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: Hello, healthcare heroes! The landscape of type 2 diabetes management has been significantly impacted by two powerful injectable medications as per Primary FDA Indication (: Ozempic from Novo Nordisk and Mounjaro from Eli Lilly.
Let's break down their differences and strengths.
Both Ozempic and Mounjaro are incretin mimetics, leveraging natural gut hormones.
• Ozempic® (Semaglutide) is a GLP-1 Receptor Agonist. It mimics Glucagon-Like Peptide-1, helping to lower blood sugar by stimulating insulin release when needed, slowing gastric emptying, and reducing glucagon secretion. Ozempic is available in pre-filled pens that deliver doses of 0.25 mg, 0.5 mg, 1 mg, and 2 mg per injection, with varying solution concentrations.
• Mounjaro® (Tirzepatide) takes a unique approach as a dual GLP-1 and GIP Receptor Agonist. By mimicking both GLP-1 and Glucose-Dependent Insulinotropic Polypeptide, it offers potentially more comprehensive effects on blood sugar control.
• Mounjaro is available as a subcutaneous injection in pre-filled single-dose pens with strengths of 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, or 15 mg per 0.5 mL.
So, how do they stack up in managing type 2 diabetes?
• Blood Glucose Control: Mounjaro has shown greater effectiveness at lowering A1C levels compared to Ozempic in clinical trials, attributed to its dual mechanism. For context, the A1C goal for most non-pregnant adults with diabetes is typically less than 7%, though this is always individualized based on patient factors like age, comorbidities, and risk of hypoglycemia.
• Weight Loss: While both can lead to weight loss, Mounjaro has demonstrated more significant weight loss in trials, even in type 2 diabetes patients, making it a compelling option for those with co-occurring obesity.
• Cardiovascular Protection: Ozempic has established proven cardiovascular benefits, reducing the risk of major adverse cardiovascular events in patients with type 2 diabetes and established cardiovascular disease. Mounjaro's cardiovascular outcomes are currently still being evaluated in dedicated trials
Common side effects for both are predominantly gastrointestinal: nausea, vomiting, diarrhea, and constipation. These often improve with time and careful dose titration.
Both carry a Boxed Warning regarding the risk of thyroid C-cell tumors, including medullary thyroid carcinoma, observed in rodent studies. They are contraindicated in patients with a personal or family history of MTC or MEN 2 syndrome (which Is a rare genetic polyglandular cancer syndrome. It is characterized by the 100% prevalence of medullary thyroid carcinoma (MTC)
Pancreatitis is another serious, rare side effect.
The choice between Ozempic and Mounjaro for type 2 diabetes management is highly individualized. It depends on factors like A1C goals which is a key indicator for blood glucose control in individuals with diabetes, weight management needs, cardiovascular risk, tolerability, and patient preferences. Always refer to the latest clinical guidelines and product prescribing information.
Sharpen your knowledge, and as we continue exploring modern therapeutics, let's turn our attention to the exciting advancements specifically in chronic weight management...
Celagen serves as a vital resource for physicians, nurses, pharmacists, and other allied health professionals seeking to deepen their understanding of advanced therapeutics. Specializing in rapidly evolving fields such as biologics and injectable medications for chronic diseases like obesity and type 2 diabetes, Celagen delivers expertly curated content designed for clarity and clinical relevance. We simplify complex scientific concepts, focusing on mechanisms of action, clinical indications, comparative effectiveness, safety profiles, and strategic considerations for patient management. Through engaging and accessible formats, Celagen aims to support HCPs in making informed decisions and optimizing patient care.
#Biologics #Healthcare #MedicalEducation #HCPs #Pharmacology #Immunology #Rheumatology #Oncology #Gastroenterology #Neurology #Dermatology #Biosimilars #Celagen #MedicineExplained
Shark Tank Keto Products A Comprehensive Overview
Hundreds of thousands of people around the world are now on weight loss drugs like Wegovy, known as GLP-1s. The food industry is taking notice too, with big companies leaning into more nutritional products to complement the effects of the drug. Deirdre Hipwell, who leads Bloomberg's team covering healthcare and consumer companies in Europe, joins Stephen Carroll to discuss.
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Understanding The Price Of Semaglutide Weight Loss Treatments
Happy New Yearto all my beautiful people 🥂✨🤗💕
Welcome to another Wegovy update ♥️ hope you all enjoy!
I’m on the road to 1k, so please hit that subscribe button if you haven’t done so already!! I appreciate all of you so much and thank you for being on this journey with me!
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**Disclaimer - This is my personal opinion, this is not medical advice, the information in this video is not a substitute for professional medical advice, diagnosis, or treatment - always consult with your doctor. **
Why Did Wegovy Weight Loss Become So Popular Obesity Fighters Club
Obesity is a widespread issue that affects millions of people worldwide. It is associated with numerous health complications, including diabetes, heart disease, and certain types of cancer. While diet and exercise are essential for weight management, some individuals may benefit from additional support in their weight loss journey. Recently, a new medication called Semaglutide Oral has shown promising results in helping individuals achieve weight loss goals. In this article, we will explore the benefits of Semaglutide Oral for weight loss and how it can help individuals struggling with obesity.
Increased Weight Loss
Semaglutide Oral is a medication that belongs to a class of drugs known as glucagon-like peptide-1 (GLP-1) receptor agonists. These drugs work by mimicking the effects of GLP-1, a hormone produced in the intestines that helps regulate blood sugar levels and appetite. Studies have shown that Semaglutide Oral can significantly increase weight loss compared to a placebo. In one study, participants who took Semaglutide Oral lost an average of 15% of their body weight, compared to just 2.4% in the placebo group.
One of the reasons why Semaglutide Oral is so effective for weight loss is its ability to reduce appetite and food cravings. By activating GLP-1 receptors in the brain, Semaglutide Oral helps individuals feel full sooner and consume fewer calories. This can lead to a reduced caloric intake, which is essential for weight loss. Additionally, Semaglutide Oral has been shown to improve insulin sensitivity and reduce inflammation, both of which play a role in metabolism and weight management.
Furthermore, Semaglutide Oral has been found to have a positive impact on other risk factors for obesity-related diseases, such as high blood pressure and cholesterol levels. By helping individuals achieve weight loss goals, Semaglutide Oral can also reduce the risk of developing serious health conditions like type 2 diabetes and cardiovascular disease. This makes it a valuable tool for individuals who are struggling to lose weight through diet and exercise alone.
Improved Quality of Life
In addition to promoting weight loss, Semaglutide Oral can also improve the overall quality of life for individuals with obesity. Excess weight can take a toll on physical health, leading to issues such as joint pain, fatigue, and difficulty performing daily tasks. By helping individuals achieve weight loss goals, Semaglutide Oral can alleviate these symptoms and improve mobility and energy levels.
Moreover, weight loss has been shown to have a positive impact on mental health and emotional well-being. Individuals who are overweight or obese may experience feelings of low self-esteem, depression, and anxiety due to societal stigma and personal struggles with body image. By providing a safe and effective option for weight loss, Semaglutide Oral can help individuals feel more confident and empowered in their bodies.
Overall, the benefits of Semaglutide Oral for weight loss extend beyond just physical health. By promoting weight loss and improving quality of life, Semaglutide Oral can empower individuals to take control of their health and well-being. With the support of this medication, individuals can achieve their weight loss goals and live happier, healthier lives.
Long-Term Weight Management
One of the challenges of weight loss is maintaining the results over the long term. Many individuals struggle to keep the weight off once they have reached their initial goals, leading to a cycle of yo-yo dieting and weight regain. However, Semaglutide Oral has shown promise in helping individuals sustain their weight loss over time.
Studies have found that individuals who take Semaglutide Oral are more likely to maintain their weight loss compared to those who do not. This is likely due to the appetite-suppressing effects of the medication, which can help individuals stick to healthier eating habits and avoid overeating. By providing ongoing support for weight management, Semaglutide Oral can help individuals prevent weight regain and maintain their progress for the long term.
Additionally, Semaglutide Oral has been shown to have a positive impact on metabolic health, which can further support long-term weight management. By improving insulin sensitivity and reducing inflammation, Semaglutide Oral can help individuals maintain a healthy metabolism and prevent weight-related complications like type 2 diabetes. This makes it an invaluable tool for individuals who are striving to achieve lasting weight loss success.
Safe and Effective Option
When considering weight loss medications, safety is a top priority for both individuals and healthcare providers. Semaglutide Oral has been extensively studied in clinical trials and has been shown to be a safe and effective option for weight loss. The medication is FDA-approved for the treatment of obesity, making it a trusted choice for individuals looking to achieve their weight loss goals.
In clinical trials, Semaglutide Oral has been found to have a favorable safety profile, with the most common side effects being nausea and diarrhea. These side effects are typically mild and tend to improve over time as the body adjusts to the medication. Additionally, Semaglutide Oral has not been associated with serious side effects like heart problems or addiction, which can be a concern with some weight loss medications.
Overall, Semaglutide Oral offers a safe and effective option for individuals struggling with obesity. By providing support for weight loss and long-term weight management, Semaglutide Oral can help individuals achieve lasting success in their journey towards a healthier lifestyle.
Cost-Effective Solution
For many individuals, the cost of weight loss medications can be a barrier to treatment. However, Semaglutide Oral offers a cost-effective solution for individuals looking to achieve weight loss goals. The medication is covered by most insurance plans, making it accessible to a wide range of individuals who may benefit from its effects.
Furthermore, the long-term benefits of Semaglutide Oral can lead to cost savings in the form of reduced healthcare expenses. By helping individuals achieve weight loss goals and improve metabolic health, Semaglutide Oral can lower the risk of developing obesity-related diseases like diabetes and heart disease. This can result in fewer doctor visits, medications, and hospitalizations, saving individuals money in the long run.
Overall, Semaglutide Oral is a cost-effective solution for individuals seeking support in their weight loss journey. By providing a safe and effective option that is accessible to most individuals, Semaglutide Oral can help individuals achieve their weight loss goals without breaking the bank.
Summary
In conclusion, Semaglutide Oral is a promising new option for individuals struggling with obesity. The medication offers a range of benefits, including increased weight loss, improved quality of life, and long-term weight management. With its safe and effective profile, Semaglutide Oral provides individuals with a valuable tool to support their weight loss goals. Additionally, the cost-effectiveness of the medication makes it an accessible option for individuals seeking support in their weight loss journey. Overall, Semaglutide Oral has the potential to help individuals achieve lasting success in their quest for a healthier lifestyle.
If you have any further questions about Semaglutide Oral for weight loss, please refer to the following FAQ section for more information.
FAQ:
Q: How does Semaglutide Oral work to promote weight loss?
A: Semaglutide Oral works by activating GLP-1 receptors in the brain, which help regulate appetite and reduce food cravings. This can lead to a reduced caloric intake and increased weight loss.
Q: What are the common side effects of Semaglutide Oral?
A: The most common side effects of Semaglutide Oral include nausea and diarrhea, which are typically mild and tend to improve over time.
Q: Is Semaglutide Oral a long-term solution for weight management?
A: Yes, Semaglutide Oral has been shown to help individuals maintain their weight loss over the long term by supporting healthy eating habits and metabolic health.
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NutraVesta Proven Review: Product Overview
With the weight loss market so difficult to navigate right now, it can be hard to know whether or not a product is right for you.
To make things easier, we’ve gathered up all you need to know about this new supplement:
Pros:
ProVen supplements are made of 100% natural ingredients
It means there are no harmful toxins that will be introduced into your body
ProVen focuses on a clean, healthy approach to weight loss.
ProVen does not include ingredients meant to induce a laxative effect.
Some weight loss supplements contain ingredients that work as laxatives to stimulate weight loss.
It can have serious and dangerous side effects and is an unhealthy and unsustainable way of losing weight.
ProVen’s supplements do not contain laxatives, making them a healthier alternative.
ProVen does not make outlandish claims about dramatic overnight weight loss.
Some weight loss companies claim that you can see dramatic weight loss in only a few weeks.
You should be very cautious with claims like these because often they claim you can lose dangerous amounts of weight in a short space of time.
Weight-loss like this is unsustainable! You should be focusing on the long term, sustainable changes over time, which will take months.
Cons
ProVen has not been tested by a third-party company.
While ProVen says on their site that they have conducted tests on obesity among clients, these are all in house tests.
They are only available to purchase online, which limits some of their customers.
ProVen is a very new product in the weight loss market. While some other brands have decided to focus solely on weight loss, delivering fast and unsustainable results, ProVen has moved away from that.
They have a new approach. ProVen have approached the creation of these supplements with a focus on holistic health. These supplements are packed full of antioxidants – ingredients that are thought to aid the body’s natural detoxification process and improve immune system functions.
The focus of this brand is not to make an overnight transformation purely for aesthetic purposes, like some other companies on the market right now.
Instead, ProVen focuses on overall health and weight loss as a part of that. Their ingredients don’t just have weight loss benefits, but also have benefits in other areas of general health, including decreased cholesterol and decreased risk of colds. This brand focuses on long term health rather than short term, sometimes unhealthy results.
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Pfizer is reversing course on developing a weight-loss pill after a patient in its trial suffered what's believed to be drug-induced liver injury.
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Exploring supplements and especially ensuring I'm supplementing electrolytes in the beginning stages of medical keto have been absolutely crucial in feeling well while making this transition. In this video, I share with you exactly which supplements I take and why, as well as what my keto coach Nicole Laurent has to say about some of the supplements she has recommended I take while on medical keto. I also share some of the supplements that I intend to explore in the future once I know how medical keto affects my illness, so that they are less confounding variables in this project.
Pill case I talk about being very useful: https://amzn.to/3vbjxq4
*UPDATE:*
Nicole had some additional insights regarding what I shared about taking ashwaganda and being interested in probiotics down the line. Here’s the advice she shared with me:
“I want to encourage you to not take that daily but on an as needed basis if you are dealing with a stressful time. On a ketogenic diet, your adrenal system starts working properly again. This herb is known to modulate hormones. I don't want it messing with your hormones because we are getting that back on track. It also has effects on liver, immune function and thyroid. It has neuromodulation effects on dopamine, serotonin and GABA! Your keto diet has got all those covered. It is a really powerful modulator in a body where things are not going well. But we do not understand it's effects in a body where things are going right. We don't know if the pathways modulated add to the ketogenic diet or get in the way. That said, I like a bit of Ashwagandha tea from time to time if I am feeling stressed for some reason, am a little tired, etc. I like Organic India brand.
And then probiotics! Please do not add a probiotic until we talk more about it first or even wait until after your six month experiment is over. The ketogenic diet radically changes the gut microbiome in favorable ways. We want to get out of it's way and let it do it's magic, which can include stopping seizures and helping put bipolar and schizophrenia in remission! As humans, and our current state of the research, we do not know best when it comes to microbiome. The ketogenic diet is already upregulating "good" bacteria in a sustainable way and rate that no probiotic is going to be able to touch. Also, most of the research on microbiome are not on ketogenic guts, although there are a few. So by all means go down the rabbit hole and explore in general, but I do not recommend you play with probiotics for yourself at this point in your recovery.”
Timestamps:
00:00 The mistake I made last time I tried keto
01:20 The pill case that makes it so much easier - find it here: https://amzn.to/3vbjxq4
02:34 Why I'm taking additional supplements more specifically for schizophrenia
03:20 Electrolytes (magnesium, potassium, sodium)
06:57 Acetyl L Carnitine
08:41 Vitamin D
09:10 Multivitamin
12:17 NAC and Glycine (precursors for glutathione)
15:04 Ashwaganda
15:33 I'm still on meds!!!
16:05 Supplements I intend to explore in the future (methylfolate, ginko biloba, sarcosine, omega 3 fatty acids, lion's mane, and probiotics
MEDICAL KETO RESOURCES
You can learn more about medical keto for mental illnesses on the Metabolic Mind YouTube channel (@metabolicmind) and on their website https://www.metabolicmind.org/
You can find more about my keto coach Nicole Laurent and her work on her website:
https://www.mentalhealthketo.com/
You can also learn more about metabolic health and mental illness from the book 'Brain Energy' by Dr. Christopher Palmer - https://brainenergy.com/
HOW TO TEST YOUR KETONES (important for medical keto!)
• The Keto Mojo blood glucose and ketone monitor is a finger prick blood test to accurately measure ketone and glucose levels. You can save 10% off monitor kits purchases and help support this content by using our affiliate link, thanks!: https://bit.ly/ketomojolivingwell
• The SiBio continuous ketone monitor is a wearable device we have been using to get accurate and continuous ketone levels. You can save 15% using the coupon code “LIVINGWELL15” and help support this content by using our affiliate link, thanks!: https://bit.ly/sibio
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Do weight loss meds really work?
✅ Yes—with the right one + lifestyle changes, you can lose 10–20% or more of your body weight.
From GLP-1s like Wegovy® and Zepbound® to options like metformin, we match you with what works for you.
*Learn more about each medication’s benefits and risks by visiting the manufacturer’s Prescribing Information webpage prior to starting any weight loss program.
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