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This is a brief video on pharmacologic agents that help reduce weight or control weight. I created this presentation with Google Slides. Image were created or taken from Wikimedia Commons I created this video with the YouTube Video Editor. ADDITIONAL TAGS: Anti-obesity medication Pharmacological agents that reduce weight or help control weight Phentermine Orlistat Phentermine/ topiramate Lorcaserin Bupropion/ naltrexone Liraglutide By James Heilman, MD - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=4854133 Phentermine Approved by FDA in 1959 Mechanism: releases norepinephrine Short term use (3 to 6 months) Not approved for long term use Cheap Phentermine Orlistat Phentermine/ topiramate Lorcaserin Bupropion/ naltrexone Liraglutide Orlistat Approved by FDA in 1999 Mechanism: inhibits lipase (gastric and pancreatic) Therefore, decrease in fat breakdown and absorption Side effects: GI disturbance (cramps, fecal incontinence, diarrhea (specifically steatorrhea)), fat soluble vitamin deficiency (vitamins DEAK) → give multivitamins Good for CAD patients or those at risk for CVD Available over-the-counter Phentermine Orlistat Phentermine/ topiramate Lorcaserin Bupropion/ naltrexone Liraglutide Phentermine/topiramate Approved by FDA in 2010 Phentermine mechanism: releases norepinephrine Topiramate mechanism: blocks Na channels, modulates GABA receptor to increase action Used for migraine prophylaxis and seizures (simple, complex, tonic-clonic) Side effects: mental sedation, kidney stones Phentermine Orlistat Phentermine/ topiramate Lorcaserin Bupropion/ naltrexone Liraglutide Lorcaserin Approved by FDA in 2012 Mechanism: agonists serotonin (5-HT2C) receptor Side effects: dizziness, dry mouth, GI disturbance (nausea, vomiting, diarrhea), fatigue, headaches Phentermine Orlistat Phentermine/ topiramate Lorcaserin Bupropion/ naltrexone Liraglutide Bupropion/naltrexone Approved by FDA in 2014 Bupropion mechanism: increase norepinephrine and dopamine levels Naltrexone mechanism: opioid antagonist Side effects: anxiety, headaches Good for patients also struggling with smoking cessation (bupropion approved for smoking cessation) Phentermine Orlistat Phentermine/ topiramate Lorcaserin Bupropion/ naltrexone Liraglutide Liraglutide Approved by FDA in 2015 Mechanism: agonizes the GLP-1 receptor (GLP-1 analog) Subcutaneous injection Side effects: pancreatitis, nausea, vomiting Phentermine Orlistat Phentermine/ topiramate Lorcaserin Bupropion/ naltrexone Liraglutide
Semaglutide Has Shown Efficacy Resulting In Weight Loss Ranging From 15 To 20 Weightloss
In this video, we're taking a closer look at two popular options for weight management: berberine and semaglutide. We're not just skimming the surface here – we're delving deep into the research to bring you all the insights you need. You'll discover what a 2020 meta-analysis of randomized controlled trials revealed about berberine's impact on body weight, BMI, waist circumference, and inflammation levels. Spoiler alert: while berberine does show some promise in helping shed a few pounds, we're comparing its effects to the impressive 10-20% weight loss seen with semaglutide. But don't worry, we're not here to dismiss berberine entirely. We'll explore its natural GLP-1 increasing effects and anti-diabetic properties, while also acknowledging the powerful punch packed by pharmaceutical options like semaglutide and metformin, especially for those dealing with medical conditions. Our goal? To give you the lowdown on both options, empowering you to make informed decisions about your health journey. So, grab a snack, get comfy, and join us as we navigate the world of weight management together. #semaglutide #ozempicweightloss #ozempic #semaglutideweightloss #wegovy #wegovyweightloss #berberine
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