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In this episode of the Pharm So Hard Podcast, the hosts discuss GLP-1 receptor agonists, a class of medications used to manage blood sugar levels in patients with type 2 diabetes and to treat obesity. They provide an overview of the history and development of GLP-1 receptor agonists, highlighting their clinical superiority and various benefits. The hosts also explain the role of GLP-1s in the body, including their glucose-dependent insulin secretion and effects on gastric emptying. They discuss the impact of GLP-1s on hunger and mental health, emphasizing the reduction of food noise and improvement in satiety levels. Additionally, they differentiate GLP-1 receptor agonists for diabetes and weight loss and explore their indications and guideline positioning.
Takeaways
• GLP-1 receptor agonists are a class of medications used to manage blood sugar levels in patients with type 2 diabetes and to treat obesity.
• GLP-1 receptor agonists have shown clinical superiority to other anti-hyperglycemic drugs, improving glycemic control, reducing weight loss and blood pressure, and providing cardio-protective benefits.
• GLP-1s increase glucose-dependent insulin secretion, block glucagon secretion, and slow gastric emptying, leading to improved blood sugar control and increased satiety.
• GLP-1 receptor agonists have a positive impact on mental health, reducing food noise and helping individuals make healthier food choices.
• Different GLP-1 receptor agonists have specific indications for diabetes and weight loss, and their use is guided by clinical guidelines.
• GLP-1 receptor agonists are FDA-approved for improving glycemic control in patients with type 2 diabetes and for the treatment of obesity.
• The choice of GLP-1 receptor agonist depends on factors such as comorbidities, weight loss goals, and patient preferences.
• GLP-1 receptor agonists have different dosing regimens, and the specific dose may vary based on the indication and the product.
• Common side effects of GLP-1 receptor agonists include nausea, vomiting, and diarrhea, but these side effects often improve with continued use and proper management. GLP-1 agonists can cause loss of appetite as a side effect.
• GLP-1s are being used off-label for conditions such as NAFLD and depression.
• GLP-1s may have positive effects on bone health and blood pressure.
• The high cost of GLP-1s poses challenges for patient access.
Chapters
00:00 Introduction to GLP-1 Receptor Agonists
01:12 History and Development of GLP-1 Receptor Agonists
06:14 The Role of GLP-1s in the Body
09:38 Effects of GLP-1s on Hunger and Mental Health
11:17 Differentiation of GLP-1 Receptor Agonists for Diabetes and Weight Loss
11:44 Indications and Guideline Positioning of GLP-1 Receptor Agonists
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🔥 Zone 2 cardio is low-to-moderate intensity exercise where you can still talk comfortably, and your body mostly burns fat for fuel.
It’s called Zone 2 because it falls between 60–70% of your maximum heart rate, right after the lightest activity (Zone 1) and before things get more intense (Zones 3–5).
Think of it as the “fat-burning zone” that builds endurance without wearing you out..
💡 Focus: Staying aerobic, maximizing fat use, and building cardio without burnout.
🧠 Smart is better than brutal. Train with intention.
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क्या वजन कम करने के लिए आपको अपनी पसंदीदा चीज़ें छोड़नी पड़ेंगी? क्या हेल्दी रहने का मतलब सिर्फ सख्त डाइटिंग और घंटों की एक्सरसाइज़ है? Qualified Dietitian Saloni, जिन्होंने खुद 55 किलो वजन कम किया, इस वीडियो में इन सभी मिथकों को तोड़ेंगी!
Saloni, जो @myfemilywellness की फाउंडर हैं, 8+ सालों से Nutrition Science में काम कर रही हैं और 15,000+ लोगों की लाइफ ट्रांसफॉर्म कर चुकी हैं। उनकी टीम 100+ Qualified Dietitians के साथ मिलकर PCOD, डायबिटीज, थायरॉयड, एंडोमेट्रियोसिस जैसी मेडिकल कंडीशन्स को मैनेज करने में मदद करती है।
इस वीडियो में Saloni अपनी 85 किलो से फिटनेस जर्नी के बारे में बता रही हैं। उन्होंने खुद भी वजन घटाने के लिए कई गलतियां कीं, लेकिन Nutrition Science की पढ़ाई के बाद बिना किसी एक्सट्रीम डाइट के 35 किलो वजन कम किया। वे बताती हैं कि हेल्दी डाइटिंग का मतलब खाना छोड़ना नहीं, बल्कि सही तरीके से संतुलित खाना है।
Saloni मानसिक स्वास्थ्य को भी उतना ही ज़रूरी मानती हैं जितना कि शारीरिक स्वास्थ्य। वे बताती हैं कि क्रैश डाइटिंग के बजाय, हमें खाना एंजॉय करते हुए हेल्दी रहने की कोशिश करनी चाहिए। Junk food भी सही मात्रा में खाया जा सकता है, अगर हम सही बैलेंस बनाए रखें।
तो अगर आप भी फिट रहना चाहते हैं बिना किसी सख्त डाइटिंग के, तो यह वीडियो ज़रूर देखें!
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Do you really need to give up your favorite foods to lose weight? Does staying healthy mean following strict diets and spending hours exercising? Qualified Dietitian Saloni, who has personally lost 55 kgs, breaks these myths in this video!
Saloni, the founder of @myfemilywellness, has been working in Nutrition Science for over 8 years and has transformed the lives of 15,000+ people. Her team of 100+ qualified dietitians helps women manage PCOD, diabetes, thyroid, endometriosis, and other medical conditions.
In this video, Saloni shares her fitness journey from 85 kgs to a healthy lifestyle. She made many mistakes while trying to lose weight, but after studying Nutrition Science, she successfully lost 35 kgs without extreme dieting. She emphasizes that healthy eating is not about cutting out food but about maintaining the right balance.
Saloni also highlights the importance of mental health along with physical health. She explains that instead of crash dieting, we should enjoy our meals while making healthy choices. Even junk food can be consumed in moderation if we maintain a proper balance.
So, if you want to stay fit without following extreme diets, make sure to watch this video only on Josh Talks Hindi!
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The views, information, opinions, and beliefs expressed in this video are personal to the speaker and are expressed in good faith. Josh Talks is not, in any manner, supporting or endorsing the views, information, opinions, and beliefs of the speaker. Josh Talks is merely, in good faith, providing a platform and a channel for a diverse group of speakers to share their knowledge and learnings for general educational purposes only. Josh Talks is not responsible, and does not guarantee the accuracy, validity, or completeness of the views, information, opinions, and beliefs expressed by the speaker. Nothing in this video constitutes advice of any kind or manner.
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This video is only made for educational purposes
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Vous voulez perdre du poids et maigrir pour retrouver une meilleure santé et bouger plus facilement... Mais le tout sans avoir faim bien-sûr ! Avec ces 5 aliments (à intégrer dans une alimentation variée et équilibrée) vous allez pouvoir réduire la densité énergétique de votre alimentation tout en vous assurant une bonne satiété et éviter les grignotages entre les repas. Perdre du poids sans avoir faim, c'est important pour garder la motivation tout au long du régime. Soupes, potages, viande de dinde, fromage blanc, oeufs... Ces aliments rassasiants vont vous aider à mincir naturellement... le dernier, c'est pour un petit plaisir gustatif pour ne pas laisser la monotonie du régime s'installer.
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These gummies are groundbreaking because they merge quantum science with the advantages of the ketogenic diet. Quantum Keto Gummies have been created to enhance weight loss by increasing the body’s ability to burn fat through its natural metabolic processes using quantum energy. This article aims at discussing their advantages, which are why they are increasingly being adopted as a means of losing weight and enhancing one’s health.
Working Principle of Quantum Keto Gummies
Quantum Keto Gummies work by employing a rare blend of ingredients that have been scientifically tested to support ketosis, a state in which your body burns fat for energy rather than carbohydrates. For instance, these gummies bear exogenous ketones that increase the levels of ketones in your blood making it easy for you to enter into and stay within ketosis. In addition, other elements such as quantum energy have also been included in these Quantum Keto Gummies that many believe helps amplify fats melting inside your system thereby raising up your energy levels.
Presence of exogenous ketones initiates ketoisis when taking Quantum Keto Gummies. These types of gummy bears make remaining in this condition has become easier since they mimic naturally produced ketones while following a keto-based diet; thus allowing energy boosting fats burning out instead. The process is also assisted by stimulated quantum energy which makes you lose weight more quickly.
Unlike other typical weight loss supplements, Quantum Keto Gummies do not try to tackle weigh loss head-on; instead, they combine conventional ketogenic diets with alternative approaches involving quantum power. Such strategies set them apart from many other users who only focus on curbing their appetite so as to lose or maintain healthy weights.
Benefits of Quantum Keto Gummies
Outstanding among these is how easily can one get into and keep off ketosis comparing to any other supplement on the market today. These gummy bears provide some external source Ketone bodies that puts your body into ketosis faster and keeps you there longer, all resulting in more fat burning and faster weight loss besides the higher energy levels needed to reach your goals of losing weight.
Besides helping you get into ketosis, Quantum Keto Gummies will also help you manage your hunger as well as minimize cravings. The ingredients found in these gummies are meant to control your appetite and reduce sugar and carbohydrate cravings that usually derail efforts to lose weight. If you want to experience tasty treats without any interruptions towards your aim of losing a few pounds, include Quantum Keto Gummies in your daily regimen.
Additionally, Quantum Keto Gummies provide all-day energy with no crashes. Ketosis implies that the body is constantly breaking down fats which result in more power as well as improved mental performance. With a steady fuel supply all day long by means of Quantum Keto Gummies supporting ketosis, one can be alert throughout every moment of the day thus staying productive.
Why Choose Quantum Keto Gummies
There are several reasons why Quantum Keto Gummies should be chosen as a weight loss supplement. Firstly, these gummies contain a unique mix of ingredients that have been scientifically proven to back up ketosis and increase fat burning in the body. Unlike others, quantum ketosis Gummies combine exogenous ketones with quantum energy for holistic weight reduction.
Also, it is easy and convenient to integrate Quantum Keto Gummies into your everyday life. Instead of taking pills like traditional weight loss formulas, one can simply take some of these sweet treats at any time during the day. Thus, Quantum Keto Gummies will be found as an easy pick by those individuals leading busy lives yet still want to stay true to their slimming goals.
In addition, science supports Quantum Keto Gummie because they have been tested for safety and effectiveness. These gummy bears contain all those elements which enable you get more out of this product without any harm that might result in adverse effects afterwards. You can trust in choosing Quantum Keto Gummie as it’s safe and efficient.
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All in all, the combination of quantum science with ketogenic diet is what makes Quantum Keto Gummies different from other products on the market used for weight reduction. These gummies help burn fats while keeping your body energized throughout the day; thus boosting your ability to achieve and maintain ketosis levels. Due to their ease-of-use and tasty flavors; therefore anyone who craves something sweet will naturally think about them when planning losing weight today!
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Best Yoga Poses For MIGRAINE HEADACHE PAIN RELIEF.
Yoga is not only a holistic approach to getting your body relieved from pains, but it also makes your body stronger to fight other illnesses as they make their ways close to you. Yoga is as much effective in combating #migraines as it is in fighting any other pain. Specific yoga poses can target tension and #stress, which may be contributing to your #headaches.
You can switch to yoga along with your regular medication for migraines. Yoga can provide more than just physical fitness. It assists your body and mind to relax and calm, also helps fight #anxiety and depression.
Yoga is an ancient practice, whose practitioners consider it to be more than just a form of exercise. It promotes a sense of holistic living through the combination of breathing techniques and asanas. It has no side effects. It helps battle ailments while correcting postures, energy flow, and overall health. All it takes is a few minutes of your time to practice yoga every day and keep problems like a migraine at bay.
Migraines are more intense than frequent headaches. They’re typically characterized by a throbbing pain on one side of the head. They’re often accompanied by nausea, dizziness, and sensitivity to light and sound. Migraines can last anywhere from a few hours to a few days.
# So here are a few poses to help you fight a migraine attack.
#PADMASANA (LOTUS POSE YOGA)
The Padmasana or the Lotus Pose is a meditative posture that relaxes the mind and clears out the head, thereby reducing the headaches. Don’t be deceived by how simple it looks, though. It can be quite a task to master this sitting pose.
To do this pose, sit on the floor with your legs stretched out. Now bend your right knee and place the foot on the left thigh. Now bend your left knee and place the foot on the right thigh. Make sure your heels point upward and are close to the abdomen. Hold for a few seconds.
#HASTAUTTANASANA YOGA (HAND RAISING POSE)
Hasta uttanasana or Hand raising pose helps you stretch your body and increases blood circulation. It enhances the amount of oxygen in the head and releases stress, thereby, reducing the pain.
Stand erect and raise both the hands above the head. Let there be shoulders length between the two arms. Bend the trunk and head backward to create a slight curve. Raising the arms and bending the trunk backward is done at the same time. Breathe in deeply while raising the arms.
#MARJARIASANA (YOGA CAT STRETCH POSE)
Marjariasana or The Cat Stretch is a great mind and muscle relaxant. It also improves your breathing and allows you to release stress. All of these factors help in getting rid of the pain and symptoms of a migraine.
Come down on your hands and knees. While inhaling, suppress your back and raise your head up. Hold for a few seconds and then exhale while arching your back and pulling in your belly. Repeat for ten times and then relax.
#PASCHIMOTTANASANA (SEATED FORWARD BEND POSE)
Paschimottanasana or Seated forward bend pumps a new lot of blood to your head. It ensures the absorption of more nutrients, and fresh oxygen in the head, which automatically reduces the pain. The asana also works on the digestive system. So if your headache is stomach related, you will find relief instantly.
Sit on the floor with your legs stretched out. Now slowly bend forward and try to press your big toes with your fingers. Hold for a few seconds and then relax.
#SHAVASANA (CORPSE POSE)
The Shavasana or the Corpse Pose is the ultimate climax to a great yoga session.
It brings about a deep state of rest in the body.
The body almost drifts into a meditative state and gets rejuvenated. This rejuvenation also helps in banishing migraines.
Lay on your back with your hands away from body and palms facing upward. Feet should be hip-width apart. Keep your neck and back straight and relax for a few seconds.
Practice these poses daily and see a remarkable relief in your suffering from a migraine.
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Study this GLP-1 Analogs mnemonic and other mnemonics with Pixorize.
GLP-1 Analogs are a class of drugs that include exenatide and liraglutide. These drugs are used to treat type 2 diabetes mellitus by lowering blood sugar levels. As their name suggests, these drugs work by imitating the actions of GLP1 in the body, which stimulates glucose-dependent insulin release and decreases glucagon release. These drugs also decrease gastric emptying and increase satiety. A common side effect of these drugs is nausea and vomiting, while a much rarer side effect is pancreatitis. The GLP1 analogs are also known to cause weight loss in patients. Finally, these drugs typically do not cause hypoglycemia in patients.
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0:00-0:16 Intro
0:17-2:43 Drug Names & Clinical Use
2:46-7:42 Mechanisms
7:43-11:07 Side Effects
11:08-12:10 Recap
The Science Behind Fasting And Its Benefits Indian Weight Loss Diet By Richa
📄 YouTube Video Description:
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Manufactured in an FDA-accredited facility with GMP certification, Puravive follows stringent safety protocols and quality controls. Packaged in easy-to-swallow capsules, each bottle contains 30 capsules of this non-GMO formula free from stimulants.
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00:35 - Puravive's Exotic Rice Method
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