Microdosing’ GLP-1s: Risky & Unlicensed!
* 14:31 - Surgery & Aspiration: A New GLP-1 Warning
* 18:36 - Just How Powerful Are GLP-1s?
* 19:32 - Diabetic Retinopathy: An Overlooked Side Effect
* 22:05 - Pancreatitis: A Rare but Serious Risk
* 23:55 - Fertility, Pregnancy & Breastfeeding: What’s Safe?
* 29:20 - Planning a Pregnancy? Here’s What to Consider
* 30:21 - Final Thoughts: Are GLP-1s Worth the Risk?
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📚 Studies Referenced in This Episode:
* Guyton & Hall Medical Physiology (14th Edition) – General physiology overview
* Rang & Dale’s Pharmacology (10th Edition) – General pharmacological overview
* Electronic Medicines Compendium (EMC): Mounjaro (tirzepatide) Summary of Product Characteristics – Read Here
* Diabetes & Primary Care, Vol 23 No 4 (2021): GLP-1 receptor agonists and diabetic retinopathy – Read Here
⚠️ Disclaimer: This podcast is for informational purposes only and should not replace advice from a healthcare professional. If you have any questions, reach out to us. Thanks for watching!
When it comes to weight loss medications, people are always on the lookout for new options that can help them shed those extra pounds without having to resort to extreme measures. One such medication that has been generating buzz in the weight loss community is semaglutide. Originally approved for the treatment of type 2 diabetes, this drug has been gaining attention for its potential off-label use as a weight loss aid. But is semaglutide officially approved for weight loss? In this article, we will explore the current status of semaglutide as a weight loss medication.
What is Semaglutide?
Semaglutide is a medication that belongs to a class of drugs known as glucagon-like peptide-1 (GLP-1) receptor agonists. It works by mimicking the effects of a hormone called glucagon-like peptide-1, which helps regulate blood sugar levels by stimulating insulin secretion and reducing glucose production in the liver. In addition to its benefits for controlling blood sugar levels in people with diabetes, semaglutide has also been shown to have a significant impact on weight loss.
Studies have found that semaglutide can help individuals lose a substantial amount of weight when used in combination with diet and exercise. In fact, some clinical trials have shown that people who take semaglutide can lose up to 15% of their body weight over the course of a year. This makes semaglutide a promising option for people who have struggled to lose weight through other means.
Despite its potential for weight loss, semaglutide has not yet been officially approved by the U.S. Food and Drug Administration (FDA) for this indication. As of now, the FDA has only approved semaglutide for the treatment of type 2 diabetes. However, that has not stopped some doctors from prescribing semaglutide off-label for weight loss purposes. This practice is legal and common in the medical field, but patients should be aware that using medications off-label may not be covered by insurance or come with the same level of oversight as FDA-approved treatments.
Current Research on Semaglutide for Weight Loss
Research on semaglutide for weight loss is ongoing, with several clinical trials currently underway to further investigate its efficacy and safety in promoting weight loss. One of the largest trials to date is the STEP program, which includes several studies that evaluate the effects of semaglutide on weight loss in different populations, including people with obesity, prediabetes, and type 2 diabetes.
Preliminary results from these studies have shown that semaglutide can lead to significant weight loss in a broad range of individuals, regardless of their starting weight or metabolic health. In addition to its effects on weight, semaglutide has also been shown to have other beneficial effects on cardiovascular health, such as reducing the risk of heart attacks and strokes.
Despite these promising results, more research is needed to fully understand the long-term effects of semaglutide on weight loss and overall health. In the meantime, some experts caution that more data is needed before semaglutide can be widely recommended as a weight loss medication. Patients who are considering using semaglutide for weight loss should consult with their healthcare provider to discuss the potential risks and benefits of this treatment option.
Potential Side Effects of Semaglutide
Like all medications, semaglutide can cause side effects in some people. The most common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation. These side effects are usually mild and tend to improve over time as the body adjusts to the medication. However, some people may experience more serious side effects, such as pancreatitis or gallbladder problems. It is important to talk to your doctor if you experience any severe or persistent side effects while taking semaglutide.
In rare cases, semaglutide has been associated with a type of thyroid cancer called medullary thyroid carcinoma (MTC). While the risk of developing MTC from taking semaglutide is low, it is still important to be aware of this potential side effect and talk to your doctor if you have any concerns. It is also recommended that people with a personal or family history of MTC avoid taking semaglutide.
Before starting treatment with semaglutide, it is important to discuss your medical history and any pre-existing conditions with your healthcare provider. Semaglutide may not be suitable for everyone, especially those with a history of pancreatitis, thyroid problems, or certain types of cancer. Your doctor can help determine if semaglutide is the right choice for you based on your individual health needs and goals.
Conclusion
While semaglutide shows promise as a weight loss medication, it has not yet received official approval for this indication. Research on semaglutide for weight loss is ongoing, and more data is needed to fully understand its potential benefits and risks. In the meantime, some doctors may prescribe semaglutide off-label for weight loss, but patients should be aware of the limitations and uncertainties associated with this practice. If you are considering using semaglutide for weight loss, be sure to consult with your healthcare provider to discuss the best treatment options for your individual needs.
FAQ
Is semaglutide approved for weight loss?
No, semaglutide is not currently approved by the FDA for weight loss. It is only approved for the treatment of type 2 diabetes at this time.
Can I take semaglutide for weight loss off-label?
Yes, some doctors may prescribe semaglutide off-label for weight loss. However, patients should be aware of the potential risks and limitations associated with using medications off-label.
What are the side effects of semaglutide?
Common side effects of semaglutide include nausea, vomiting, diarrhea, and constipation. More serious side effects, such as pancreatitis and thyroid cancer, are rare but possible.
Is semaglutide safe for everyone?
Semaglutide may not be suitable for everyone, especially those with a history of pancreatitis, thyroid problems, or certain types of cancer. It is important to discuss your medical history with your healthcare provider before starting treatment with semaglutide.
What should I do if I experience side effects while taking semaglutide?
If you experience severe or persistent side effects while taking semaglutide, it is important to contact your doctor right away. They can provide guidance on how to manage side effects or adjust your treatment plan as needed.
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this is a video to document Jimin's weight loss journey through the years. I hope he realizes that he is enough & I know we all do. Love yourself park chim chim ❤️
Watch in HD! Only responsible for the edits :)
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* I'm not a nutritionist nor am I a doctor all information given has been gathered by personal experience and information that I researched and compiled over the years. Always consult a physician before starting a new diet, eating regiment, or workout plan.
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