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In this episode, Dr. Michele Matarazzo interviews Prof. Tom Foltynie about the recently published phase 3 clinical trial of exenatide as a disease-modifying therapy for Parkinson’s disease in The Lancet. While the findings were disappointing, ongoing post-hoc analyses aim to understand the discrepancy with previous phase 2 results and explore how they might shape the future of exenatide and other GLP-1 agonists in neurodegenerative disorders.
Read the article. (https://pubmed.ncbi.nlm.nih.gov/39919773/)
How Protein Is Good For Weight Loss High Protein Foods For Fat Loss Shivangi Desai
GLP-1 계열의 비만·당뇨 치료제가 올해 가장 주목받는 신약이 될 것이라는 전망이 나왔습니다.
한국바이오협회 바이오경제연구센터가 분석한 글로벌 금융데이터 서비스 기업 피치북의 보고서에 따르면 올해 바이오 벤처캐피털(VC) 투자는 GLP-1 계열의 치료제와 AI 신약 개발사에 집중적으로 이뤄질 것이라고 예상했습니다.
GLP-1 계열의 비만·당뇨 신약이 글로벌 트렌드로 부상하고 있는 상황에서 국내 개발사와 임상 진행 상황에 대한 관심도 높아지고 있습니다.
개발 속도는 주사제형이 가장 빠릅니다. HK이노엔은 지난해 5월 중국 사이윈드 바이오사이언스로부터 도입한 GLP-1 계열의 신약 후보 물질에 대한 임상3상 시험계획 승인신청(IND)을 식품의약품안전처에 제출했다고 공시했습니다.
한미약품은 내년 하반기 출시를 목표로 임상 3상이 진행 중인 에페글레나타이드를 핵심 신약 파이프라인으로 밀고 있습니다.
한미약품은 에페글레나타이드가 위고비 수준의 체중감량 효과뿐만 아니라, GLP-1 계열 치료제의 고질적인 문제점인 복통과 구토 등 위장관 장애 부작용을 크게 개선하는데 주력하고 있습니다.
이밖에 일동제약의 자회사 유노비아는 경구제형으로 대원제약은 마이크로니들 개발 전문기업 라파스와 손잡고 패치형 비만치료제로 임상 1상을 진행하고 있습니다.
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감사합니다.
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Are you over eating???
Incan guarantee most people are over eating when it comes to losing weight!
Concentrate on portion control, the size of your portions could probably be cut in half tbh.
If your trying to lose weight then think about tracking your calories for a few weeks so you can educate yourself on the amount of calories and macros are in your meals.
Then you can make an educated decision on what to put on your plate and actually make progress towards your goals.
Embrace the hunger at times, your gonna feel hungry when your in a calorie deficit! Its meant to feel that way!
Stay in that deficit as long as you can, increase food only when you need to, not when you feel like it.
If your not sure, get a coach to help you!
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27 Bmi Required Link To Telehealth In Bio Glp1 Semaglutide Weightloss
30-Min Simple STANDING Workout Challenge To Lose Belly Fat in 10 Day (Get A Flat Belly Fast )
✅ Recommended Workout Routine (SAVE VIDEO FOR FUTURE)
Week 1 👉🏼 Do It 3 Days a Week
Week 2 👉🏼 Do It 4 Days a Week
Week 3 👉🏼 Do It 5 Days a Week
Week 4 and beyond 👉🏼 Do It 6 Days a Week
Timestamps
00:00 - Intro
00:05 - Start Of Workout
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Ozempic Uncovered Exploring Weight Loss Benefits And Potential Risks
Obesity is a significant public health concern worldwide, with more than one-third of adults in the United States considered to be overweight or obese. In recent years, there has been a growing interest in the use of semaglutide, a medication originally developed to treat type 2 diabetes, for weight loss. Semaglutide works by mimicking the effects of a hormone called glucagon-like peptide-1 (GLP-1), which helps regulate blood sugar levels and food intake.
Semaglutide Doses for Weight Loss: Guidelines and Recommendations
Studies have shown that semaglutide can lead to significant weight loss in individuals with obesity or overweight when combined with diet and exercise. However, determining the right dose of semaglutide can be challenging, as it varies depending on individual factors such as age, weight, and medical history. In this article, we will discuss the guidelines and recommendations for semaglutide doses for weight loss.
Starting Dose
The starting dose of semaglutide for weight loss is typically 0.25 mg once a week, which is lower than the dose used for treating diabetes. This lower dose helps minimize side effects such as nausea and vomiting, which are common when starting on semaglutide. The dose can be gradually increased over time based on individual response and tolerance.
Titration
Titration is the process of adjusting the dose of semaglutide to achieve the desired weight loss goals. Most individuals will eventually reach a maintenance dose of 2.4 mg once a week, which has been shown to be effective in promoting weight loss. It is essential to work closely with a healthcare provider to monitor progress and make any necessary adjustments to the dose.
Monitoring and Side Effects
It is crucial to monitor for side effects while taking semaglutide for weight loss. Common side effects include nausea, vomiting, diarrhea, and constipation, which may improve over time. More severe side effects such as pancreatitis and gallbladder disease are rare but require immediate medical attention. Regular check-ups with a healthcare provider are essential to ensure the safe and effective use of semaglutide.
Combination Therapy
Semaglutide can be used alone or in combination with other weight loss medications to enhance its effectiveness. Combining semaglutide with medications such as phentermine or orlistat may lead to additional weight loss benefits. However, it is essential to consult with a healthcare provider before combining medications to avoid potential drug interactions or adverse effects.
Long-Term Use
Long-term use of semaglutide for weight loss may be necessary to maintain the achieved weight loss. It is essential to follow a healthy diet and exercise regimen while taking semaglutide to maximize its benefits. Regular monitoring and follow-up with a healthcare provider are essential to ensure long-term success and address any potential concerns.
As with any medication, it is essential to consult with a healthcare provider before starting semaglutide for weight loss to determine the right dose and ensure safe and effective use. By following the guidelines and recommendations outlined in this article, individuals can achieve significant weight loss with semaglutide while minimizing side effects and maximizing benefits.
My Routine For Weight Loss From 60kgs To 50kgs Basic Tips
Hey guys! So today was the last day of my first week on the diet and I'm down 5.1 lbs and 1"! The diet has been relatively easy and encourages healthy eating and getting creative with veggie recipes.
Excuse how I look in this video. I was really tired today after my workout :)
Asmr Dr Dmitri Weight Loss Hypnosis Session Also For Relaxation And Happiness
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5 Simple Yoga Exercises To Lose Belly Fat At Home In 1 Week | Best Yoga Asanas for Losing Weight Loss Quickly & Easily
Yoga is a group of physical, mental, and spiritual practices or disciplines which originated in ancient India. Yoga means union of the individual consciousness or soul with the Universal Consciousness or Spirit.
The science of Yoga imbibe itself the complete essence of the Way of Life, including - Gyan Yoga or philosophy, Bhakti Yoga or path of devotional bliss, Karma Yoga or path of blissful action, and Raja Yoga or path of mind control. Raja Yoga is further divided into eight parts. At the heart of the Raja Yoga system, balancing and unifying these various approaches, is the practice of Yoga Asana.
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