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Emagreça comendo Existe uma dieta universal que seja boa pra todos que querem emagrecer ou manter a forma? A resposta é não! mas algumas regras básicas podem ser aplicadas, para quase todos. Dieta Paleolítica Dieta Cetogênica Dieta Mediterrânea Dieta de Atkins Dieta de South Beach Vegetariana, Vegana Jejum intermitente … a lista é antiga e enorme! Mas, seja qual for a dieta toda refeição deve ser consciente, onde cada mordisco represente uma escolha de sabores, texturas e aromas. Um ritual que nos conecta com a vida. A dieta não deve ser uma prisão e sim uma escolha saudável, um caminho para a harmonia, entre o corpo, a mente e a alma. Para falar sobre esse assunta está conosco a Dra Elaine Dias JK PHD em Endocrinologia pela Universidade de São Paulo, membro ativo da Sociedade Brasileira de Endocrinologia, com prática clínica que abrange desde o tratamento de distúrbios hormonais como Diabetes, Obesidade e doenças da Tireoide, até o desenvolvimento de programas avançados de emagrecimento e longevidade. Dra Elaine é também Palestrante em Congressos Nacionais e Internacionais e autora de publicações científicas relevantes em sua área de atuação. Claudete Troiano agradece: Gastronomia: Santa Bárbara Carnes Rua Dos Três Irmãos 524 Morumbi Telefone 11 2176 8400 @santabarbaracarnes Figurino: @anahi.shop Bijouxs: @ninobranacessorios Brindes:@wsadesivos Dra. Elaine Dias JK, PhD em endocrinologia pela USP e metabologista Site: www.elainedias.com.br Insta: @draelainedias e @draelainediasjk R. Oscar Freire, 2250 - Pinheiros, São Paulo - SP Telefone: (11) 98719-7733 Marcela Troiano: ‎@marcelatroiano   Instagram: @marcelatroiano_oficial Figurino: Instagram:@gregoryhenriqueschaumann Bijouxs: ‎@NinoBran  Instagram: @ninobranacessorios

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Follow along with Megan Miller, a Registered Dietitian, as she answers Frequently Asked Questions about Diet and GLP-1 while helping you build a nutritional foundation for a healthy lifestyle. (Part 7 of 10)

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Key Points Question Are glucagon-like peptide-1 receptor agonists semaglutide and liraglutide, which were originally introduced for the treatment of type 2 diabetes and are frequently prescribed due to their weight loss properties, associated with disproportionately increased reporting of suicidality? Findings This disproportionality analysis through the case-control design based on the World Health Organization global database collecting suspected adverse drug reactions, identified a disproportionality signal of suicidal ideation with semaglutide, which remained significant when comparing semaglutide with dapagliflozin and metformin and in the subgroup of patients with coreported use of antidepressants and benzodiazepines. Meaning A detected signal of semaglutide-associated suicidal ideation warrants urgent clarification. Abstract Importance Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have gained use primarily due to their weight-reduction effects, although a regulatory review was undertaken for potential suicidality concern. Objectives To evaluate potential signals for suicidal and self-injurious adverse drug reactions (ADRs) associated with the GLP-1 RAs semaglutide and liraglutide. Design, Setting, and Participants Disproportionality analysis through the case-control design using the World Health Organization (WHO) global database of suspected ADRs. Participants were clinical patients worldwide experiencing an ADR suspectedly attributable to semaglutide or liraglutide in the database from inception to August 30, 2023. Data were analyzed from September to December 2023. Exposure Treatment with semaglutide or liraglutide regardless of indication or treatment duration. Main Outcomes and Measures Reporting odds ratio (ROR) and the bayesian information component (IC) with 95% CIs were calculated as measures of disproportionate reporting of suicidal and self-injurious ADRs associated with semaglutide and liraglutide compared with all other medications. Sensitivity analyses were conducted including patients with coreported use of antidepressants and benzodiazepines and using dapagliflozin, metformin, and orlistat as comparators. A disproportionality signal was considered when the lower limits of the ROR and IC were above 1 and 0, respectively. Results A total of 107 (median [IQR] age 48 [40-56] years; 59 female patients [55%]) and 162 (median [IQR] age 47 [38-60] years; 100 female patients [61%]) cases of suicidal and/or self-injurious ADRs were reported between November 2000 and August 2023 with semaglutide and liraglutide, respectively. Significant disproportionality was detected only for semaglutide-associated suicidal ideation (ROR, 1.45; 95% CI, 1.18-1.77; IC, 0.53; 95% CI, 0.19-0.78), which remained significant in patients with coreported use of antidepressants (ROR, 4.45; 95% CI, 2.52-7.86; IC, 1.96; 95% CI, 0.98-2.63) and benzodiazepines (ROR, 4.07; 95% CI, 1.69-9.82; IC, 1.67; 95% CI, 0.11-2.65), when compared with dapagliflozin (ROR, 5.56; 95% CI, 3.23-9.60; IC, 0.70; 95% CI, 0.36-0.95), metformin (ROR, 3.86; 95% CI, 2.91-5.12; IC, 1.20; 95% CI, 0.94-1.53) and orlistat (ROR, 4.24; 95% CI, 2.69-6.69; IC, 0.70; 95% CI, 0.36-0.95). Conclusions and Relevance This study using the WHO database found a signal of semaglutide-associated suicidal ideation, which warrants urgent clarification.

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Das Ziel, Gewicht zu verlieren, ist für viele Menschen ein wichtiger Aspekt, um ihre Gesundheit zu verbessern und sich insgesamt wohler zu fühlen. Eine effektive Methode, um dieses Ziel zu erreichen, ist die Berechnung der Kalorienaufnahme. Indem man die Anzahl der Kalorien kontrolliert, die man täglich zu sich nimmt, kann man sicherstellen, dass man weniger Kalorien zu sich nimmt, als man verbrennt, was zu einem Gewichtsverlust führt. In diesem Artikel erfahren Sie, wie Sie Kalorien zum Abnehmen berechnen können und welche effektiven Methoden Ihnen dabei helfen können.

1. Bestimmung des Grundumsatzes

Der Grundumsatz ist die Menge an Kalorien, die Ihr Körper benötigt, um in Ruhe zu funktionieren, d.h. um die lebenswichtigen Funktionen wie Atmung, Herzschlag und Stoffwechsel aufrechtzuerhalten. Es gibt verschiedene Formeln, um Ihren Grundumsatz zu berechnen, basierend auf Faktoren wie Alter, Geschlecht, Gewicht und Größe. Eine einfache Methode ist die Harris-Benedict-Formel, die Ihnen einen groben Schätzwert für Ihren Grundumsatz liefert.

Um Ihren Grundumsatz mit der Harris-Benedict-Formel zu berechnen, multiplizieren Sie Ihr Körpergewicht in Kilogramm mit folgendem Wert:

– Für Frauen: 655 + (9,6 x Gewicht in kg) + (1,8 x Größe in cm) – (4,7 x Alter in Jahren)

– Für Männer: 66 + (13,7 x Gewicht in kg) + (5 x Größe in cm) – (6,8 x Alter in Jahren)

2. Bestimmung des Gesamtenergiebedarfs

Ihr Gesamtenergiebedarf setzt sich aus Ihrem Grundumsatz und dem sogenannten PAL (Physical Activity Level) zusammen, der angibt, wie aktiv Sie im Alltag sind. Um Ihren Gesamtenergiebedarf zu berechnen, multiplizieren Sie Ihren Grundumsatz mit dem PAL-Wert. Der PAL-Wert variiert je nach Aktivitätslevel, z.B.:

– Sehr leicht (sitzen, liegen): PAL-Wert von 1,2-1,4

– Leicht (sitzende Tätigkeit): PAL-Wert von 1,4-1,6

– Mittel (überwiegend stehende Tätigkeit): PAL-Wert von 1,6-1,8

– Schwer (körperliche Arbeit): PAL-Wert von 1,9-2,1

3. Bestimmung des Kaloriendefizits

Um abzunehmen, müssen Sie ein Kaloriendefizit von etwa 500 Kalorien pro Tag erreichen, was zu einem wöchentlichen Gewichtsverlust von etwa 0,5 kg führt. Durch die Kombination von Ernährungsumstellung und Bewegung können Sie dieses Kaloriendefizit erreichen. Beachten Sie jedoch, dass ein zu großes Kaloriendefizit zu gesundheitlichen Problemen führen kann, daher ist es wichtig, einen ausgewogenen Ansatz zu wählen.

Es ist ratsam, Ihre tägliche Kalorienzufuhr schrittweise zu reduzieren, anstatt drastische Veränderungen vorzunehmen, um Ihren Stoffwechsel nicht zu beeinträchtigen. Achten Sie darauf, ausreichend Proteine, gesunde Fette und komplexe Kohlenhydrate zu sich zu nehmen, um Ihren Körper mit allen wichtigen Nährstoffen zu versorgen.

4. Überwachung und Anpassung

Es ist wichtig, Ihre Kalorienzufuhr und Ihr Gewicht regelmäßig zu überwachen, um sicherzustellen, dass Sie auf dem richtigen Weg sind. Nutzen Sie dazu Apps oder Tagebücher, in denen Sie Ihre Mahlzeiten und Aktivitäten protokollieren können. Falls Sie nicht die gewünschten Ergebnisse sehen, passen Sie Ihre Kalorienzufuhr oder Ihr Aktivitätslevel entsprechend an, um Ihr Ziel zu erreichen.

Denken Sie daran, dass es wichtig ist, geduldig zu sein und realistische Ziele zu setzen. Ein gesunder Gewichtsverlust liegt bei etwa 0,5-1 kg pro Woche, also nehmen Sie sich Zeit und bleiben Sie konsequent. Konsultieren Sie bei Bedarf einen Ernährungsberater oder Arzt, um Unterstützung und professionelle Beratung zu erhalten.

5. Tipps und Tricks

Um Ihre Kalorienaufnahme zu reduzieren und den Gewichtsverlust zu unterstützen, gibt es einige Tipps und Tricks, die Ihnen helfen können. Zum Beispiel können Sie kleinere Portionen essen, langsam und bewusst essen, auf kalorienreiche Getränke verzichten, gesunde Snacks vorbereiten und regelmäßig Sport treiben. Diese kleinen Veränderungen können einen großen Unterschied machen und Ihnen helfen, Ihre Ziele schneller zu erreichen.

Denken Sie daran, dass Abnehmen ein Prozess ist, der Geduld, Engagement und Disziplin erfordert. Seien Sie stolz auf jede erreichte Meilenstein und feiern Sie Ihre Erfolge, auch wenn sie klein sind. Durch eine bewusste Ernährung, regelmäßige Bewegung und eine positive Einstellung können Sie Ihr Ziel erreichen und ein gesünderes Leben führen.

—

Zusammenfassung und FAQ

In diesem Artikel haben Sie gelernt, wie Sie Kalorien zum Abnehmen berechnen können, angefangen mit der Bestimmung Ihres Grundumsatzes und Gesamtenergiebedarfs bis hin zur Überwachung und Anpassung Ihrer Kalorienzufuhr. Indem Sie ein Kaloriendefizit von etwa 500 Kalorien pro Tag erreichen und Ihre Ernährung und Bewegung anpassen, können Sie Ihren Gewichtsverlust unterstützen und Ihre Ziele schneller erreichen.

Wenn Sie weitere Fragen haben oder Unterstützung benötigen, zögern Sie nicht, einen Ernährungsberater oder Arzt zu konsultieren, um individuelle Unterstützung und Beratung zu erhalten. Bleiben Sie motiviert, setzen Sie realistische Ziele und vertrauen Sie auf sich selbst, um Ihren Weg zu einem gesünderen Lebensstil zu gehen. Viel Erfolg auf Ihrer Reise zum Abnehmen und zur Verbesserung Ihrer Gesundheit!

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