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Fasting for prolonged periods can be a scary fast FAT LOSS tool, but what about if you’re concerned about MUSCLE LOSS? In this video the science will tell us if intermittent long term fasting can work for you also!
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In recent years the popularity of intermittent fasting for fat loss has led people to push the limits to longer term, extended fasts. This raises concerns about maintaining muscle mass, we all know that dietary protein is important to build muscle, but what about maintaining it? Over a 1 day or 2 day fast, what will happen to your muscles which were so painstaking to build.
Well thanks to the some incredible biological and hormonal processes involving Growth Hormone and IGF-1, the impact may not be as bad as you might think. In this video we dive in, to see exactly what is going on here. Uncovering some of the science behind what is happening, why its happening, and how we can use it to our best advantage, to build the best body!
First let’s be clear, all weight loss diets can be boiled down to one simple concept. You are reducing your calorie intake, thereby eating less calories than you burn, this forces your body to tap into fat to make up the difference. Converting this fat into energy reduces your fat mass while making up the additional energy you need.
In order to evaluate fasting as a way to lose fat for people interested in still preserving muscle, we need something to compare it against.
Since the goal here is fat loss with a consideration for maintaining muscle, it only makes sense to compare fasting against another similarly effective method of weight loss...
A typical cutting diet; which has participants eating less calories than they consume daily , meaning they schedule their macros so their deficit shows up at the end of each day.
The story of growth hormone release starts with the interactions of two other hormones. This is detailed in a fantastic study from 1992 published in the journal of clinical endocrinology and metabolism.
The first of these hormones is responsible for triggering the release of growth hormone, and is aptly named growth hormone releasing hormone.
the other is called Somatostatin or also sometimes called growth hormone-inhibiting hormone
Throughout the day and night, there are periodic releases of GHRH which should trigger the pituitary gland to release little blips of Growth Hormone. However sometimes this doesn’t work, while sometimes a secretion of GHRH triggers a burst of GH release, if GHIH is being secreted at the same time it cancels out the effects of the GHRH and GH isn’t released.
The result is small blips of growth hormone being released throughout the day into the bloodstream. What makes it even more difficult to study is is once released, growth hormone doesn’t stick around very long, the half life is quite short, in this study the average half life of GH in the blood was just 18 minutes.
During fasting mean levels of GH in the blood increased by 3 fold.
After a closer look they found the pituitary gland had kicked into overdrive, not only did the number of blips of GH release double, the average size of each blip increased as well.
as far as why it’s happening, science isn’t entirely sure, but the mechanism is hypothesized to be a result of an increase in that growth hormone release stimulating hormone, and a simultaneous decrease in the Somostatin which suppresses release as we talked about.
As far as benefits go,
It actually turns out, evidence for growth hormone itself impacting muscle growth and maintenance is mixed. The 1988 study I referenced suggested that GH may indirectly protect muscles by helping the body mobilize fat for fuel, and also support the liver in generating small amounts of necessary glucose.
While some studies have found GH increased muscle protein synthesis, others found no real effect on it…
So what is happening?
Well remember how I mentioned that GH doesn’t stick around very long once it enters the bloodstream, one reason for this is because when it reaches the liver it is transformed into ANOTHER hormone, known as IGF-1.
Unlike Growth Hormone, IGF-1 has a robust backing of scientific evidence supporting its important role in building and maintain muscle, to the point where injectable IGF-1 is a controlled substance under anti doping laws.
There are several well studied pathways which allow for muscle growth and maintenance, IGF-1 is deeply rooted in them.
Semaglutide is a drug that has gained notable attention in recent years for its potential to help individuals lose weight. Originally approved for the treatment of type 2 diabetes, Semaglutide has shown promising results in clinical trials for weight management in individuals with and without diabetes. Understanding how Semaglutide works and the benefits it can offer is essential for those considering this treatment option for weight loss.
Mechanism of Action
Semaglutide belongs to a class of medications known as glucagon-like peptide-1 (GLP-1) receptor agonists. This drug works by mimicking the effects of a naturally occurring hormone called GLP-1. GLP-1 is released in the gut in response to food intake and helps regulate blood sugar levels by increasing insulin secretion and decreasing glucagon secretion. In addition to its effects on blood sugar, GLP-1 also plays a role in appetite regulation and satiety, which can have implications for weight management.
When Semaglutide is injected, it activates GLP-1 receptors throughout the body, including the brain, pancreas, and gastrointestinal tract. By binding to these receptors, Semaglutide can help regulate blood sugar levels, reduce appetite, and increase the feeling of fullness after eating. These effects can lead to a decrease in food intake, improved glycemic control, and ultimately, weight loss.
Clinical Efficacy
Several clinical trials have demonstrated the efficacy of Semaglutide for weight loss in individuals with obesity or overweight. In one study, individuals receiving Semaglutide lost significantly more weight compared to those receiving a placebo. The weight loss achieved with Semaglutide was greater than that typically seen with other weight loss medications or lifestyle interventions alone.
Furthermore, Semaglutide has been shown to have additional benefits beyond weight loss. In some studies, Semaglutide was associated with improvements in cardiovascular risk factors, such as blood pressure and cholesterol levels. These findings suggest that Semaglutide may have a positive impact on overall health in addition to promoting weight loss.
Side Effects and Considerations
While Semaglutide has shown promise as a weight loss medication, it is not without potential side effects. Common side effects of Semaglutide include nausea, vomiting, diarrhea, and constipation, especially when starting treatment or increasing the dose. These side effects typically improve over time as the body adjusts to the medication.
It is important to note that Semaglutide is a prescription medication and should be used under the guidance of a healthcare provider. Individuals considering Semaglutide for weight loss should discuss the potential benefits and risks with their healthcare provider to determine if this treatment is appropriate for them. Additionally, Semaglutide should be used in conjunction with a healthy diet and exercise program for maximum effectiveness.
Conclusion
In conclusion, Semaglutide is a promising medication for weight loss that works by mimicking the effects of a hormone involved in appetite regulation and blood sugar control. Clinical trials have shown that Semaglutide can lead to significant weight loss and improvements in cardiovascular risk factors. However, it is important to consider the potential side effects and use Semaglutide under the guidance of a healthcare provider. With the right approach, Semaglutide may offer a valuable option for individuals looking to achieve their weight loss goals.
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It is the KetoACV diet that is the latest craze in town. Combining the natural power of the keto diet along with the detoxifying properties of apple cider vinegar, this progressive approach to weight loss and overall health has been making the rounds for what they say is its impressive results. But what is KetoACV and what can it do for your health? In this article, we investigate why the KetoACV diet has become so popular and if it works.
Understanding KetoACV
KetoACV, a dual-method diet, combines the ideas of the ketogenic diet and the addition of apple cider vinegar. The ketogenic diet, shortened to ‘keto’, is a high-fat, low-carbohydrate way of consuming food. It does so for the sole purpose of putting the body into ketosis. Once in this state, the body starts to use fats for energy and instead of glucose. In a similar manner to the more recent intermittent fasting trend, keto neatly skips around the nutritional practices of previous years. While the craze behind the keto diet has come and closely followed the hype around fasting, another product has persisted in remaining in the American food lovers circle. That’s apple cider vinegar – commonly ACV. ACV has been claimed to aid weight loss, prevent diabetes, aid with digestion, alleviate skin conditions, assist in an overall health regime, and even minimise inflammation.
A fundamental principle of the KetoACV diet is that people need to reduce their carb intake while increasing their fat intake. The underlying biochemical rationale here is that this shift in the ratio of macronutrient percentages compels the body to stop relying on carbohydrates for fuel and start burning fat instead. As long as people remain in this state known as ketosis, the theory goes, their bodies can effectively burn their own fat to fuel the body, hence the purported fat loss and other health benefits.
The KetoACV Diet’s formula of ½ to 1 tbsp of apple cider vinegar is touted as a supplement to the ketogenic diet that can enhance your health in ways that the ketogenic diet alone cannot. According to the suggested uses, apple cider vinegar can help with weight loss because drinking it can increase the feeling of satiety, decrease appetite and help you burn more calories while mastering your blood sugar levels. It has been suggested to assist in proper digestion and to reduce inflammation. This combination is thought to enhance your health and improve your weight-loss efforts.
The Benefits of KetoACV
There are a few possible benefits of the KetoACV diet, including weight loss. Carbohydrates are what people typically use as their main source of fuel. So, by removing that fuel source and replacing it with fat, the body can shift to fat metabolism, a process known as ketosis. Fat is burned for energy, which is the most rapid form of weight loss. Apple cider vinegar may also aid this process by making you feel more full.
Another possible benefit is better blood sugar control. Taking in fewer carbs and adding apple cider vinegar to your diet may help keep blood sugar more stable during the day, which can help you control cravings, feel more energetic, and prevent type 2 diabetes. The ketogenic diet itself improves how insulin works, too.
In addition to weight loss and blood sugar control, the KetoACV diet would theoretically offer other health benefits as well. Because the ketogenic diet suppresses inflammation and inflammation is involved in almost all chronic disease, reducing inflammation is an important factor in healing from disease. As noted above, apple cider vinegar has anti-inflammatory properties – a bonus for the KetoACV diet. If inflammation is responsible for much of the disease we see, reducing this inflammation might make you feel better.
Potential Drawbacks of KetoACV
Although the KetoACV diet has many potential advantages, it also may have some disadvantages to it. First, the ketogenic diet comprised in this programme can be quite restrictive; by severely limiting one’s carbohydrate intake, some people might find it difficult to consume enough calories and essential vitamins and minerals to meet their nutritional needs. Furthermore, as the ketogenic diet requires strict adherence to specific macronutrient ratios (ie, getting around 75 per cent of your calories from fat, around 20 per cent from protein, with almost zero carbs), it can be a challenge to stick with it long term.
Another possible pitfall of the KetoACV diet is side effects: starting the diet can make you feel tired, dizzy or lightheaded, cause a headache, and give you constipation. Those don’t happen to everyone who tries the KetoACV diet but they can affect people, and are sometimes referred to as the ‘keto flu’ as they usually go away once the body is transitioning to use fat for fuel. It’s possible that this ‘keto flu’ might be too unpleasant for some people, making it difficult to continue with the diet.
Last but not least, the KetoACV diet might not be suitable for everyone. For example, those with the disease diabetes, or those who have kidney disease, those battling or recovering from an eating disorder, or those who are pregnant or breastfeeding, should talk with a healthcare provider before starting such a diet plan. Overall, I’m of the opinion that you shouldn’t go on any one diet. Each person has to monitor their own health and wellbeing, and make decisions about what they want from a diet.
In summary, KetoACV diet is different weightloss and health strategy that incorporates the concept of the ketogenic diet with the health benefits of apple cider vinegar in order to assist individuals in losing weight quickly, maintaining healthy blood glucose levels, and other health benefits. There are however some potential downsides to KetoACV diet that must be considered such as micronutrient deficiencies, side effects and health status before altering their diet to KetoACV. It is therefore advisable to consult a medical practitioner or a nutritionist before beginning the diet.
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