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This episode explores the evolving role of GLP-1 agonists in rheumatology, highlighting their potential to influence weight, inflammation, and overall disease activity. Our guest expert unpacks how adipose tissue contributes to systemic inflammation and why managing body weight is crucial in the treatment of rheumatic diseases. We delve into the underlying science, real-world clinical applications, and the exciting future of incorporating GLP-1 therapies into comprehensive rheumatologic care—offering fresh insight into a therapeutic class with game-changing potential.
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James Newburrie's Weight Loss Journey and Insights on GLP-1 Medications In this episode of The Downsized Dish, host Laraine Durham sits down with James Newburrie for his third interview to discuss his ongoing weight loss journey using GLP-1 medications like Mounjaro. James shares his experiences, challenges, and achievements over the past six months, including a substantial weight loss of 93 pounds. Despite facing financial and emotional hurdles, James remains optimistic and determined. The conversation covers the impact of these medications on his lifestyle, mental health, and the societal stigma surrounding weight loss. Additionally, they discuss the importance of self-acceptance, creating a supportive community, and plans for the future. Tune in to hear inspiring stories and get valuable insights on living healthier with GLP-1 medications. DOWNSIZED GLP-1 COMPANION PRODUCT STORE: https://thedownsized.org/downsized-store Join CLUB DOWNSIZED: https://www.youtube.com/@thedownsized/join DOWNSIZED WEBSITE: https://thedownsized.org/ FOR SPONSORSHIPS, BRAND DEALS & COLLABS: https://thedownsized.org/contact/ 00:00 Introduction to the Downsized Dish 00:52 Meet James Newburrie: A Weight Loss Journey 01:32 James' Weight Loss Progress and Medication 05:11 Challenges and Costs of Medication in Australia 07:52 Reflecting on Past Interviews and Public Perception 11:45 The Psychological Impact of Weight Loss 17:19 Changes in Eating Habits and Lifestyle 21:30 Navigating Stress and Maintaining Progress 31:26 Reflecting on the Journey and Future Goals 34:08 Embracing a New Relationship with Food 35:48 Unexpected Benefits of Exercise 37:24 Unlearning Diet Culture 39:13 The Emotional Journey of Weight Loss 41:20 The Role of Medication in Weight Loss 45:47 Navigating Social and Personal Changes 51:52 Setting New Fitness Goals 56:42 The Importance of Self-Acceptance 01:02:41 Concluding Thoughts and Future Plans
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Here is why I quit the carnivore diet… Avoid fast food garbage and eat real foods. This is why I created Lineage Provisions. Giving you real foods in the most convenient way. Check us out: http://lineageprovisions.com/psmdyt The carnivore diet is a very powerful short-term intervention that helped me reverse all my gut and skin conditions and has helped thousands of people improve their overall health… If you are thriving, keep doing what you are doing… But if you are not, there are a few things to reconsider when structuring your diet… Healthy carbohydrates from fruit and honey are key to optimal hormonal health… There is no scientific evidence to suggest that carbohydrates from fruit and honey are harmful for humans… In this video, I am going to review many research studies on the benefits of carbohydrates for humans… It's always meat / organs / fruit / honey / raw dairy… This is an ANIMAL-BASED diet, and I believe this is the most optimal diet for humans on the planet... Check out my ANIMAL-BASED CALCULATOR here: https://www.paulsaladinomd.co/ab-guide#calculator 00:00 Intro 01:53 My story 04:42 The role of insulin 07:45 The pitfalls of keto diets 12:26 The importance of carbohydrates 16:43 Fruit and honey 22:35 What's the takeaway? STUDIES 👇 Insulin's impact on renal sodium transport and blood pressure in health, obesity, and diabetes - https://pubmed.ncbi.nlm.nih.gov/17686957/ Fructose in healthy adults - https://pubmed.ncbi.nlm.nih.gov/3781328/ Fructose in mice - https://pubmed.ncbi.nlm.nih.gov/19637282/ A Short-Term Ketogenic Diet Impairs Markers of Bone Health in Response to Exercise - https://pubmed.ncbi.nlm.nih.gov/32038477/ Changes of thyroid hormonal status in patients receiving ketogenic diet - https://pubmed.ncbi.nlm.nih.gov/28076316/ Dietary macronutrient content alters cortisol metabolism independently of body weight changes in obese men - https://pubmed.ncbi.nlm.nih.gov/17785367/ Isocaloric carbohydrate deprivation induces protein catabolism despite a low T3-syndrome in healthy men - https://pubmed.ncbi.nlm.nih.gov/11167929/ Modification of immune responses to exercise by carbohydrate, glutamine and anti-oxidant supplements - https://pubmed.ncbi.nlm.nih.gov/11050539/ Ketosis leads to increased methylglyoxal production on the Atkins diet - https://pubmed.ncbi.nlm.nih.gov/16037240/ Supplemental Watermelon Juice Attenuates Acute Hyperglycemia-Induced Macro-and Microvascular Dysfunction in Healthy Adults: https://pubmed.ncbi.nlm.nih.gov/34510203/ The Effect of Watermelon Juice Supplementation on Heart Rate Variability and Metabolic Response during an Oral Glucose Challenge - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967111/ Drinking orange juice increases total antioxidant status and decreases lipid peroxidation in adults -https://pubmed.ncbi.nlm.nih.gov/24476220/ Purple grape juice improves endothelial function and reduces the susceptibility of LDL cholesterol to oxidation - https://pubmed.ncbi.nlm.nih.gov/10477529/ Effects of Tart Cherry Juice on Biomarkers of Inflammation and Oxidative Stress in Older Adults - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413159/ A Review on the Protective Effects of Honey against Metabolic Syndrome - https://www.mdpi.com/2072-6643/10/8/1009 Effects of natural honey consumption in diabetic patients: an 8-week randomized clinical trial - https://pubmed.ncbi.nlm.nih.gov/19817641/ Follow me on social media: Instagram: https://www.instagram.com/paulsaladinomd Tik Tok: https://www.tiktok.com/paulsaladinomd2 Twitter: https://twitter.com/paulsaladinomd Send a message to the team: [email protected] Disclaimer: Dr. Paul Saladino received his medical degree from the University of Arizona Medical School. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Saladino is a licensed physician in California, but he no longer practices in any state and does not see patients so he can focus on educating people as a full time activity. This video is for general informational purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, and prescription or recommendation. It does not create a doctor-patient relationship between Dr. Saladino and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. #carnivore #animalbaseddiet #dayofeating #carnivorediet #animalbased #fitness #health #seedoils
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