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Learn about the design of a trail-blazing Randomized Controlled Trial (RCT) that will explore the physiology and biology of brain energy metabolism, while also informing clinical applications of ketogenic therapy as an adjunctive treatment option for patients with bipolar and schizophrenia spectrum disorders. RCTs are considered the gold standard when looking at the efficacy and safety of new treatment options. This type of research is necessary to understand whether ketogenic therapy should be offered as a first-line treatment option, as well as what types of strategies could increase accessibility of this intervention in the future. Dr. Bret Scher interviews principal investigators Dost Öngür, MD, PhD, and Dr. Virginie-Anne Chouinard, MD, about the details of this trial at McLean Hospital, a top-rated, Harvard-affiliated psychiatric hospital.
Learn more about the impressive design of this trial which includes a multidisciplinary approach to clinical care, gathering a variety of data to inform understanding of underlying brain energy mechanisms (including MRIs and metabolic markers), and an “open-label” approach that will allow the control group to opt into ketogenic therapy at the end of the first trial phase if desired.
Dr. Dost Öngür
William P. and Henry B. Test Professor of Psychiatry, Chief of the Division of Psychotic Disorders, & Director of the Schizophrenia and Bipolar Disorder Research Program at McLean Hospital
https://www.mcleanhospital.org/profile/dost-ongur
Dr. Virginie-Anne Chouinard,
Staff psychiatrist and Director of Research at McLean OnTrack™ & Instructor in Psychiatry at Harvard Medical School.
https://www.mcleanhospital.org/profile/virginie-anne-chouinard
Press release about the trial:
https://www.prnewswire.com/news-releases/mclean-hospital-launches-clinical-trial-of-ketogenic-therapy-for-bipolar-disorder-302062402.html
For information on enrolling:
https://clinicaltrials.gov/study/NCT06221852
Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.
Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/
About us:
Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.
Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.
Timestamps
0:00 Introduction
2:03 Interest leading up to a keto for bipolar study
5:36 Brain energy metabolism and bipolar
7:44 Patient population for the new Harvard study
8:46 About the study
9:21 Dietary studies vs pharmacologic studies
11:55 The different interventions in the keto for bipolar study
14:42 What researchers will be looking at during the clinical trial
17:20 Balancing mechanism and clinical impact in research
19:21 Impact of the clinical trial
21:54 Working with a clinician for ketogenic therapy
25:30 Conclusion
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03:11 Tip 1: Goals
05:34 Tip 2: Alcohol
09:04 Tip 3: Hydrate
11:47 Tip 4: Buffets
16:51 Tip 5. Main Dining Room
19:27 Tip 6. Specialty Dining
22:19 Tip 7. Staying Active on the Ship
25:30 Tip 8. Excursions
27:49 Tip 9. Snacking and Final Tips
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In today's video, I will give a complete review of PURAVIVE.
PURAVIVE is a food supplement that promises to help with healthy weight loss with 100% natural ingredients. Puravive promises to activate sleep metabolism, in other words, lose weight while sleeping! Will it really work? Watch this video until the end and check out all the details!
We have prepared a complete review video with all the important warnings, which I will talk about throughout the video, so pay close attention to avoid making mistakes when using or purchasing Puravive.
Learn the correct way to buy and use Puravive and what the side effects of Puravive are!
Attention, be careful when purchasing Puravive on any website, you run the risk of not getting the benefits of the guarantee or even being scammed, so prepare a direct link to the official JAVABURN website below.👇
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When it comes to the world of keto supplements, Let’s Keto Gummies have been making waves. These gummies are marketed as a convenient way to get your daily dose of ketones without the hassle of traditional supplements. But with a price tag that might make some people hesitant to try them, many are left wondering – are Let’s Keto Gummies really worth the cost?
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Let’s Keto Gummies are made with a blend of powerful ingredients like BHB ketones, MCT oil, and collagen. These ingredients are believed to help promote ketosis, boost energy levels, and support weight loss. Additionally, the gummies are said to taste great and are easy to incorporate into your daily routine.
Many users report feeling more alert and focused after taking Let’s Keto Gummies, which can be especially helpful for those following a ketogenic diet. The combination of ingredients in these gummies can provide a quick energy boost without the crash that comes from traditional energy drinks or supplements.
Overall, the ingredients in Let’s Keto Gummies seem to offer a range of benefits that can support a keto lifestyle. While the price may be higher than other supplements on the market, the quality of the ingredients and the convenience of the gummies may make them worth it for some users.
User Experience
Users of Let’s Keto Gummies have had mixed reviews about their experience with the product. Some have reported significant weight loss and increased energy levels, while others have not seen any noticeable changes after taking the gummies.
One common complaint among users is the price of Let’s Keto Gummies. Some feel that the cost is too high for a supplement, especially when compared to other options on the market. Additionally, some users have experienced digestive issues after taking the gummies, which can be a concern for those with sensitive stomachs.
Despite the mixed reviews, many users continue to use Let’s Keto Gummies for the convenience and potential benefits they offer. For those who are looking for a quick and easy way to support their keto lifestyle, these gummies may be worth the investment.
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Let’s Keto Gummies are available for purchase online through the company’s website as well as select retailers. The price of these gummies can vary depending on the quantity you purchase, with larger quantities often offering a better value per gummy.
While the price of Let’s Keto Gummies may be higher than other supplements, many users find the convenience and quality of the product worth it. The company often runs promotions and discounts, so it’s worth keeping an eye out for deals if you’re interested in trying these gummies.
Overall, the availability and pricing of Let’s Keto Gummies make them accessible to a wide range of users who are looking for a convenient way to support their keto lifestyle. With the potential benefits they offer, these gummies may be worth the investment for some.
So, are Let’s Keto Gummies worth the price? The answer ultimately depends on your individual needs and preferences. If you’re looking for a convenient way to support your keto lifestyle and are willing to invest in quality ingredients, these gummies may be worth it for you.
While the price may be a concern for some, the benefits and user experience of Let’s Keto Gummies can outweigh the cost for many users. It’s important to weigh the pros and cons and make an informed decision based on your own research and goals.
In conclusion, Let’s Keto Gummies offer a unique and convenient way to support your keto journey. With a blend of powerful ingredients and potential benefits, these gummies may be worth the investment for those looking for a quick and easy way to stay in ketosis and boost energy levels.
